Find Luxury Hotels in Florence, SC

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Check availability on Florence Luxury Hotels

Compare Florence Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

The Mantissa Hotel
Exterior

The Mantissa Hotel

3.0 star property
9.2 out of 10, Wonderful, (223)
"Great looking room and nice amenities."
The price is AED 625
AED 700 total
includes taxes & fees
23 Mar - 24 Mar
The Mantissa Hotel
Days Inn by Wyndham Dillon
Business center

Days Inn by Wyndham Dillon

2.0 star property
5.4 out of 10, (751)
"Staff friendly, older property, good breakfast "
The price is AED 247
AED 276 total
includes taxes & fees
13 Mar - 14 Mar
Days Inn by Wyndham Dillon
Hotel Florence, Tapestry Collection by Hilton
Exterior

Hotel Florence, Tapestry Collection by Hilton

3.0 star property
8.8 out of 10, Excellent, (556)
"Always a nice clean and comfortable stay!! Doesn’t feel like your traditional hotels!! "
The price is AED 559
AED 626 total
includes taxes & fees
23 Mar - 24 Mar
Hotel Florence, Tapestry Collection by Hilton
Days Inn by Wyndham Florence/I-95 North
Lobby

Days Inn by Wyndham Florence/I-95 North

2.0 star property
6.8 out of 10, (1007)
"The room was very comfortable. The shower was hot. The inside was renovated and clean. Breakfast was good. Fresh fruit would have been nice. The staff was friendly and helpful."
The price is AED 235
AED 263 total
includes taxes & fees
13 Mar - 14 Mar
Days Inn by Wyndham Florence/I-95 North
Baymont Inn & Suites Florence by Wyndham
Exterior

Baymont Inn & Suites Florence by Wyndham

2.5 star property
5.6 out of 10, (1002)
"Still in Renovation mode "
Baymont Inn & Suites Florence by Wyndham
Clarion Inn & Suites
Lobby

Clarion Inn & Suites

2.5 star property
4.4 out of 10, (266)
"Won't say nothing too bad but it was a different experience "
Clarion Inn & Suites
Red Roof Inn Florence - Civic Center
Desk, laptop workspace, free cribs/infant beds, free WiFi

Red Roof Inn Florence - Civic Center

2.0 star property
6.8 out of 10, (1010)
"For the price and location I would recommend this motel. They give you the essentials for a comfortable stay. I would stay again if in Florence "
The price is AED 206
AED 231 total
includes taxes & fees
16 Mar - 17 Mar
Red Roof Inn Florence - Civic Center
Days Inn by Wyndham Florence Near Civic Center
Seasonal outdoor pool

Days Inn by Wyndham Florence Near Civic Center

2.5 star property
6.6 out of 10, (1016)
"Great check-in and the desk clerks were all awesome. "
The price is AED 218
AED 244 total
includes taxes & fees
12 Mar - 13 Mar
Days Inn by Wyndham Florence Near Civic Center
Quality Inn & Suites
Standard Room, 1 King Bed with Sofa bed, Non Smoking | Desk, iron/ironing board, rollaway beds, free WiFi

Quality Inn & Suites

2.5 star property
7.4 out of 10, Good, (649)
"Location. Nice breakfast "
The price is AED 353
AED 395 total
includes taxes & fees
11 Mar - 12 Mar
Quality Inn & Suites
Quality Inn & Suites Florence Civic Center
Exterior

Quality Inn & Suites Florence Civic Center

2.5 star property
8.0 out of 10, Very Good, (1131)
"Good service "
The price is AED 327
AED 366 total
includes taxes & fees
16 Mar - 17 Mar
Quality Inn & Suites Florence Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are you searching for the perfect hotel for your luxury holiday in Florence?
Expedia can help you get a flight to Florence, SC (FLO-Florence Regional) airport, and then you can select from a variety of places to stay that will deliver the luxury you seek. Amenities are an important consideration when you plan a vacation, so we make it easy to find what you’d like to make your stay special. If you want a posh hotel that has a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Florence offers. During your visit, you might want to enjoy the shopping which Florence is known for.
How many luxury hotels will I be able to find in Florence?
Lie in the lap of luxury during your getaway to Florence in one of Expedia’s 20 luxury hotels.
When can I expect good weather in Florence?
Planning for the weather is a good way to make your trip to Florence relaxing and enjoyable, especially when you’re splurging. The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 50°F. Average annual precipitation for Florence is 54 inches.
What's there to see and do in Florence?
Take in the sights and attractions that Florence offers with a visit to Florence Museum, Florence National Cemetery, and Magnolia Mall. If you have extra time while you’re in the area, you might want to stop by Florence Civic Center and Palmetto Shores Lake.
How can I get around Florence?
It’s easier to get around town in style when you know your options. If you want to venture outside of the area, hop aboard a train at Florence Station.