Find 5 Star Hotels in Syracuse from AED 346

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Check availability on Syracuse 5 Star Hotels

Compare Syracuse 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Algila' Ortigia Charme Hotel
Front of property - evening/night

Algila' Ortigia Charme Hotel

4.0 star property
9.6 out of 10, Exceptional, (791)
"Comfort room was too small, especially the bathroom and very hot and humid, although not warm outside. Dust under the window borders and the bed, a lot. Sink drain was rusted and foam was coming out."
The price is AED 663
AED 769 total
includes taxes & fees
15 Mar - 16 Mar
Algila' Ortigia Charme Hotel
Ortea Palace Hotel, Sicily, Autograph Collection
Front of property - evening/night

Ortea Palace Hotel, Sicily, Autograph Collection

5.0 star property
9.4 out of 10, Exceptional, (227)
"Hotel was absolutely beautiful! Perfect location. Staff was very friendly and professional. Drinks & dining fantastic. Can not wait to visit again nect year! Thank you again. With sincere wishes Joe & Edie Hayes"
The price is AED 837
AED 960 total
includes taxes & fees
12 Mar - 13 Mar
Ortea Palace Hotel, Sicily, Autograph Collection
Mercure Siracusa Prometeo
Terrace/patio

Mercure Siracusa Prometeo

4.0 star property
9.0 out of 10, Wonderful, (443)
"N/A"
The price is AED 346
AED 420 total
includes taxes & fees
27 Mar - 28 Mar
Mercure Siracusa Prometeo
VOI Arenella Resort
Private beach, free beach shuttle, sun loungers, beach umbrellas

VOI Arenella Resort

4.0 star property
8.0 out of 10, Very Good, (117)
"It would be great to have hair conditioner in the room. Beautiful grounds and the beach and swim platforms were beautiful. "
VOI Arenella Resort
Grand Hotel Des Ètrangers
Seasonal outdoor pool, pool umbrellas, sun loungers

Grand Hotel Des Ètrangers

5.0 star property
9.4 out of 10, Exceptional, (37)
"This hotel as well as the entire Ortiga area was an absolute delight! It was a our first visit to Sicily and we were in love the minute our driver dropped ud off!"
Grand Hotel Des Ètrangers
Grand Hotel Ortigia Siracusa
Aerial view

Grand Hotel Ortigia Siracusa

5.0 star property
9.0 out of 10, Wonderful, (535)
"A lovely place, with fantastic staff, very polite and helpful. "
The price is AED 723
AED 836 total
includes taxes & fees
24 Mar - 25 Mar
Grand Hotel Ortigia Siracusa
Maniace Boutique Hotel Ortigia UNA Esperienze
Front of property

Maniace Boutique Hotel Ortigia UNA Esperienze

10.0 out of 10, Exceptional, (4)
"Amazing hotel, super comfortable room! Spetacular view! I would definitely stay again!"
The price is AED 753
AED 868 total
includes taxes & fees
20 Mar - 21 Mar
Maniace Boutique Hotel Ortigia UNA Esperienze
Grand Hotel Villa Politi
Seasonal outdoor pool

Grand Hotel Villa Politi

4.0 star property
8.6 out of 10, Excellent, (890)
"Daily room cleaning and fresh towels. Good breakfast. Disposable slippers. Could've better if a coffee machine is provided."
The price is AED 374
AED 451 total
includes taxes & fees
13 Mar - 14 Mar
Grand Hotel Villa Politi
Palazzo Artemide - VRetreats
Reception

Palazzo Artemide - VRetreats

4.0 star property
9.4 out of 10, Exceptional, (620)
"Simple elegance, well decorated small Hotel with friendly staff, Roberto at the front desk was great, so friendly and helpful, Thanks!!! Highly recommend the hotel!!! "
The price is AED 609
AED 710 total
includes taxes & fees
16 Mar - 17 Mar
Palazzo Artemide - VRetreats
Charme Hotel Henry's House
Exterior

Charme Hotel Henry's House

4.0 star property
9.6 out of 10, Exceptional, (284)
"Amazing, eclectic, hotel. The photos do not do it justice. Friendly, helpful, staff. The breakfast was delicious with a lot of variety. Everything about this place will make you feel special. "
The price is AED 660
AED 766 total
includes taxes & fees
14 Mar - 15 Mar
Charme Hotel Henry's House
Domus Mariae Albergo
Exterior

Domus Mariae Albergo

3.0 star property
9.2 out of 10, Wonderful, (278)
"This was the most incredible hospitality experience I have ever had. The staff here is genuinely nice and kind. So happy I chose to stay here for the weekend."
The price is AED 785
AED 904 total
includes taxes & fees
13 Mar - 14 Mar
Domus Mariae Albergo
Hotel Palazzo Cavalieri
Suite | Soundproofing, free WiFi

Hotel Palazzo Cavalieri

4.0 star property
9.6 out of 10, Exceptional, (11)
"Struttura situata in posizione ideale per visitare Siracusa e Ortigia. Personale gentile e accogliente. Camera spaziosa e luminosa, letto confortevole, pulizia impeccabile. Buona la colazione, varia e abbondante. Ottimo rapporto qualità prezzo. Consigliato"
The price is AED 385
AED 463 total
includes taxes & fees
17 Mar - 18 Mar
Hotel Palazzo Cavalieri
Palazzo Gilistro
Rooftop terrace

