Find 5 Star Hotels in Panama City, FL from AED 176

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Check availability on Panama City 5 Star Hotels

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Compare Panama City 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Indigo Panama City Marina by IHG

3.5 star property
9.6 out of 10, Exceptional, (213)
"We loved it there and can’t wait to go back "
The price is AED 606
AED 686 total
includes taxes & fees
2 Mar - 3 Mar
Hotel Indigo Panama City Marina by IHG

Best Western Plus Panama City Hotel

2.5 star property
8.4 out of 10, Very Good, (676)
"Close to main shopping and dining areas. The heaters and air-conditioning was broke but they had a portable unit that worked. Took a few minutes to figure it out though."
The price is AED 304
AED 344 total
includes taxes & fees
4 Mar - 5 Mar
Best Western Plus Panama City Hotel

La Quinta Inn & Suites by Wyndham Panama City

3.0 star property
8.6 out of 10, Excellent, (1002)
"Everything "
The price is AED 248
AED 346 total
includes taxes & fees
30 Mar - 31 Mar
La Quinta Inn & Suites by Wyndham Panama City

Hilton Garden Inn Panama City Airport

3.0 star property
9.4 out of 10, Exceptional, (500)
"Convenient and had what I needed! "
The price is AED 419
AED 448 total
includes taxes & fees
9 Mar - 10 Mar
Hilton Garden Inn Panama City Airport

Ramada by Wyndham Panama City

2.0 star property
6.4 out of 10, (1002)
"Decent stay . Nothing horrible , Nothing remarkable either. "
The price is AED 187
AED 212 total
includes taxes & fees
5 Mar - 6 Mar
Ramada by Wyndham Panama City

Holiday Inn Panama City by IHG

3.0 star property
8.6 out of 10, Excellent, (671)
"Everything was great. Hotel was clean and very comfortable! "
The price is AED 496
AED 561 total
includes taxes & fees
3 Mar - 4 Mar
Holiday Inn Panama City by IHG

Hilton Garden Inn Panama City

3.0 star property
8.6 out of 10, Excellent, (465)
"The hotel was clean, quiet, easy to check in and out, close to shopping and restaurants, nice beds and showers. Breakfast onsite. Friendly staff. "
The price is AED 434
AED 491 total
includes taxes & fees
7 Mar - 8 Mar
Hilton Garden Inn Panama City

Comfort Inn & Suites Panama City North

2.5 star property
8.0 out of 10, Very Good, (494)
"Clean and comfortable and affordable "
The price is AED 291
AED 330 total
includes taxes & fees
9 Mar - 10 Mar
Comfort Inn & Suites Panama City North

Courtyard by Marriott Panama City

3.0 star property
9.0 out of 10, Wonderful, (324)
"Very nice hotel with excellent staff. Clean and comfortable. "
The price is AED 419
AED 474 total
includes taxes & fees
30 Mar - 31 Mar
Courtyard by Marriott Panama City

Country Inn & Suites by Radisson, Panama City, FL

2.5 star property
7.4 out of 10, Good, (743)
"Great stay great location great staff "
The price is AED 281
AED 318 total
includes taxes & fees
2 Mar - 3 Mar
Country Inn & Suites by Radisson, Panama City, FL

Quality Inn & Conference Center

2.5 star property
7.6 out of 10, Good, (514)
"Nothing to complain about so dar!"
The price is AED 272
AED 307 total
includes taxes & fees
3 Mar - 4 Mar
Quality Inn & Conference Center

Microtel Inn & Suites by Wyndham Panama City

2.0 star property
6.6 out of 10, (877)
"Loved the place "
The price is AED 275
AED 311 total
includes taxes & fees
3 Mar - 4 Mar
Microtel Inn & Suites by Wyndham Panama City

Days Inn by Wyndham Panama City

2.5 star property
5.2 out of 10, (682)
"👍"
The price is AED 203
AED 230 total
includes taxes & fees
2 Mar - 3 Mar
Days Inn by Wyndham Panama City

