Find 4 Star Hotels in Serra Mesa, CA from AED 459

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Compare Serra Mesa 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

San Diego Marriott Gaslamp Quarter

4.0 star property
8.6 out of 10, Excellent, (1324)
"Did not like the $65 daily parking rate and no refrigerator or microwave "
The price is AED 621
AED 700 total
includes taxes & fees
23 Feb - 24 Feb
San Diego Marriott Gaslamp Quarter

Hyatt Regency Mission Bay Spa and Marina

4.0 star property
8.4 out of 10, Very Good, (1451)
"Great experience. Pool and waterslides were perfect for my 6 and 3 year old boys. Hotel room was beautiful. We will come again. Breakfast was mediocre. Service was ok. Waiter was passive aggressive. Could have done without. "
The price is AED 621
AED 861 total
includes taxes & fees
23 Feb - 24 Feb
Hyatt Regency Mission Bay Spa and Marina

Sheraton San Diego Resort

4.0 star property
8.0 out of 10, Very Good, (2564)
"Love the hotel and the views are spectacular"
The price is AED 621
AED 849 total
includes taxes & fees
7 Mar - 8 Mar
Sheraton San Diego Resort

Omni San Diego Hotel

4.0 star property
9.0 out of 10, Wonderful, (1843)
"Nice location and hotel"
The price is AED 644
AED 887 total
includes taxes & fees
16 Mar - 17 Mar
Omni San Diego Hotel

Manchester Grand Hyatt San Diego

4.0 star property
9.0 out of 10, Wonderful, (2809)
"Nice location and hotel!"
The price is AED 694
AED 957 total
includes taxes & fees
6 Mar - 7 Mar
Manchester Grand Hyatt San Diego

San Diego Marriott La Jolla

4.0 star property
8.4 out of 10, Very Good, (1606)
"Closer to shopping center, restaurant and movie theater."
The price is AED 526
AED 594 total
includes taxes & fees
1 Mar - 2 Mar
San Diego Marriott La Jolla

Hotel Indigo San Diego-Gaslamp Quarter by IHG

4.0 star property
8.6 out of 10, Excellent, (1003)
"Excellent hotel and location. Staff was friendly, rooms were clean and comfortable, and the food was excellent. Will stay here every time we visit San Diego "
The price is AED 694
AED 915 total
includes taxes & fees
23 Feb - 24 Feb
Hotel Indigo San Diego-Gaslamp Quarter by IHG

Loews Coronado Bay Resort

4.0 star property
8.8 out of 10, Excellent, (1004)
"Staff was very nice. I just wish we would have known about the shuttle at checkin. We didn't rent a car so we didn't want to uber back and forth. If we knew about the shuttle earlier we would have gone into town more. "
The price is AED 768
AED 1,020 total
includes taxes & fees
23 Feb - 24 Feb
Loews Coronado Bay Resort

Wyndham San Diego Bayside

4.0 star property
8.2 out of 10, Very Good, (5617)
"Only downside for me was cost to park a car ($50/day)"
The price is AED 590
AED 665 total
includes taxes & fees
16 Mar - 17 Mar
Wyndham San Diego Bayside

Marriott Marquis San Diego Marina

4.0 star property
9.0 out of 10, Wonderful, (1615)
"It was a great experience at the Marriot Marquis San Diego Marina. The staff and services were great, the hotel is beautiful, clean, and conveniently located by surrounding restaurants and shops. Everything is pretty much a walking distance, which is a good thing because parking was tough. We paid ahead for parking and still had to circle the hotel lot for 30 plus minute until we found a spot. Once in the spot we decided not to move the car until checkout, in fear that we would not find a spot...
The price is AED 764
AED 991 total
includes taxes & fees
7 Mar - 8 Mar
Marriott Marquis San Diego Marina

Alma San Diego Downtown, a Tribute Portfolio Hotel

4.0 star property
8.8 out of 10, Excellent, (479)
"We had a great experience at the Alma. The room was comfortable, service was great. We had all the amenities we needed."
The price is AED 508
AED 701 total
includes taxes & fees
16 Mar - 17 Mar
Alma San Diego Downtown, a Tribute Portfolio Hotel

Hilton San Diego Bayfront

4.0 star property
8.4 out of 10, Very Good, (1524)
"Great location. Under staffed "
The price is AED 655
AED 912 total
includes taxes & fees
14 Mar - 15 Mar
Hilton San Diego Bayfront

