Find Luxury Hotels in Florence, SC

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Check availability on Florence Luxury Hotels

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Compare Florence Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

The Mantissa Hotel

3.0 star property
9.2 out of 10, Wonderful, (218)
"The property was clean but price not worth Hartsville"
The price is AED 625
AED 700 total
includes taxes & fees
15 Feb - 16 Feb
The Mantissa Hotel

Days Inn by Wyndham Dillon

2.0 star property
5.4 out of 10, (734)
"Everything was OK"
The price is AED 231
AED 259 total
includes taxes & fees
4 Feb - 5 Feb
Days Inn by Wyndham Dillon

Hotel Florence, Tapestry Collection by Hilton

3.0 star property
8.8 out of 10, Excellent, (548)
"Check in person not pleasant. Did not smile or was welcoming in any way or offer any suggestions for dining. Did not show us where elevator was located when there’s no sign. Disinterested attitude. "
The price is AED 487
AED 545 total
includes taxes & fees
9 Feb - 10 Feb
Hotel Florence, Tapestry Collection by Hilton

Days Inn by Wyndham Florence/I-95 North

2.0 star property
7.0 out of 10, Good, (1009)
"Easy to get to highway "
The price is AED 219
AED 245 total
includes taxes & fees
16 Feb - 17 Feb
Days Inn by Wyndham Florence/I-95 North

Baymont Inn & Suites Florence by Wyndham

2.5 star property
5.6 out of 10, (1000)
"Still in Renovation mode "
Baymont Inn & Suites Florence by Wyndham

Clarion Inn & Suites

2.5 star property
4.4 out of 10, (262)
"Disgusting, unsafe, bugs, holes in the walls, smoke detector broken"
The price is AED 182
AED 204 total
includes taxes & fees
4 Feb - 5 Feb
Clarion Inn & Suites

Red Roof Inn Florence - Civic Center

2.0 star property
6.8 out of 10, (1004)
"Needs some help"
The price is AED 193
AED 216 total
includes taxes & fees
16 Feb - 17 Feb
Red Roof Inn Florence - Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 star property
6.6 out of 10, (1009)
"I had a king size bed and it almost turned me over. It wasn't anchored properly or something... Bathroom was fairly clean"
The price is AED 209
AED 234 total
includes taxes & fees
9 Feb - 10 Feb
Days Inn by Wyndham Florence Near Civic Center

Quality Inn & Suites

2.5 star property
7.4 out of 10, Good, (635)
"Gpood"
The price is AED 322
AED 361 total
includes taxes & fees
16 Feb - 17 Feb
Quality Inn & Suites

Quality Inn & Suites Florence Civic Center

2.5 star property
8.0 out of 10, Very Good, (1087)
"Friendly staff, clean and comfortable room. Multiple restaurants within walking distance. I would stay here again. "
The price is AED 330
AED 370 total
includes taxes & fees
2 Mar - 3 Mar
Quality Inn & Suites Florence Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are you searching for the perfect hotel for your luxury holiday in Florence?
Expedia can help you get a flight to Florence, SC (FLO-Florence Regional) airport, and then you can select from a variety of places to stay that will deliver the luxury you seek. Amenities are an important consideration when you plan a vacation, so we make it easy to find what you’d like to make your stay special. If you want a posh hotel that has a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Florence offers. During your visit, you might want to enjoy the shopping which Florence is known for.
How many luxury hotels will I be able to find in Florence?
Lie in the lap of luxury during your getaway to Florence in one of Expedia’s 20 luxury hotels.
When can I expect good weather in Florence?
Planning for the weather is a good way to make your trip to Florence relaxing and enjoyable, especially when you’re splurging. The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 50°F. Average annual precipitation for Florence is 54 inches.
What's there to see and do in Florence?
Take in the sights and attractions that Florence offers with a visit to Florence Museum, Florence National Cemetery, and Magnolia Mall. If you have extra time while you’re in the area, you might want to stop by Florence Civic Center and Palmetto Shores Lake.
How can I get around Florence?
It’s easier to get around town in style when you know your options. If you want to venture outside of the area, hop aboard a train at Florence Station.