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Compare 26,713 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Algila' Ortigia Charme Hotel

4.0 star property
9.6 out of 10, Exceptional, (810)
"We enjoyed our stay"
The price is AED 1,621
AED 1,824 total
includes taxes & fees
23 May - 24 May
Algila' Ortigia Charme Hotel

Hotel Livingston Siracusa

4.0 star property
9.0 out of 10, Wonderful, (244)
"Wonderful location! Walking distance to all of Ortigia. Highly recommended."
The price is AED 977
AED 1,116 total
includes taxes & fees
21 May - 22 May
Hotel Livingston Siracusa

Domus Mariae Benessere

3.0 star property
9.0 out of 10, Wonderful, (217)
"My husband & I stayed 2 nights in mid-May 2025. We loved this historic and fascinating B&B within a current convent (yes, we saw the nuns!). Comfortable 2nd floor room that opened onto a quiet, shared, shaded terrace. There’s also a ln upper terrace with seattle & sea views. The staff were very friendly and helpful. Note: wifi was very unreliable. We parked our rental car at the Talete garage about 10 minutes walk, for €15 per 24 hrs. Overall, this was a great location for us in Ortigia."
The price is AED 716
AED 870 total
includes taxes & fees
25 May - 26 May
Domus Mariae Benessere

Caportigia Boutique Hotel

5.0 star property
9.4 out of 10, Exceptional, (229)
"The staff were lovely, the breakfast was good. Great location to walk Ortigia."
The price is AED 628
AED 731 total
includes taxes & fees
8 Jun - 9 Jun
Caportigia Boutique Hotel

Mercure Siracusa Prometeo

4.0 star property
9.0 out of 10, Wonderful, (449)
"Excellent breakfast and great evening meals too. The receptionists were absolutely super in giving us advice on local transport and visitor attractions. The waiters and waitresses were also very friendly and helpful and very accommodating in explanations and assistance. Highly recommended."
The price is AED 388
AED 468 total
includes taxes & fees
9 Jun - 10 Jun
Mercure Siracusa Prometeo

Domus Mariae Albergo

3.0 star property
9.2 out of 10, Wonderful, (289)
"Great location with friendly staff. "
The price is AED 633
AED 738 total
includes taxes & fees
22 May - 23 May
Domus Mariae Albergo

Hotel Gargallo

3.0 star property
8.6 out of 10, Excellent, (124)
"The hotel is perfectly located in Ortigia, quiet at night and breakfast was nice"
The price is AED 583
AED 665 total
includes taxes & fees
26 May - 27 May
Hotel Gargallo

Nostos rooms & Apartments

3.0 star property
9.0 out of 10, Wonderful, (255)
"Very welcoming staff "
The price is AED 276
AED 314 total
includes taxes & fees
3 Jun - 4 Jun
Nostos rooms & Apartments

Dimore delle Zagare Ortigia

9.8 out of 10, Exceptional, (140)
"Wonderful place, clean and stuff superb. One of the best places we stayed. "
The price is AED 797
AED 917 total
includes taxes & fees
9 Jun - 10 Jun
Dimore delle Zagare Ortigia

PhotoGuest

3.0 star property
9.8 out of 10, Exceptional, (157)
"Nice inside. Outside not so much."
The price is AED 538
AED 613 total
includes taxes & fees
22 May - 23 May
PhotoGuest

Charme Hotel Henry's House

4.0 star property
9.6 out of 10, Exceptional, (287)
"Breakfast was very nice. "
The price is AED 1,145
AED 1,301 total
includes taxes & fees
19 Jun - 20 Jun
Charme Hotel Henry's House

Maniace Boutique Hotel Ortigia UNA Esperienze

9.8 out of 10, Exceptional, (15)
"Lovely hotel, excellent service, perfect location."
The price is AED 1,164
AED 1,321 total
includes taxes & fees
15 Jun - 16 Jun
Maniace Boutique Hotel Ortigia UNA Esperienze

Palazzo Gilistro

9.8 out of 10, Exceptional, (130)
"Lovely hotel in the centre. The staff were wonderful. Breakfast superb. Great view from the balcony. Would recommend."
The price is AED 694
AED 805 total
includes taxes & fees
8 Jun - 9 Jun
Palazzo Gilistro

