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Compare 328 Vacation Homes in Southern Minnesota with updated reviews, rates, and availability.

Experience the ultimate riverside retreat at our charming river cabin.
Nice size living room with amazing views of the Mississippi River
Experience the ultimate riverside retreat at our charming river cabin.
10.0 out of 10, Exceptional, (4)
"Beautiful views! The cabin was very comfortable and had everything we needed. Highly recommended! :)"
Experience the ultimate riverside retreat at our charming river cabin.
Fantastic Large Home Right On Beautiful Lake Pepin!
view of the lake from the chaise lounges
Fantastic Large Home Right On Beautiful Lake Pepin!
10.0 out of 10, Exceptional, (207)
"Wonderful time. Nice home. Enjoyed the area, nice big table and fire pit."
Fantastic Large Home Right On Beautiful Lake Pepin!
Silver Lake Oasis
Silver Lake Oasis
Silver Lake Oasis
9.6 out of 10, Exceptional, (30)
"Stayed 3 nights for tests at Mayo. Good location. Quick drive to hospital. Nice two mile walk around Silver Lake. The house had everything we needed and was very comfy, except for the tv positioning. Hard to see from the couch. "
Silver Lake Oasis
Charming 3-bedroom, 2 bathroom house with outdoor space in Winona
Exterior
Charming 3-bedroom, 2 bathroom house with outdoor space in Winona
9.8 out of 10, Exceptional, (8)
"Perfect place right in town!"
The price is AED 826
AED 1,014 total
includes taxes & fees
30 Sep - 1 Oct
Charming 3-bedroom, 2 bathroom house with outdoor space in Winona
Sunrise on Skyline - Indoor Pool - Arcades - Amazing Views!
You'll have endless fun in our endless pool! Overlooks the Mississippi River!
Sunrise on Skyline - Indoor Pool - Arcades - Amazing Views!
10.0 out of 10, Exceptional, (58)
"My group was amazed with the house from the minute we pulled up. The views are stunning, the house was very clean, and was set up with everything we needed. The layout is incredibly unique, and we enjoyed spending time wondering around to find everything we had seen in the pictures. We had a minor issue with the door lock one day, but the host answered my call immediately and resolved the situation in a matter of minutes. We had someone in our group with some mobility issues so I will note...
Sunrise on Skyline - Indoor Pool - Arcades - Amazing Views!
The Hen House Retreat - A Comfortable Place to Roost
Beautiful flowers and local limestone rock make this a great place to enjoy.
The Hen House Retreat - A Comfortable Place to Roost
9.8 out of 10, Exceptional, (71)
"Very nice clean house. Wish we could have stayed longer. Plenty of room for everyone. "
The price is AED 661
AED 812 total
includes taxes & fees
29 Sep - 30 Sep
The Hen House Retreat - A Comfortable Place to Roost
Euro House, Spacious! Near Mayo-Private Home
Open concept, architecturally pleasing, soft and modern roomy home.
Euro House, Spacious! Near Mayo-Private Home
10.0 out of 10, Exceptional, (27)
"This house is absolutely the most unique property I have found in the Rochester area. The property is spacious, immaculate, centrally-located and has so much character. Our family gathered in the large interior space for meals but, the outdoor garden was the spot we especially enjoyed for morning coffee and evening conversations. The home is located near a local bike/walking trail so, getting in my daily exercise was so convenient. Malea was always quick to respond to any questions. I...
Euro House, Spacious! Near Mayo-Private Home
Country Charm Over River Valley And Horse Farm
Kitchen with large island
Country Charm Over River Valley And Horse Farm
10.0 out of 10, Exceptional, (31)
"We had a fantastic time here in La Crescent. 9 of us men had plenty of room and the house and property were very clean. The host was very communicative and answered any questions we had. I would recommend this for anyone!"
Country Charm Over River Valley And Horse Farm
Victorian era Mississippi riverview retreat.
Property grounds
Victorian era Mississippi riverview retreat.
9.6 out of 10, Exceptional, (22)
"This house was great! We were down to visit my son at Winona State University for the weekend. Fountain City was the perfect cute little river town and it was a short drive away. The house was cozy, clean, quiet, and well stocked. Beds were very comfortable and the host is very accomodating and always seeking to improve, which shows great character. We will definitely stay again! "
Victorian era Mississippi riverview retreat.
Family friendly in the peaceful heart of town
Kitchen. Ladder can be removed. Everyday needs are easily in reach on shelves.
Family friendly in the peaceful heart of town
10.0 out of 10, Exceptional, (81)
"When we first walked into the place and fumbled for a light switch, we saw a marvelous kitchen where everything had a descriptive label. We were quickly able to bypass the usual "Hey, where are the silverware?" complications immediately. Multi-switch panels are also clearly labeled as to their function. Convenient! During the first afternoon we were there heavy rain came through while we were watching TV in the front room. We didn't notice the rain until someone got up to see it out the...
Family friendly in the peaceful heart of town
Quaint Boutique Home *NEAR MAYO*
Dining
Quaint Boutique Home *NEAR MAYO*
9.6 out of 10, Exceptional, (37)
"This is a great location to stay because it is convenient to Mayo, and also close to a lot of areas to get food And groceries."
