Find hotels in South Central Houston, Houston from AED 220

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Discover 1,201 South Central Houston hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Zaza Houston Museum District

4.5 star property
9.0 out of 10, Wonderful, (1590)
"Excellent rooms great customer service "
The price is AED 988
AED 1,311 total
includes taxes & fees
2 Mar - 3 Mar
Hotel Zaza Houston Museum District

The Westin Houston Medical Center/Museum District

4.0 star property
9.0 out of 10, Wonderful, (1004)
"Amazing Great room"
The price is AED 590
AED 734 total
includes taxes & fees
22 Feb - 23 Feb
The Westin Houston Medical Center/Museum District

InterContinental Houston by IHG

4.0 star property
9.2 out of 10, Wonderful, (1004)
"The staff are always so nice and accommodating!"
The price is AED 694
AED 867 total
includes taxes & fees
22 Feb - 23 Feb
InterContinental Houston by IHG

Houston Stay

2.0 star property
10.0 out of 10, Exceptional, (3)
"This property is top tier! Location was perfect for the Toyota Center! The interstate was close by and the transit system was near as well! The home has all updated appliances and the floor plan is perfect for family travel. The host is very accommodating and quickly replies to any questions. Impeccably clean & spacious! 10 out of 10!!!! "
The price is AED 551
AED 1,483 total
includes taxes & fees
18 Feb - 19 Feb
Houston Stay

Hilton University of Houston

3.5 star property
8.8 out of 10, Excellent, (779)
"I enjoyed my stay it was very friendly and welcoming. "
The price is AED 584
AED 683 total
includes taxes & fees
23 Feb - 24 Feb
Hilton University of Houston

Hilton Houston Plaza/Medical Center

3.5 star property
8.4 out of 10, Very Good, (1205)
"The only problem was with parking validation. Although parking fee was paid for a 24hr period, I was only given a sticker instead of a parking tag. This caused an issue when leaving and returning for dinner."
The price is AED 352
AED 416 total
includes taxes & fees
23 Feb - 24 Feb
Hilton Houston Plaza/Medical Center

Houston Marriott Medical Center/Museum District

4.0 star property
9.0 out of 10, Wonderful, (1004)
"The staff was very nice and accommodating."
The price is AED 731
AED 862 total
includes taxes & fees
22 Feb - 23 Feb
Houston Marriott Medical Center/Museum District

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4.0 star property
8.4 out of 10, Very Good, (274)
"The hotel is very nice, not the best area. However, they charge $25 a day for parking. Our first week was through Expedia and no mention of parking. Second week we booked through the hotel and still no mention of parking. "
The price is AED 496
AED 581 total
includes taxes & fees
23 Feb - 24 Feb
DoubleTree by Hilton Houston Medical Center Hotel & Suites

Americas Best Value Inn Medical Center Downtown

2.0 star property
7.8 out of 10, Good, (1004)
"Conveniently located near med center. Clean and fully functional room. Breakfast offered was small but sufficient. Staff was friendly during check in/out. Lots of activity after dark made property feel relatively unsafe however. Noisy until midnight. Be aware of surroundings"
The price is AED 441
AED 516 total
includes taxes & fees
18 Feb - 19 Feb
Americas Best Value Inn Medical Center Downtown

La Maison in Midtown an urban B&B

3.5 star property
9.8 out of 10, Exceptional, (460)
"The whole place was very well maintained and very well done. Owners are super nice and responsive. Will stay there again if the situation arises."
The price is AED 585
AED 685 total
includes taxes & fees
23 Feb - 24 Feb
La Maison in Midtown an urban B&B

Posh Dtwn Midtown Home w Stunning Roof-topterrace

3.0 star property
The price is AED 1,680
AED 3,550 total
includes taxes & fees
5 Mar - 6 Mar
Posh Dtwn Midtown Home w Stunning Roof-topterrace

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

3.5 star property
9.6 out of 10, Exceptional, (181)
"Great"
The price is AED 687
AED 831 total
includes taxes & fees
12 Mar - 13 Mar
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

