Find Resorts & Hotels with Spas in Florence, SC

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check availability on Florence Resorts & Hotels with Spas

Next weekend
In two weeks

Compare Florence Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Hampton Inn & Suites Florence Center

2.5 star property
9.2 out of 10, Wonderful, (743)
"Hotel staff was incredibly friendly and helpful."
The price is AED 476
AED 533 total
includes taxes & fees
2 Jun - 3 Jun
Hampton Inn & Suites Florence Center

Comfort Inn & Suites

2.5 star property
9.2 out of 10, Wonderful, (995)
"Great hotel"
The price is AED 382
AED 428 total
includes taxes & fees
18 May - 19 May
Comfort Inn & Suites

Homewood Suites by Hilton Florence

3.0 star property
8.4 out of 10, Very Good, (607)
"Happy staff, excellent environment I’ll always stay there when I’m in town"
The price is AED 465
AED 521 total
includes taxes & fees
11 May - 12 May
Homewood Suites by Hilton Florence

Comfort Suites Florence I-95

2.5 star property
8.6 out of 10, Excellent, (996)
"These rooms are amazing"
The price is AED 377
AED 437 total
includes taxes & fees
18 May - 19 May
Comfort Suites Florence I-95

Country Inn & Suites by Radisson, Florence, SC

2.5 star property
7.6 out of 10, Good, (1002)
"Not The same as pictures show ! False advertising, front desk clerk was nice but that’s about it . This is a terrible hotel "
The price is AED 407
AED 465 total
includes taxes & fees
25 May - 26 May
Country Inn & Suites by Radisson, Florence, SC

TownePlace Suites by Marriott Florence

3.0 star property
9.0 out of 10, Wonderful, (579)
"Clean, staff was friendly! "
The price is AED 423
AED 474 total
includes taxes & fees
1 Jun - 2 Jun
TownePlace Suites by Marriott Florence

Howard Johnson by Wyndham Florence

2.0 star property
8.8 out of 10, Excellent, (2198)
"A very good price-quality for a short stay, and may restaurants around"
The price is AED 241
AED 270 total
includes taxes & fees
5 May - 6 May
Howard Johnson by Wyndham Florence

Park Inn by Radisson Florence, SC

2.5 star property
9.0 out of 10, Wonderful, (2051)
"Nice rooms , good price , great breakfast "
The price is AED 364
AED 407 total
includes taxes & fees
18 May - 19 May
Park Inn by Radisson Florence, SC

Staybridge Suites Florence - Civic Center by IHG

3.0 star property
9.4 out of 10, Exceptional, (838)
"The hotel is set back in an area of other hotels and is quiet. We stayed in a one bedroom unit that was well designed with a kitchen that had everything we needed and a comfortable living area. There are plenty of restaurants nearby and the hotel offers a great breakfast."
The price is AED 525
AED 588 total
includes taxes & fees
1 Jun - 2 Jun
Staybridge Suites Florence - Civic Center by IHG

Tru by Hilton Florence I-95

2.5 star property
8.2 out of 10, Very Good, (1000)
"Very nice location , staff very pleasent."
The price is AED 372
AED 429 total
includes taxes & fees
18 May - 19 May
Tru by Hilton Florence I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Florence

Frequently asked questions

Looking to vacation at a spa hotel in Florence?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers highly recommend the restaurants in Florence. Be sure to pay a visit to the museums during your stay. Spa hotels are a great way to break out of your routine and add a layer of luxury to your holiday.
What is the best spa hotel in Florence?
Hotel Florence, Tapestry Collection by Hilton is a top spa hotel featuring a 24-hour fitness center, a bar, and a restaurant. Enjoy a facial, detox wrap, or Swedish massage at the onsite spa.
How many spa hotels are there in Florence?
Among Expedia’s 95 accommodation options in Florence, there is 1 spa hotel.
What's there to see and do in Florence?
Enjoy all that Florence has to offer when you visit Florence Museum, Florence National Cemetery, and Magnolia Mall. If you have extra time while you’re in the area, you might want to see Florence Civic Center and Palmetto Shores Lake.
What is a Florence spa hotel?
Spa hotels in Florence provide lodging and have an on-site spa which offers services like couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.