Lafayette Hotel & Club

4.0 star property
9.0 out of 10, Wonderful, (619)
"This is the most beautiful and amazing hotel!"
The price is AED 757
AED 851 total
includes taxes & fees
23 Feb - 24 Feb
Lafayette Hotel & Club

Hilton San Diego Mission Valley

4.0 star property
8.0 out of 10, Very Good, (1492)
"close to highway, a little bit noisy"
The price is AED 459
AED 518 total
includes taxes & fees
2 Mar - 3 Mar
Hilton San Diego Mission Valley

The Guild Hotel, San Diego, A Tribute Portfolio Hotel by Marriott

4.0 star property
9.0 out of 10, Wonderful, (751)
"very nice, only place i stay at in san diego"
The price is AED 492
AED 700 total
includes taxes & fees
16 Mar - 17 Mar
The Guild Hotel, San Diego, A Tribute Portfolio Hotel by Marriott

Paradise Point Resort & Spa

4.0 star property
8.6 out of 10, Excellent, (2090)
"An amazing staycation, it felt like we were in an island in Hawaii "
The price is AED 739
AED 1,015 total
includes taxes & fees
23 Feb - 24 Feb
Paradise Point Resort & Spa

Hard Rock Hotel San Diego

4.0 star property
8.8 out of 10, Excellent, (2577)
"It was a great stay staff super professional "
The price is AED 585
AED 825 total
includes taxes & fees
23 Feb - 24 Feb
Hard Rock Hotel San Diego

Embassy Suites by Hilton San Diego Bay Downtown

4.0 star property
8.8 out of 10, Excellent, (1141)
"Property was very nice. The food for breakfast needs a little help. The happy hour was ok. Other than that amazing stay."
The price is AED 809
AED 1,015 total
includes taxes & fees
14 Mar - 15 Mar
Embassy Suites by Hilton San Diego Bay Downtown

Embassy Suites by Hilton San Diego La Jolla

4.0 star property
8.8 out of 10, Excellent, (1389)
"Parking was small, rest was great. "
The price is AED 584
AED 658 total
includes taxes & fees
7 Mar - 8 Mar
Embassy Suites by Hilton San Diego La Jolla

Legacy Resort Hotel & Spa

4.0 star property
9.2 out of 10, Wonderful, (2890)
"I stay here on all my trips to San Diego. It never disappoints. Staff is always very helpful and friendly. The food at the on-site restaurant is excellent, the service is very good."
The price is AED 585
AED 659 total
includes taxes & fees
23 Feb - 24 Feb
Legacy Resort Hotel & Spa
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Explore similar 5-star hotels

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the best 4-star hotels in Serra Mesa?
San Diego Marriott Mission Valley and DoubleTree by Hilton Hotel San Diego - Mission Valley are two top-rated escapes located in or near Serra Mesa. Both have a 4-star rating and offer high-end comfort alongside an unbeatable traveler experience. Book a stay at the first and make use of concierge services and premium bedding. The second has designer toiletries and a swimming pool, among many amenities.
How much does it cost to stay in a 4-star hotel in Serra Mesa?
Expedia can help you quickly locate the ideal 4-star hotel for your stay in Serra Mesa. Use our filter tool to tailor your search by things like price, amenities and hotel star rating and get access to awesome deals in a few clicks.

  • Search for the lowest price from AED 933

What's the difference between 5-star and 4-star hotels in Serra Mesa?
Offering a friendly guest experience and upmarket décor, 4-star hotels are a wonderful option for your Serra Mesa vacation. These kinds of stays generally feature lots of useful amenities that make it a breeze to unpack and relax — think 24-hour room service, restaurants and pools. Or enjoy even more lavishness at a 5-star hotel designed to pamper with exclusive perks and amenities. Concierge assistance, premium toiletries and gourmet dining are typically featured at these deluxe properties.
Does Serra Mesa have any 4-star all-inclusive resorts?
Our “All inclusive” filter makes it easy to search for your dream resort. You’ll also find other standard 4-star stays like DoubleTree by Hilton Hotel San Diego - Mission Valley and San Diego Marriott Mission Valley. Offering the same level of luxury and comfort, they are excellent options for your Serra Mesa getaway.
What are the top 4-star apartments in Serra Mesa?
Expedia guests love stays like Lyric | San Diego Boutique Suites because they typically offer more space and privacy than a standard hotel. Select this or another of our 4-star properties in Serra Mesa and experience that home-away-from-home ambience during your escape.