Lanterne Magiche Ortigia

9.4 out of 10, Exceptional, (127)
"Austerely elegant, clean, great breakfast and super wonderful staff."
The price is AED 634
AED 738 total
includes taxes & fees
27 May - 28 May
Lanterne Magiche Ortigia

Hotel Posta

3.0 star property
8.4 out of 10, Very Good, (420)
"Wonderfully charming hotel in a great location with ample paid parking nearby. Our beds were comfortable and the bathroom was clean and modern. The included continental breakfast was very good and satisfying. Anna and her team made our stay very enjoyable and accomodated our extra requests, which just made our stay in wonderful Syracuse that much better. Very professionally run hotel that I would definitely visit again."
The price is AED 404
AED 460 total
includes taxes & fees
26 May - 27 May
Hotel Posta

Giuggiulena Villa

3.0 star property
10.0 out of 10, Exceptional, (120)
"Sabrina and Claudia are consummate hosts and understand what constitutes a high-end experience! The accommodation was spotlessly clean, the shower powerful and the rooms spacious with every comfort needed. Staying at the Giuggiulena Villa was the perfect start to our holiday, we were made to feel at home immediately! Claudia and Sabrina prepared dinner for us for the three evenings we stayed and the food was superb! We highly recommend this B & B and won’t hesitate to stay with them again when...
The price is AED 1,229
AED 1,393 total
includes taxes & fees
11 Jun - 12 Jun
Giuggiulena Villa

B&B Nike

9.0 out of 10, Wonderful, (64)
"Clean, good location. "
The price is AED 330
AED 376 total
includes taxes & fees
25 May - 26 May
B&B Nike

Palazzo Artemide - VRetreats

4.0 star property
9.4 out of 10, Exceptional, (626)
"Excellent location and friendly staff!"
The price is AED 1,182
AED 1,341 total
includes taxes & fees
19 Jun - 20 Jun
Palazzo Artemide - VRetreats

Calafatari B&B

3.0 star property
10.0 out of 10, Exceptional, (4)
"Wonderful property, well located, and memorable caring service. Anna was an outstanding host, cares and serves us every day with local fresh pastries, fruits, salumeria, assorted juices and marmalades. Grazing table all day. Room was wonderful. Lots of free and safe parking in the area. I highly recommend it."
Calafatari B&B

Fortaleza Charme House

9.8 out of 10, Exceptional, (10)
"Very helpful host who shared lots of recommendations and tips. Great location and very nice rooms."
The price is AED 540
AED 636 total
includes taxes & fees
16 Jun - 17 Jun
Fortaleza Charme House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Syracuse

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Where to stay in Syracuse

Find the best Syracuse areas and neighborhoods for the activities you enjoy most.
Ortigia map

Ortigia

4 out of top 10 points of interest in this area

The historic heart of Syracuse is dotted with churches and atmospheric piazzas, where visitors enjoy sweeping sea views while dining at gourmet restaurants.

Santa Lucia map

Santa Lucia

1 out of top 10 points of interest in this area

Santa Lucia is noteworthy for its historic sites, and you can make a stop at top attractions like Porto Piccolo and Ionian Sea.

Tiche map

Tiche

Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.

Acradina map

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

Grottasanta map

Grottasanta

Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

Learn more about Syracuse

Trip time! Discover the history, culture, and seaside in Syracuse.

Syracuse showing street scenes as well as an individual femail

Frequently asked questions

What's the best place to stay in Syracuse?

B&B Le Saline is ranked highly by Expedia customers. This B&B offers free breakfast and free parking. Reviews from our site also recommend Palazzo Gilistro and Giuggiulena Villa as top options for your stay. See all available top hotels, or vacation rentals in Syracuse.

Ortigia is a culturally-rich neighborhood known for its lovely seaside views and interesting historical sites. Other favorite areas in Syracuse include Santa Lucia and Tiche.

What's the top vacation rental in Syracuse?

