Find Resorts & Hotels with Spas in Florence, SC

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check availability on Florence Resorts & Hotels with Spas

This weekend
Next weekend

Compare Florence Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Hampton Inn & Suites Florence Center

2.5 star property
9.2 out of 10, Wonderful, (718)
"I loved everything about this hotel"
The price is AED 465
AED 521 total
includes taxes & fees
13 Apr - 14 Apr
Hampton Inn & Suites Florence Center

Comfort Inn & Suites

2.5 star property
9.2 out of 10, Wonderful, (1192)
"Every thing was perfect "
The price is AED 372
AED 416 total
includes taxes & fees
27 Apr - 28 Apr
Comfort Inn & Suites

Homewood Suites by Hilton Florence

3.0 star property
8.4 out of 10, Very Good, (603)
"Loved the clean rooms and amenities. Hated the loud noise coming from the room above until 4am. "
The price is AED 465
AED 521 total
includes taxes & fees
13 Apr - 14 Apr
Homewood Suites by Hilton Florence

Comfort Suites Florence I-95

2.5 star property
8.6 out of 10, Excellent, (1072)
"Clean and spacious room "
The price is AED 375
AED 435 total
includes taxes & fees
27 Apr - 28 Apr
Comfort Suites Florence I-95

Country Inn & Suites by Radisson, Florence, SC

2.5 star property
7.6 out of 10, Good, (1077)
"The lady at the front desk with the blonde hair was great handled all my request with great customer service."
The price is AED 396
AED 452 total
includes taxes & fees
28 Apr - 29 Apr
Country Inn & Suites by Radisson, Florence, SC

TownePlace Suites by Marriott Florence

3.0 star property
9.0 out of 10, Wonderful, (567)
"Our room was clean and excellent. The staff were very friendly and helpful, it is very close and convenient to shopping centers, groceries, etc. The breakfast was amazing and there are laundry facilities.I will definitely stay here again!"
The price is AED 423
AED 474 total
includes taxes & fees
20 Apr - 21 Apr
TownePlace Suites by Marriott Florence

Howard Johnson by Wyndham Florence

2.0 star property
8.8 out of 10, Excellent, (2407)
"Very nice place, clean, affordable, great location, great employees, etc"
The price is AED 258
AED 289 total
includes taxes & fees
2 Apr - 3 Apr
Howard Johnson by Wyndham Florence

Park Inn by Radisson Florence, SC

2.5 star property
9.0 out of 10, Wonderful, (2216)
"Everything was great! Everyone was very nice and professional. The room was very clean and comfortable. "
The price is AED 386
AED 432 total
includes taxes & fees
13 Apr - 14 Apr
Park Inn by Radisson Florence, SC

Staybridge Suites Florence - Civic Center by IHG

3.0 star property
9.4 out of 10, Exceptional, (824)
"Clean room and quiet, right off of 95 and super close to gas stations, Target and many other shops and restaurants. Traveling to Florida from the northeast with my dog and I usually stop in this area. Plenty of grassy area to walk my dog to relieve herself. Everyone is very friendly here! Appreciate the full sized fridge and cookware, as I always pack a cooler so I don’t have to rely on area restaurants."
The price is AED 544
AED 609 total
includes taxes & fees
20 Apr - 21 Apr
Staybridge Suites Florence - Civic Center by IHG

Tru by Hilton Florence I-95

2.5 star property
8.4 out of 10, Very Good, (1099)
"Place was clean, the staff were nice. Room was small with few amenities. No microwave in the room. Breakfast was decent."
The price is AED 397
AED 457 total
includes taxes & fees
27 Apr - 28 Apr
Tru by Hilton Florence I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Florence

Frequently asked questions

Looking to vacation at a spa hotel in Florence?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers highly recommend the restaurants in Florence. Be sure to pay a visit to the museums during your stay. Spa hotels are a great way to break out of your routine and add a layer of luxury to your holiday.
What is the best spa hotel in Florence?
Hotel Florence, Tapestry Collection by Hilton is a top spa hotel featuring a 24-hour fitness center, a bar, and a restaurant. Enjoy a facial, detox wrap, or Swedish massage at the onsite spa.
How many spa hotels are there in Florence?
Among Expedia’s 94 accommodation options in Florence, there is 1 spa hotel.
What's there to see and do in Florence?
Enjoy all that Florence has to offer when you visit Florence Museum, Florence National Cemetery, and Magnolia Mall. If you have extra time while you’re in the area, you might want to see Florence Civic Center and Palmetto Shores Lake.
What is a Florence spa hotel?
Spa hotels in Florence provide lodging and have an on-site spa which offers services like couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.