Find 5 Star Hotels in Syracuse from AED 334

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Compare Syracuse 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Ortea Palace Hotel, Sicily, Autograph Collection

5.0 star property
9.4 out of 10, Exceptional, (226)
"Great place and staff. We definitely are going back there, next time in Sicily "
The price is AED 662
AED 766 total
includes taxes & fees
3 Feb - 4 Feb
Ortea Palace Hotel, Sicily, Autograph Collection

Grand Hotel Ortigia Siracusa

5.0 star property
9.0 out of 10, Wonderful, (534)
"A lovely place, with fantastic staff, very polite and helpful. "
The price is AED 692
AED 799 total
includes taxes & fees
3 Feb - 4 Feb
Grand Hotel Ortigia Siracusa

Caportigia Boutique Hotel

5.0 star property
9.4 out of 10, Exceptional, (221)
"It is excellent hotel, highly recommended "
The price is AED 379
AED 455 total
includes taxes & fees
8 Feb - 9 Feb
Caportigia Boutique Hotel

Grand Hotel Des Ètrangers

5.0 star property
9.4 out of 10, Exceptional, (37)
"This hotel as well as the entire Ortiga area was an absolute delight! It was a our first visit to Sicily and we were in love the minute our driver dropped ud off!"
Grand Hotel Des Ètrangers

Minareto

5.0 star property
8.8 out of 10, Excellent, (254)
"Beautiful natural settings . Gorgeous views "
Minareto

Borgo di Luce - I Monasteri Golf Resort & SPA

5.0 star property
7.0 out of 10, Good, (25)
"Great rooms. Updated and modern. Staff was terrific . It’s little out of the way from town . Dark roads. The breakfast was great. Would definitely come back . "
Borgo di Luce - I Monasteri Golf Resort & SPA

Wellness & Spa Hotel Principe di Fitalia

5.0 star property
9.6 out of 10, Exceptional, (81)
"Wonderful top service hotel on our trip to Sicily. Couldn’t ask for more as they did everything possible to make sure our stay was enjoyable Great hospitality at it’s best "
Wellness & Spa Hotel Principe di Fitalia

Dimora Caiammari Luxury Hotel & Spa

5.0 star property
9.2 out of 10, Wonderful, (198)
"The moment we checked in we knew we were in good hands, the manager and his wife greeted us with a warm, professional and friendly welcome . The hotel is beautiful and very clean. Every ! staff member was helpful, professional and friendly. Our room was very cleaned, quiet and large. Decorated simple clean lines, king bed was comfortable and all the linens were lovely.Two pools huge garden with paths to walk around, Hotel was a great location to drive our rental car to Syracuse and Isola Di...
Dimora Caiammari Luxury Hotel & Spa
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the best 5-star hotels in Syracuse?
Prepare for 5-star opulence at Grand Hotel Ortigia Siracusa, Ortea Palace, Sicily, Autograph Collection or Grand Hotel Des Ètrangers. These are some of the best stays in Syracuse based on Expedia customer reviews. Book one and get a taste of the finer life!
How much does it cost to stay in a 5-star hotel in Syracuse?
How much you pay for a 5-star hotel in Syracuse depends on factors like when you plan to go and the length of your vacation. Our insider tip for bagging the best deal? Use our pricing filters to compare all of the available hotels for your preferred dates.

  • Search for the lowest price per night from AED 334

What makes a hotel 5 stars in Syracuse?
From high-end restaurants and fitness centers to swimming pools and superior bedding, the 5-star experience in Syracuse is all about luxury and relaxation. But it calls for more than just upscale amenities to get a 5-star rating. Hotels also have to deliver outstanding guest services like massage treatments, laundry and dry cleaning and 24-hour room service.
Are there any 5-star all-inclusive resorts in Syracuse?
Our filter tool is the easiest way to find exactly what you want. Select “5-star” and “All inclusive” to show the most luxurious properties in Syracuse where your accommodations, meals, activities and entertainment are included in the price. At these retreats, your vacation is pure extravagance from the moment you check in.
What are the top 5-star spa hotels in Syracuse?
Syracuse has a range of 5-star spa accommodations that offer therapies designed to revitalize both the mind and body. Spend your next vacation at Minareto, Ortea Palace, Sicily, Autograph Collection or Grand Hotel Ortigia Siracusa and prioritize your health and well-being.
Are there any 5-star vacation rentals in Syracuse?
You won’t find any 5-star vacation rentals in Syracuse on our site, but there are a few other highly rated properties worth checking out. Browse our vacation rentals in Syracuse to book the perfect place for your stay.
Are there any 5-star hotels in downtown Syracuse?
Book a room at Grand Hotel Ortigia Siracusa. This 5-star hotel is an excellent option if you want to experience Syracuse’s exciting downtown scene.