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Compare 154 Vacation Homes in St. Charles with updated reviews, rates, and availability.

☆Dee Dee's Den: A Dharma Dwellings Parent Company☆
Welcome to Dee Dee's Den! We are pleased to offer this home for you!

☆Dee Dee's Den: A Dharma Dwellings Parent Company☆

10.0 out of 10, Exceptional, (27)
"House looks small on outside but inside is spacious and nicely decorated. Neighborhood is quiet and near Silver Lake, which is a nice walk. House was clean and had everything needed for a comfortable stay."
☆Dee Dee's Den: A Dharma Dwellings Parent Company☆
Great Family Home, Fenced Yard, Pet Friendly, 2 mi from Mayo
Living area

Great Family Home, Fenced Yard, Pet Friendly, 2 mi from Mayo

10.0 out of 10, Exceptional, (34)
"Our stay was great. The house is larger than the pictures convey. It has everything you need. Lots of linens, kitchen was well stocked. Large backyard (we didn't use as the weather was quite wet and the time of year). Floor is a little creaky, but that's just the age of the house. We will definitely book here again. The owner was very responsive in communication, though we didn't need anything."
Great Family Home, Fenced Yard, Pet Friendly, 2 mi from Mayo
Charming Brick Farmhouse with a Touch of Elegance. -Winona
Welcome to the Village House Inn. Whole house vacation rental.

Charming Brick Farmhouse with a Touch of Elegance. -Winona

10.0 out of 10, Exceptional, (120)
"Our family stayed at the Village House Inn over Christmas and it was perfect for accommodating a large group very comfortably. The location and proximity to Winona was also ideal. We will definitely be back! "
The price is AED 1,065
AED 1,759 total
includes taxes & fees
12 Jan - 13 Jan
Charming Brick Farmhouse with a Touch of Elegance. -Winona
Charming 3-bedroom, 2 bathroom house with outdoor space in Winona
Exterior

Charming 3-bedroom, 2 bathroom house with outdoor space in Winona

10.0 out of 10, Exceptional, (11)
"the inside was beautiful. the neighborhood was decent and quiet. very comfortable stay!"
The price is AED 863
AED 1,045 total
includes taxes & fees
12 Jan - 13 Jan
Charming 3-bedroom, 2 bathroom house with outdoor space in Winona
Sunrise on Skyline - Indoor Pool - Arcades - Amazing Views!
You'll have endless fun in our endless pool! Overlooks the Mississippi River!

Sunrise on Skyline - Indoor Pool - Arcades - Amazing Views!

10.0 out of 10, Exceptional, (64)
"The place was wonderful! Pool was very clean and nice! The reason I gave only 4 stars on cleanliness is that the cleaners need to move the furniture and sweep- we cleaned up stuff that wasn’t ours. We would definitely stay again and tell others about this place! The views are so beautiful!!! Thank you so much!!"
Sunrise on Skyline - Indoor Pool - Arcades - Amazing Views!
1 mi. from Mayo Clinic; Cozy, Clean

1 mi. from Mayo Clinic; Cozy, Clean

9.6 out of 10, Exceptional, (85)
"We enjoyed our stay. We were in Rochester for a family reunion, so spent a lot of time away from this house. We have a couple of safety issues that should be addressed. First is a railing of some kind at the entrance. My husband and I are both in our 80s and could have felt safer with a railing to help us enter and exit the house. The other issue was there no safety bars in the tub/shower in the upstairs bathroom. "
1 mi. from Mayo Clinic; Cozy, Clean
Charming 2 Bed 1 Bath Home W/Fully Fenced in Back yard
Living area

Charming 2 Bed 1 Bath Home W/Fully Fenced in Back yard

9.4 out of 10, Exceptional, (13)
"Everything was excellent! Super happy"
The price is AED 356
AED 1,011 total
includes taxes & fees
12 Jan - 13 Jan
Charming 2 Bed 1 Bath Home W/Fully Fenced in Back yard
The Broadway Exchange
Bathroom

The Broadway Exchange

9.8 out of 10, Exceptional, (20)
"This was our third stay and we love this location. Really appreciated the holiday decorating at the residence. We love this house and it is close to locations we like to frequent. Thank you!"
The Broadway Exchange
Family friendly in the peaceful heart of town
Kitchen. Ladder can be removed. Everyday needs are easily in reach on shelves.

Family friendly in the peaceful heart of town

10.0 out of 10, Exceptional, (88)
"Beautiful house, close to the lake. Had everything you could need."
Family friendly in the peaceful heart of town
Your Stay Steps Away - 709 Mayo Discount!
Living area

Your Stay Steps Away - 709 Mayo Discount!

10.0 out of 10, Exceptional, (23)
"It was clean with a well-stocked kitchen. It was easy to enter. The host was available immediately when we had a question. We could easily adjust the heat and cooling. It was a very enjoyable stay."
Your Stay Steps Away - 709 Mayo Discount!
☆Oakley's Oasis, a Dharma Dwellings Designed Home☆
Welcome to Oakley's Oasis! We look forward to hosting you!