Scott Inn Suites - Downtown Houston

2.0 star property
8.6 out of 10, Excellent, (22)
"I appreciated the discounted rate at this location. In general it was clean and had the essentials. I did receive a towel that had a stain on it. But all in all a good stay!"
The price is AED 220
AED 258 total
includes taxes & fees
21 Feb - 22 Feb
Scott Inn Suites - Downtown Houston

Extended Stay America Suites Houston Med Ctr Braeswood Bl

2.5 star property
6.0 out of 10, (1007)
"Staff is very friendly "
The price is AED 314
AED 368 total
includes taxes & fees
26 Feb - 27 Feb
Extended Stay America Suites Houston Med Ctr Braeswood Bl

Paradise Palace Best Rooftop in HTX w Hot Tub

3.0 star property
The price is AED 1,298
AED 2,730 total
includes taxes & fees
5 Mar - 6 Mar
Paradise Palace Best Rooftop in HTX w Hot Tub

Luxury Downtown Getaway With Breathtaking Views

3.0 star property
10.0 out of 10, Exceptional, (3)
"We had a wonderful stay celebrating my birthday at this beautiful home. The comfy beds and great amenities like the pool table and rooftop lounge made it special. Issues encountered were resolved quickly. The checkout time felt tight given the cleaning tasks. Overall, we enjoyed our experience and would consider returning!"
The price is AED 876
AED 2,281 total
includes taxes & fees
23 Feb - 24 Feb
Luxury Downtown Getaway With Breathtaking Views

The Oasis Checkmate HTX Rooftop

3.0 star property
10.0 out of 10, Exceptional, (2)
"This place is amazing! Beautiful decor and location is perfect for any event near the convention center. Safe and secure. Hosts were responsive and friendly. I let them know the ironing board was missing and they had a new one sent from Amazon the next day! 10/10 recommend and will rebook. "
The price is AED 1,095
AED 2,661 total
includes taxes & fees
24 Feb - 25 Feb
The Oasis Checkmate HTX Rooftop

Rodeway Inn & Suites Houston near Medical Center

2.0 star property
6.2 out of 10, (436)
"Worked perfect for the night and kind people "
The price is AED 205
AED 251 total
includes taxes & fees
18 Feb - 19 Feb
Rodeway Inn & Suites Houston near Medical Center

Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home

3.0 star property
The price is AED 740
AED 2,097 total
includes taxes & fees
18 Feb - 19 Feb
Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home

Southmore Boulevard Motel

2.0 star property
5.4 out of 10, (209)
"Loved it"
The price is AED 281
AED 329 total
includes taxes & fees
2 Mar - 3 Mar
Southmore Boulevard Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in South Central Houston
Save an average of 15% on thousands of hotels when you're signed in

Frequently asked questions

What's it like in South Central Houston?

Travelers are sure to enjoy a stay in Houston's South Central Houston neighborhood. Looking for sights you might find in a travel guide about South Central Houston? Consider a visit to Houston Zoo while you're in the neighborhood.

What's the best accommodation in South Central Houston?

Based on Expedia customer reviews, La Maison in Midtown an urban B&B is a highly ranked property in South Central Houston. This B&B is a short 4-minute walk from Westheimer Rd, and it offers free breakfast and free parking. Other favorite options in the area include MyCrib Houston Hostel and Wanderstay Boutique Hotel.

How many hotels can I expect to find in the South Central Houston area?

Expedia has 1200 hotels and other accommodations in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.

If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?

Yes, the majority of hotel room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to review the best options available in South Central Houston.

Where can I learn more about changing or cancelling my trip to South Central Houston?

To access more information about changing or cancelling your trip to South Central Houston, go to https://www.expedia.com/service/.

What is there to do around this Houston neighborhood?

Spend some time exploring the great outdoors at Hermann Park, Cullen Sculpture Garden, and James Turrell's Twilight Epiphany Skyscape. Houston Zoo and Continental Club are some other stops to visit in the neighborhood. Toyota Center and Daikin Park are some favorite places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.

How can I get around South Central Houston and the greater Houston area?

For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station, or Ensemble/HCC Station.