TownePlace Suites by Marriott Panama City

3.0 star property
8.4 out of 10, Very Good, (159)
"Room was clean and kitchenette worked well. "
The price is AED 417
AED 467 total
includes taxes & fees
4 Mar - 5 Mar
TownePlace Suites by Marriott Panama City

Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG

2.5 star property
8.4 out of 10, Very Good, (398)
"The cleanliness of the establishment, the layout of the rooms and the overall friendly of all staff members."
The price is AED 485
AED 519 total
includes taxes & fees
22 Mar - 23 Mar
Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG

Days Inn by Wyndham Panama City/Callaway

2.0 star property
6.8 out of 10, (371)
"Front desk staff is always amazing "
The price is AED 253
AED 271 total
includes taxes & fees
2 Mar - 3 Mar
Days Inn by Wyndham Panama City/Callaway

Red Roof Inn Panama City

2.0 star property
8.2 out of 10, Very Good, (1002)
"We just dropped off the grandkids and just wanted a place to rest overnight before we continued our journey. Red roof Inn has remodeled the rooms looks great love that they have engineer flooring instead of carpet. It not only looks great, but it just feels cleaner and there’s no carpet smell And makes the room look bigger. The red roof Inn has really improved from past red roof ends that I’ve stayed at."
The price is AED 309
AED 349 total
includes taxes & fees
2 Mar - 3 Mar
Red Roof Inn Panama City

Suburban Studios near Panama City Beach

2.0 star property
7.4 out of 10, Good, (300)
"Everything was good, like the small kitchen in the room. Only issue was that you can smell other people’s food in the hallway, since almost everyone was cooking. Over all it’s a good hotel for the price "
The price is AED 215
AED 243 total
includes taxes & fees
13 Mar - 14 Mar
Suburban Studios near Panama City Beach

Comfort Suites

2.5 star property
8.6 out of 10, Excellent, (632)
"Employee at the front desk very friendly and helpful. Room spacious and clean. Breakfast was very good. Breakfast lady very friendly and helpful too. Loved the omelets ans sausage links."
The price is AED 380
AED 407 total
includes taxes & fees
17 Mar - 18 Mar
Comfort Suites

Comfort Inn & Suites

2.5 star property
8.2 out of 10, Very Good, (867)
"checked in really late and they held our reservation, the room was clean, bathroom was big, very quiet, and the pool was clean and very nice"
The price is AED 309
AED 350 total
includes taxes & fees
13 Mar - 14 Mar
Comfort Inn & Suites
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Frequently asked questions

How much does it cost to stay in a 5-star hotel in Panama City?
You can find several pricing options for a 5-star hotel in Panama City on Expedia. How much you’ll pay will depend on when you want to travel, length of your trip and other factors. Compare available properties for your chosen dates and use our pricing and other filters to discover the ideal luxury stay.

  • Search for the lowest price per night from AED 309

What makes a hotel 5 stars in Panama City?
In Panama City, a hotel must offer a certain number of high-end amenities to be rated 5 stars. These can include on-site gyms, saunas and spas, gourmet restaurants, luxury bathroom products, premium bedding and more. What also sets 5-star hotels apart is their exceptional standard of service. You can look forward to things like concierge services, in-room massages and nightly turn-down services. Some may even offer additional touches such as a welcome gift.
Are there any 5-star all-inclusive resorts in Panama City?
Find a luxurious escape that includes your room, meals, drinks and entertainment in Panama City with our filter tool. Search for resorts with a 5-star rating and select the “All inclusive” filter. Make sure you check what’s included in the price. That way, you can take full advantage of all the perks on offer from the moment you get there.
Are there any 5-star vacation rentals in Panama City?
There are no 5-star vacation rentals in Panama City on our site, but there are a range of other highly rated options worth checking out. Scan through our vacation rentals in Panama City to book the best place for your stay.