Palazzo Gilistro

9.8 out of 10, Exceptional, (120)
"Excellent location in the heart of Ortigia. Very friendly and responsive staff. Good breakfast with plenty of offerings. Lovely terrace overlooking one of the busy streets. Parking is best done by valet at 30 Euros/day but works very well. "
The price is AED 711
AED 822 total
includes taxes & fees
11 Apr - 12 Apr
Palazzo Gilistro
Residence Archimede
Seasonal outdoor pool, pool umbrellas, sun loungers

Residence Archimede

4.0 star property
8.6 out of 10, Excellent, (7)
"It was super quite and beautiful. It was great for the kids."
The price is AED 423
AED 483 total
includes taxes & fees
4 Apr - 5 Apr
Residence Archimede
UNAHOTELS One Siracusa
Pool

UNAHOTELS One Siracusa

4.0 star property
8.6 out of 10, Excellent, (513)
"Haverting "
The price is AED 460
AED 545 total
includes taxes & fees
16 Mar - 17 Mar
UNAHOTELS One Siracusa
Eureka Palace Hotel Spa Resort
Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers

Eureka Palace Hotel Spa Resort

4.0 star property
8.0 out of 10, Very Good, (279)
"Extremely nice hotel. Especially after a long drive. Pool was beautiful and staff very helpful. Highly recommend. Good price. "
The price is AED 355
AED 430 total
includes taxes & fees
22 Mar - 23 Mar
Eureka Palace Hotel Spa Resort
Lanterne Magiche Ortigia
Panoramic Studio, 1 Double Bed, Sea View | Terrace/patio

Lanterne Magiche Ortigia

9.4 out of 10, Exceptional, (119)
"Great place. Excellent location. Prompt service response when we had a ce problem with the shower. Very good breakfast. "
The price is AED 329
AED 402 total
includes taxes & fees
12 Mar - 13 Mar
Lanterne Magiche Ortigia
Wellness & Spa Hotel Principe di Fitalia
Sports facility

Wellness & Spa Hotel Principe di Fitalia

5.0 star property
9.6 out of 10, Exceptional, (81)
"Wonderful top service hotel on our trip to Sicily. Couldn’t ask for more as they did everything possible to make sure our stay was enjoyable Great hospitality at it’s best "
The price is AED 1,226
AED 1,388 total
includes taxes & fees
13 Mar - 14 Mar
Wellness & Spa Hotel Principe di Fitalia
Minareto
Private beach nearby, sun loungers, beach umbrellas, beach towels

Minareto

5.0 star property
8.8 out of 10, Excellent, (254)
"Beautiful natural settings . Gorgeous views "
Minareto
Caportigia Boutique Hotel
Rooftop terrace

Caportigia Boutique Hotel

5.0 star property
9.4 out of 10, Exceptional, (224)
"This is a chic, well-appointed hotel with charming rooms in a central location in Syracuse -- situated between the enormous Greek ruins and the charming old Roman section of Ortigia. The rooms are clean and elegant, with creative decor, comfortable beds, and modern bathrooms. The lobby is bright and cheerful. The attached dining area is large and airy, offering a large, many-option and reasonably-priced buffet breakfast. The staff are kind and helpful. My only suggestion to the hotel is to...
The price is AED 470
AED 557 total
includes taxes & fees
24 Mar - 25 Mar
Caportigia Boutique Hotel
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Syracuse.
Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

Via Vittorio Veneto 93, Syracuse, SR
The price is AED 663 per night from Mar 15 to Mar 16
AED 663
AED 769 total
includes taxes & fees
15 Mar - 16 Mar
9.4/10 Exceptional! (784 reviews)
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Frequently asked questions

What are the best 5-star hotels in Syracuse?
Prepare for 5-star opulence at Grand Hotel Ortigia Siracusa, Ortea Palace, Sicily, Autograph Collection or Grand Hotel Des Ètrangers. These are some of the best stays in Syracuse based on Expedia customer reviews. Book one and get a taste of the finer life!
How much does it cost to stay in a 5-star hotel in Syracuse?
How much you pay for a 5-star hotel in Syracuse depends on factors like when you plan to go and the length of your vacation. Our insider tip for bagging the best deal? Use our pricing filters to compare all of the available hotels for your preferred dates.

  • Search for the lowest price per night from AED 346

What makes a hotel 5 stars in Syracuse?
From high-end restaurants and fitness centers to swimming pools and superior bedding, the 5-star experience in Syracuse is all about luxury and relaxation. But it calls for more than just upscale amenities to get a 5-star rating. Hotels also have to deliver outstanding guest services like massage treatments, laundry and dry cleaning and 24-hour room service.
Are there any 5-star all-inclusive resorts in Syracuse?
Our filter tool is the easiest way to find exactly what you want. Select “5-star” and “All inclusive” to show the most luxurious properties in Syracuse where your accommodations, meals, activities and entertainment are included in the price. At these retreats, your vacation is pure extravagance from the moment you check in.
What are the top 5-star spa hotels in Syracuse?
Syracuse has a range of 5-star spa accommodations that offer therapies designed to revitalize both the mind and body. Spend your next vacation at Minareto, Ortea Palace, Sicily, Autograph Collection or Grand Hotel Ortigia Siracusa and prioritize your health and well-being.
Are there any 5-star vacation rentals in Syracuse?
You won’t find any 5-star vacation rentals in Syracuse on our site, but there are a few other highly rated properties worth checking out. Browse our vacation rentals in Syracuse to book the perfect place for your stay.
Are there any 5-star hotels in downtown Syracuse?
Book a room at Grand Hotel Ortigia Siracusa. This 5-star hotel is an excellent option if you want to experience Syracuse’s exciting downtown scene.