Quaint Boutique Home *NEAR MAYO*
St. Augustine's Restful Heart House WALK to St. Mary's
Cable, smart tv, fast wifi
St. Augustine's Restful Heart House WALK to St. Mary's
10.0 out of 10, Exceptional, (38)
"The house was the perfect place while we had appointments at Mayo. It was very clean and stocked with all the essentials. The owner was very accessible by text when I had questions. It’s an easy walk to St. Mary’s where you can catch the shuttle to the other Mayo buildings."
St. Augustine's Restful Heart House WALK to St. Mary's
-The Cotton House- Modern, Clean, Close to MSU!
Exterior
-The Cotton House- Modern, Clean, Close to MSU!
2.0 star property
10.0 out of 10, Exceptional, (4)
"Perfect location for our trade show at the Mayo Clinic Event Center. House is very clean and very safe neighborhood. Host was great and very attentive. We will be back for sure!"
The price is AED 547
AED 973 total
includes taxes & fees
30 Sep - 1 Oct
-The Cotton House- Modern, Clean, Close to MSU!
Century Cottage-PERFECT for Mayo & downtown visitors!
Cozy and spacious
Century Cottage-PERFECT for Mayo & downtown visitors!
10.0 out of 10, Exceptional, (96)
"This place had all we needed and more. It was very convenient to the Mayo Clinic in a nice quiet neighborhood. Good restaurants nearby and a nice park to walk to. The house was great and the chickens were fun to watch."
Century Cottage-PERFECT for Mayo & downtown visitors!
"Walden Pond" Adventure Amidst 44 Private Acres
Enjoy the comfort and beauty of the inside and the awesome adventure outside.
"Walden Pond" Adventure Amidst 44 Private Acres
10.0 out of 10, Exceptional, (114)
"Stayed 3 weeks. It was wonderful. Especially liked the trails for hiking with our dog. It was close to Rochester and Stewartville had a nice grocery called Fareway. Also had a good place for pizza called 2 Brothers. My son liked the proximity to Anytime Fitness too."
"Walden Pond" Adventure Amidst 44 Private Acres
Happy Days Log Home and garden on Fountain Lake. Toys for all!
Perennial garden attracts birds and butterflies. Veggie garden for picking!
Happy Days Log Home and garden on Fountain Lake. Toys for all!
10.0 out of 10, Exceptional, (29)
"Memories Galore - Great time had by everyone, peaceful location, in this comfortable gem on the river. Activities and toys for every age group, yet separate enough for those who want quiet time! Thank you for the hospitality! "
Happy Days Log Home and garden on Fountain Lake. Toys for all!
Mississippi River View with updated driveway
Mississippi River View with updated driveway
9.4 out of 10, Exceptional, (122)
"We enjoyed the impressive views and spending time on the screened-in porch. (The views are more impressive than the photos show, especially at sunset!) Kitchen was well stocked with cookware and other kitchen items. It's a beautiful and scenic drive along the river to get there. The driveway is very steep, but there are a few pull off spots next to the road for easier parking. Thanks for the wonderful stay!"
Mississippi River View with updated driveway
St. Augustine Mint House GARAGE!!
Beautifully remodeled kitchen with dishwasher!
St. Augustine Mint House GARAGE!!
10.0 out of 10, Exceptional, (59)
"This little house was just what my husband and I needed for our trip to Mayo. All the little homey touches that Denise has thought of made our anxiety ridden trip feel better. We’ll definitely look to stay at this property again. "
St. Augustine Mint House GARAGE!!
Villa Del Lago - Lakehouse on Lake Pepin
Living area
Villa Del Lago - Lakehouse on Lake Pepin
9.8 out of 10, Exceptional, (124)
"We loved the location. Walked down to the beach, watched so many eagles flying in and all the kids loved the trains. It’s a beautiful home and fit our big family. With that said, after spending over $1,000 for our weekend stay I had higher expectations. We found blood on a set of sheets/bedding. The shower drain was so clogged the tub filled halfway while showering and after spilling water on the floor we wiped it up and the paper towel was black. "
Villa Del Lago - Lakehouse on Lake Pepin
Park in the Garage and Walk to Mayo Clinic
King size bed with memory foam mattress in primary bedroom located upstairs.
Park in the Garage and Walk to Mayo Clinic
10.0 out of 10, Exceptional, (49)
"Staying here was so easy, and comfy! Traffic was simple to get to Mayo. And the owner was so very helpful and plesant! "
Park in the Garage and Walk to Mayo Clinic
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in Southern Minnesota

The Berkman
Lobby
The Berkman
3.0 star property
9.6 out of 10, Exceptional, (246)
"It was so nice to stay in an apartment rather than a hotel and everyone was so helpful. "
The price is AED 625
AED 726 total
includes taxes & fees
10 Oct - 11 Oct
The Berkman
Charming Cottage in Stockholm, WI Nations Best: Pies, Scenic Drive, Small Town!
Large Welcoming Shady Deck With Lake Breeze And Sunset Views
Charming Cottage in Stockholm, WI Nations Best: Pies, Scenic Drive, Small Town!
9.4 out of 10, Exceptional, (47)
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Charming Cottage in Stockholm, WI Nations Best: Pies, Scenic Drive, Small Town!
Broadway Plaza, Trademark Collection by Wyndham
Room
Broadway Plaza, Trademark Collection by Wyndham
3.0 star property
9.2 out of 10, Wonderful, (145)
"Great place to stay. Very handy for walking to the Mayo Clinic. Also very clean. Although we only stayed one night, it would be especially nice for longer stays as it really is a small apartment."
Broadway Plaza, Trademark Collection by Wyndham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.