CORTILE DAVÌ - Ortigia Wifi Apartment: This highly rated vacation home rental in Syracuse is located by the ocean and offers a patio, air-conditioning, and laundry facilities to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. Some other top choices in Syracuse are Beach house/villa in Fontane Bianche, Syracuse, directly by the sea with Jacuzzi and House with private tennis court, pool, 300m to the beach, WiFi, air conditioning. See all vacation rentals in Syracuse.

If I need to cancel my hotel reservation in Syracuse, will I receive a refund?

Yes! Most hotel reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of check in. If you have a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Syracuse.

Where can I learn more about changing or cancelling my trip to Syracuse?

For additional details about picking new dates or cancelling your trip to Syracuse, click here.

What's the best accommodation for a budget-friendly stay in Syracuse?

Based on our traveler reviews, LoL Hostel Siracusa is a top choice for a less expensive stay. View all budget hotels in Syracuse.

What's the best hotel for a stay in Ortigia?

With 349 hotels and other accommodations to choose from in this neighborhood, you're sure to find what you're looking for as you plan your trip. Based on Expedia customer reviews, B&B La Via della Giudecca is the highest ranked property in Ortigia. This 3-star B&B offers free breakfast and free WiFi. It is located a short 4-minute walk from Cathedral of Syracuse. Other favorite options in the area include Algila' Ortigia Charme Hotel and Allegroitalia Siracusa Ortigia.

What's the best accommodation in Santa Lucia?

In this neighborhood, there are 134 places to stay, so you should find the perfect accommodation for your trip. B&B Vergilia is a favorite with our customers staying in Santa Lucia. This B&B is a short 4-minute walk from Museo Archeologico Regionale Paolo Orsi, and it offers free WiFi and comfy beds. Travelers also recommend Giuggiulena Villa and B&B Nostos as top options in the area.

What's the best place to stay for a family vacation in Syracuse?

Algila' Ortigia Charme Hotel is a hotel with a restaurant and free breakfast, and it's a top choice on Expedia for families. Other good choices for your stay with the kids include VOI Arenella Resort and Mercure Siracusa Prometeo. Attractions like Arkimedeion Museum and Museum of the Sea of Syracuse are also fun for kids of all ages. Find more child-friendly accommodations in Syracuse.

What's the best accommodation for a romantic vacation in Syracuse?

"B&B" Casa D'Alleri "Quadruple room in a historic home in" Ortigia " is a favorite B&B for couples, and features private balconies and flat-screen TVs. Other good choices for your romantic getaway include B&B Casa D'Alleri Triple Room and "B&B Casa D'Alleri" Double Rooms in a historic home in "Ortigia". See all romantic hotels in Syracuse.

What's the best LGBTQ-friendly hotel in Syracuse?

Mercure Siracusa Prometeo is a top LGBTQ-friendly hotel, and features a full-service spa and free WiFi. Residence Archimede and Dimora Caiammari Luxury Hotel & Spa are two other good choices for your vacation. See all available hotels listed as LGBTQ-friendly in Syracuse.

What's the best pet-friendly accommodation in Syracuse?

Palazzo Artemide - VRetreats is a top hotel for people traveling with their pets, and offers a restaurant and a bar/lounge for its human guests. Other good options for you and your pet's trip include Maniace Boutique Hotel Ortigia UNA Esperienze and Ortea Palace Hotel, Sicily, Autograph Collection. See more pet-friendly hotel accommodations in Syracuse.

Where is the best hotel to stay near Lungomare di Ortigia?

Adjacent to Lungomare di Ortigia, Algila' Ortigia Charme Hotel is one of the top choices for your stay based on our traveler data, and this 4-star hotel offers 2 bars and free breakfast. Other good choices close by include Caportigia Boutique Hotel and Grand Hotel Ortigia Siracusa.

What about the best place to stay near Porto Piccolo?

One of the top choices for your stay is Caportigia Boutique Hotel, located next to Porto Piccolo, and this 5-star property offers a restaurant and free parking. Algila' Ortigia Charme Hotel and Ortea Palace Luxury Hotel are two other good choices in the immediate area.

What's the best place to stay near the beach in Syracuse?

VOI Arenella Resort is a top beachfront hotel with 2 outdoor pools and 3 restaurants, and it's located close to Spiaggia dell'Arenella. Other good options for your stay near the beach include Maniace Boutique Hotel Ortigia UNA Esperienze and Residence Archimede. See more stays near the beach in Syracuse.

