Find Resorts & Hotels with Spas in Florence, SC

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Check availability on Florence Resorts & Hotels with Spas

Compare Florence Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Hampton Inn & Suites Florence Center

2.5 star property
9.2 out of 10, Wonderful, (734)
"Hotel was very convenient off 95. Room was clean and spacious. Free breakfast was nice. Many restaurant options for dinner."
The price is AED 465
AED 521 total
includes taxes & fees
20 Apr - 21 Apr
Hampton Inn & Suites Florence Center

Comfort Inn & Suites

2.5 star property
9.2 out of 10, Wonderful, (998)
"Great hotel"
The price is AED 374
AED 419 total
includes taxes & fees
4 May - 5 May
Comfort Inn & Suites

Homewood Suites by Hilton Florence

3.0 star property
8.4 out of 10, Very Good, (606)
"We stay in this Homewood Suites once or twice a year. It is clean with comfortable beds and a nice staff. Having a full refrigerator is important to us. It's location right off I95 is very convenient. "
The price is AED 465
AED 521 total
includes taxes & fees
20 Apr - 21 Apr
Homewood Suites by Hilton Florence

Comfort Suites Florence I-95

2.5 star property
8.6 out of 10, Excellent, (999)
"Great experience friendly staff "
The price is AED 377
AED 437 total
includes taxes & fees
4 May - 5 May
Comfort Suites Florence I-95

Country Inn & Suites by Radisson, Florence, SC

2.5 star property
7.6 out of 10, Good, (1004)
"I was charged twice for my room on my card, once by Hotels.com and again by the hotel. So desk service not so good! Ok to Good on the rest of the stay."
The price is AED 397
AED 454 total
includes taxes & fees
5 May - 6 May
Country Inn & Suites by Radisson, Florence, SC

TownePlace Suites by Marriott Florence

3.0 star property
9.0 out of 10, Wonderful, (571)
"Our room was clean and excellent. The staff were very friendly and helpful, it is very close and convenient to shopping centers, groceries, etc. The breakfast was amazing and there are laundry facilities.I will definitely stay here again!"
The price is AED 423
AED 474 total
includes taxes & fees
4 May - 5 May
TownePlace Suites by Marriott Florence

Howard Johnson by Wyndham Florence

2.0 star property
8.8 out of 10, Excellent, (2189)
"We had a overnight stay, good room, good breakfast "
The price is AED 241
AED 270 total
includes taxes & fees
14 Apr - 15 Apr
Howard Johnson by Wyndham Florence

Park Inn by Radisson Florence, SC

2.5 star property
9.0 out of 10, Wonderful, (2020)
"X"
The price is AED 364
AED 407 total
includes taxes & fees
4 May - 5 May
Park Inn by Radisson Florence, SC

Staybridge Suites Florence - Civic Center by IHG

3.0 star property
9.4 out of 10, Exceptional, (832)
"Clean room and quiet, right off of 95 and super close to gas stations, Target and many other shops and restaurants. Traveling to Florida from the northeast with my dog and I usually stop in this area. Plenty of grassy area to walk my dog to relieve herself. Everyone is very friendly here! Appreciate the full sized fridge and cookware, as I always pack a cooler so I don’t have to rely on area restaurants."
The price is AED 529
AED 592 total
includes taxes & fees
20 Apr - 21 Apr
Staybridge Suites Florence - Civic Center by IHG

Tru by Hilton Florence I-95

2.5 star property
8.2 out of 10, Very Good, (1003)
"Amazing stay! The kids had a blast in the pool and enjoyed the fun pancakes. Staff was super kind and welcoming! "
The price is AED 372
AED 429 total
includes taxes & fees
4 May - 5 May
Tru by Hilton Florence I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking to vacation at a spa hotel in Florence?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers highly recommend the restaurants in Florence. Be sure to pay a visit to the museums during your stay. Spa hotels are a great way to break out of your routine and add a layer of luxury to your holiday.
What is the best spa hotel in Florence?
Hotel Florence, Tapestry Collection by Hilton is a top spa hotel featuring a 24-hour fitness center, a bar, and a restaurant. Enjoy a facial, detox wrap, or Swedish massage at the onsite spa.
How many spa hotels are there in Florence?
Among Expedia’s 94 accommodation options in Florence, there is 1 spa hotel.
What's there to see and do in Florence?
Enjoy all that Florence has to offer when you visit Florence Museum, Florence National Cemetery, and Magnolia Mall. If you have extra time while you’re in the area, you might want to see Florence Civic Center and Palmetto Shores Lake.
What is a Florence spa hotel?
Spa hotels in Florence provide lodging and have an on-site spa which offers services like couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.