☆Oakley's Oasis, a Dharma Dwellings Designed Home☆

10.0 out of 10, Exceptional, (29)
"Overall a comfy, cozy stay. Would consider returning with the only issue being we wish there was a king bed. The queen was a bit too cramped to be comfy."
☆Oakley's Oasis, a Dharma Dwellings Designed Home☆
3 miles to Mayo, Four bed home, Covered By Faith
Front of house from street

3 miles to Mayo, Four bed home, Covered By Faith

2.0 star property
6.0 out of 10, (1)
3 miles to Mayo, Four bed home, Covered By Faith
Coratel Inn & Suites by Jasper Rochester-2 Queen Bed Non Smoking
Room

Coratel Inn & Suites by Jasper Rochester-2 Queen Bed Non Smoking

The price is AED 253
AED 376 total
includes taxes & fees
12 Jan - 13 Jan
Coratel Inn & Suites by Jasper Rochester-2 Queen Bed Non Smoking
City Hall Recorder's Office
Living Area

City Hall Recorder's Office

2.0 star property
10.0 out of 10, Exceptional, (4)
"Property is just as stated and was n walking distance to Mayo and places to eat. The apartment had everything someone would need. Management sent good efficient communication regarding check in and out process."
The price is AED 342
AED 837 total
includes taxes & fees
1 Feb - 2 Feb
City Hall Recorder's Office
The River Cabin Summ

The River Cabin Summ

10.0 out of 10, Exceptional, (8)
"It was just beautiful!"
The River Cabin Summ
Elegant & Secure Family Abode Grand 4-Bedroom Retreat (Entire House)
Exterior

Elegant & Secure Family Abode Grand 4-Bedroom Retreat (Entire House)

10.0 out of 10, Exceptional, (3)
"We stayed for 5 nights for our sons wedding. Everything was as described and worked well for us. Very reasonable price and had 0 problems. Very comfortable and even had our own garage door opener. "
Elegant & Secure Family Abode Grand 4-Bedroom Retreat (Entire House)
Lost Creek Executive Home on 200 acre horse Ranch w/Trout Stream
Property grounds

Lost Creek Executive Home on 200 acre horse Ranch w/Trout Stream

9.8 out of 10, Exceptional, (6)
"This home was AMAZING and there was so much space. If it had more Beds, Futons or Couches available for LARGE GROUPS it could really bring in the bigger groups since the Mayo Civic Center is only 20 Minutes away. If you are looking for a great accommodating host and an amazing property...LOK NO FURTHER."
Lost Creek Executive Home on 200 acre horse Ranch w/Trout Stream
BIG Discount! Five Star-3 Bedroom Showstopper 4 Minutes to Mayo Clinic!
Relax in our stylishly decorated living room.

BIG Discount! Five Star-3 Bedroom Showstopper 4 Minutes to Mayo Clinic!

9.6 out of 10, Exceptional, (10)
"We celebrated our family “Thanksmas” with my daughter’s uncle and his family here. It was a very quick trip but the layout of the house with the three bedrooms, generous kitchen and dining table were perfect for our needs. The 2-year old especially was enamored with the numerous toys provided and the older girls were able to do lots of crafts and games at the dining table. As the oldest adult, I appreciated the comfort of the bed and how clean and organized the entire place was. The little...
BIG Discount! Five Star-3 Bedroom Showstopper 4 Minutes to Mayo Clinic!
Within walking distance of all the amenities! Bike the trail~ float the river
Exterior

Within walking distance of all the amenities! Bike the trail~ float the river

10.0 out of 10, Exceptional, (10)
"The house was great! Kitchen is well stocked and we felt right at home. We would love to come back again!"
Within walking distance of all the amenities! Bike the trail~ float the river
Park in the Garage and Walk to Mayo Clinic
King size bed with memory foam mattress in primary bedroom located upstairs.

Park in the Garage and Walk to Mayo Clinic

10.0 out of 10, Exceptional, (53)
"Have had to come up to Mayo twice for appointments and stayed here both times. Place makes you feel at home very comfortable and cozy. Large kitchen plenty of space. Bed is amazing and cozy. Host was easy to communicate with and very nice. "
Park in the Garage and Walk to Mayo Clinic
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in St. Charles

The Berkman
Lobby

The Berkman

3.0 star property
9.6 out of 10, Exceptional, (261)
"Love having a little apartment. Quiet too, nice gym and sauna"
The price is AED 651
AED 757 total
includes taxes & fees
12 Jan - 13 Jan
The Berkman
Heritage hideaway-Secluded Log Cabin
Property grounds

Heritage hideaway-Secluded Log Cabin

10.0 out of 10, Exceptional, (361)
"It was a great stay. Best stay iv had using Vrbo. The property is perfect. "
Heritage hideaway-Secluded Log Cabin
Broadway Plaza, Trademark Collection by Wyndham
Room

Broadway Plaza, Trademark Collection by Wyndham

3.0 star property
9.2 out of 10, Wonderful, (147)
"Very good"
Broadway Plaza, Trademark Collection by Wyndham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.