What's the best luxury accommodation in Syracuse?

Wellness & Spa Hotel Principe di Fitalia is a luxury hotel with a winery and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Grand Hotel Ortigia Siracusa and Minareto are other upscale choices for your vacation. Find more luxury hotels in Syracuse.

What's the best boutique-style hotel in Syracuse?

Charme Hotel Henry's House is a favorite hotel with our travelers looking for a stylish accommodation, and features 14 guestrooms, free breakfast, and a rooftop terrace. See all boutique hotels in Syracuse.

What's the best hotel in Syracuse to learn about local history?

Based on our travel expertise, "B&B" Casa D'Alleri "Quadruple room in a historic home in" Ortigia " is a top B&B on Expedia for those interested in history, and it features free breakfast and free WiFi. A couple of other options near historic sites include B&B Casa D'Alleri Triple Room and "B&B Casa D'Alleri" Double Rooms in a historic home in "Ortigia". Also notable landmarks to visit include Temple of Apollo, Piazza del Duomo, and Cathedral of Syracuse. See more options for historical stays in Syracuse.

What's the best part of Syracuse for seeing the sights?

Santa Lucia is one of the best areas of the city for sightseeing so consider a stop by Porto Piccolo, Madonna delle Lacrime, and Papyrus Museum while you're exploring the neighborhood. Another popular neighborhood for sightseeing is Ortigia with 19 places to visit and top sights like Cathedral of Syracuse and Temple of Apollo.

What are some accommodations with pools in Syracuse?

Minareto is a top hotel with an outdoor pool, a full-service spa, and free buffet breakfast. A couple of other options with an onsite pool include Eureka Palace Hotel Spa Resort and Domus Mariae Benessere. View all hotels with pools in Syracuse.

What is the best spa hotel in Syracuse?

VOI Arenella Resort is a top beachfront spa hotel featuring 3 restaurants, a fitness center, tennis courts, and a hair salon. Enjoy a facial, body treatment, or massage at the onsite spa. Other popular spa hotels in Syracuse include Ortea Palace Hotel, Sicily, Autograph Collection and Mercure Siracusa Prometeo. See all spa hotels in Syracuse.

What's the most popular hotel in Syracuse with an on-site water park or a water park nearby?

Private room on Sicilian garden,10 min from beaches is a popular B&B featuring water park access, an outdoor pool, and in-room kitchens. You'll find Aretusa Park within 11 minutes by car. Check out all hotels with or near waterparks in Syracuse.

What is the best hotel near Fontanarossa Airport (CTA)?

Catania International Airport Hotel is a popular 4-star hotel featuring a roundtrip airport shuttle and an airport shuttle. It's located a short 0.7 mi (1.2 km) from Fontanarossa Airport. Other choices close to the airport are NH Catania Parco Degli Aragonesi and Romano Palace Luxury Hotel.

What's it like to stay in Syracuse?

History buffs will enjoy exploring Syracuse, and visitors give high marks for the seaside. Culturally rich and walkable, this city will delight tourists with its cafes, archaeological sites, and cathedral. In Syracuse, there are 2092 hotels and other accommodations to choose from. Find out more about Syracuse.

What is there to see in Syracuse?

Cultural venues include Arkimedeion Museum, Teatro dei Pupi, and Syracuse Municipal Theater. Notable for its historic sites, landmarks like Temple of Apollo, Piazza del Duomo, and Cathedral of Syracuse are not to be missed. The natural setting is picturesque, namely the breathtaking ocean views, and these places to see: Ear of Dionysius, Spiaggia del Minareto, and Fanusa Beach. Check out what more to see and do in Expedia's Syracuse guide.

What's the best way to get around Syracuse?

To see more of the surrounding area, ride one of the trains from Syracuse Station or Targia Station. If you want to venture out around the area, you may want a rental car in Syracuse for your journey.

What's the seasonal weather like in Syracuse?

The hottest months are usually August and July with an average temp of 78°F, while the coldest months are February and January with an average of 56°F. Average annual precipitation for Syracuse is 26 inches.