Find Luxury Hotels in Florence, SC

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Compare Florence Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

The Mantissa Hotel
Exterior

The Mantissa Hotel

3.0 star property
9.2 out of 10, Wonderful, (214)
"Great rooms."
The price is AED 625
AED 700 total
includes taxes & fees
5 Jan - 6 January 2025
The Mantissa Hotel
Days Inn by Wyndham Dillon
Business center

Days Inn by Wyndham Dillon

2.0 star property
5.4 out of 10, (695)
" Inexpensive easy to get to. Friendly helpful staff."
The price is AED 231
AED 259 total
includes taxes & fees
25 Dec - 26 Dec
Days Inn by Wyndham Dillon
Hotel Florence, Tapestry Collection by Hilton
Exterior

Hotel Florence, Tapestry Collection by Hilton

3.0 star property
8.8 out of 10, Excellent, (539)
"Very nice boutique hotel with spa gym and a very good restaurant on the main level. Very charming setting in a very walkable downtown. neighborhood clise to shops and restaurants."
The price is AED 465
AED 521 total
includes taxes & fees
12 Jan - 13 January 2025
Hotel Florence, Tapestry Collection by Hilton
Days Inn by Wyndham Florence/I-95 North
Lobby

Days Inn by Wyndham Florence/I-95 North

2.0 star property
7.0 out of 10, Good, (1008)
"Very helpful staff getting me a great room. Very clean and comfortable. This is just a night on a through trip but it is perfect"
The price is AED 221
AED 248 total
includes taxes & fees
29 Dec - 30 Dec
Days Inn by Wyndham Florence/I-95 North
Baymont Inn & Suites Florence by Wyndham
Exterior

Baymont Inn & Suites Florence by Wyndham

2.5 star property
5.6 out of 10, (1000)
"Still in Renovation mode "
Baymont Inn & Suites Florence by Wyndham
Clarion Inn & Suites
Exterior

Clarion Inn & Suites

2.5 star property
4.6 out of 10, (253)
"The staff went above and beyond to provide exceptional service and the room was extremely clean."
The price is AED 182
AED 204 total
includes taxes & fees
25 Dec - 26 Dec
Clarion Inn & Suites
Red Roof Inn Florence - Civic Center
Exterior

Red Roof Inn Florence - Civic Center

2.0 star property
6.8 out of 10, (1003)
"Great location. Room left a lot to be done. Not very clean, old and crumbling. Microwave that didn’t work. "
The price is AED 223
AED 250 total
includes taxes & fees
29 Dec - 30 Dec
Red Roof Inn Florence - Civic Center
Days Inn by Wyndham Florence Near Civic Center
Pool

Days Inn by Wyndham Florence Near Civic Center

2.5 star property
6.6 out of 10, (1006)
"Check in was quick"
The price is AED 209
AED 234 total
includes taxes & fees
29 Dec - 30 Dec
Days Inn by Wyndham Florence Near Civic Center
Quality Inn & Suites
Exterior

Quality Inn & Suites

2.5 star property
7.4 out of 10, Good, (617)
"The staff was friendly and efficient and helpful and the one night stay was quiet and restful. "
The price is AED 331
AED 370 total
includes taxes & fees
23 Dec - 24 Dec
Quality Inn & Suites
Quality Inn & Suites Florence Civic Center
Exterior

Quality Inn & Suites Florence Civic Center

2.5 star property
7.8 out of 10, Good, (1019)
"Clean and excellent service"
The price is AED 319
AED 357 total
includes taxes & fees
19 Jan - 20 January 2025
Quality Inn & Suites Florence Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are you searching for the perfect hotel for your luxury holiday in Florence?
Expedia can help you get a flight to Florence, SC (FLO-Florence Regional) airport, and then you can select from a variety of places to stay that will deliver the luxury you seek. Amenities are an important consideration when you plan a vacation, so we make it easy to find what you’d like to make your stay special. If you want a posh hotel that has a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Florence offers. During your visit, you might want to enjoy the shopping which Florence is known for.
How many luxury hotels will I be able to find in Florence?
Lie in the lap of luxury during your getaway to Florence in one of Expedia’s 20 luxury hotels.
When can I expect good weather in Florence?
Planning for the weather is a good way to make your trip to Florence relaxing and enjoyable, especially when you’re splurging. The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 50°F. Average annual precipitation for Florence is 54 inches.
What's there to see and do in Florence?
Take in the sights and attractions that Florence offers with a visit to Florence Museum, Florence National Cemetery, and Magnolia Mall. If you have extra time while you’re in the area, you might want to stop by Florence Civic Center and Palmetto Shores Lake.
How can I get around Florence?
It’s easier to get around town in style when you know your options. If you want to venture outside of the area, hop aboard a train at Florence Station.