Find Luxury Hotels in Florence, SC

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Check availability on Florence Luxury Hotels

Compare Florence Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

The Mantissa Hotel
Rooftop terrace

The Mantissa Hotel

3.0 star property
9.2 out of 10, Wonderful, (231)
"This property is a gem! I would recommend this hotel to anyone that would fins themselves in the Hartsville/Darlington area!"
The price is AED 625
AED 700 total
includes taxes & fees
26 Apr - 27 Apr
The Mantissa Hotel
Days Inn by Wyndham Dillon
Exterior

Days Inn by Wyndham Dillon

2.0 star property
5.4 out of 10, (765)
"Staff friendly, older property, good breakfast "
The price is AED 247
AED 276 total
includes taxes & fees
23 Apr - 24 Apr
Days Inn by Wyndham Dillon
Hotel Florence, Tapestry Collection by Hilton
Exterior

Hotel Florence, Tapestry Collection by Hilton

3.0 star property
8.8 out of 10, Excellent, (561)
"Awesome "
The price is AED 481
AED 538 total
includes taxes & fees
20 Apr - 21 Apr
Hotel Florence, Tapestry Collection by Hilton
Days Inn by Wyndham Florence/I-95 North
Lobby

Days Inn by Wyndham Florence/I-95 North

2.0 star property
6.8 out of 10, (1009)
"The floors were dirty."
The price is AED 212
AED 238 total
includes taxes & fees
27 Apr - 28 Apr
Days Inn by Wyndham Florence/I-95 North
Baymont Inn & Suites Florence by Wyndham
Exterior

Baymont Inn & Suites Florence by Wyndham

2.5 star property
5.6 out of 10, (1000)
"Still in Renovation mode "
Baymont Inn & Suites Florence by Wyndham
Clarion Inn & Suites
Exterior

Clarion Inn & Suites

2.5 star property
4.4 out of 10, (266)
"Won't say nothing too bad but it was a different experience "
Clarion Inn & Suites
Red Roof Inn Florence - Civic Center
Desk, laptop workspace, free cribs/infant beds, free WiFi

Red Roof Inn Florence - Civic Center

2.0 star property
6.8 out of 10, (1007)
"Clean rooms "
The price is AED 206
AED 231 total
includes taxes & fees
16 Apr - 17 Apr
Red Roof Inn Florence - Civic Center
Days Inn by Wyndham Florence Near Civic Center
Desk, iron/ironing board, free WiFi, bed sheets

Days Inn by Wyndham Florence Near Civic Center

2.5 star property
6.6 out of 10, (1008)
"Property was well kept and clean. Area was convenient to shopping and dining. Price was a bit higher due to events in the area but otherwise a good stay. "
The price is AED 234
AED 262 total
includes taxes & fees
15 Apr - 16 Apr
Days Inn by Wyndham Florence Near Civic Center
Quality Inn & Suites
Standard Room, 1 King Bed with Sofa bed, Non Smoking | Desk, iron/ironing board, rollaway beds, free WiFi

Quality Inn & Suites

2.5 star property
7.4 out of 10, Good, (656)
"Rooms where clean and just a little noisy from traffic"
The price is AED 318
AED 356 total
includes taxes & fees
27 Apr - 28 Apr
Quality Inn & Suites
Quality Inn & Suites Florence Civic Center
Premium bedding, in-room safe, desk, iron/ironing board

Quality Inn & Suites Florence Civic Center

2.5 star property
7.8 out of 10, Good, (1178)
"These properties have struggled to stay in business. Staffers are underpaid and increasingly indifferent. Families can’t feel relaxed "
The price is AED 331
AED 370 total
includes taxes & fees
20 Apr - 21 Apr
Quality Inn & Suites Florence Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are you searching for the perfect hotel for your luxury holiday in Florence?
Expedia can help you get a flight to Florence, SC (FLO-Florence Regional) airport, and then you can select from a variety of places to stay that will deliver the luxury you seek. Amenities are an important consideration when you plan a vacation, so we make it easy to find what you’d like to make your stay special. If you want a posh hotel that has a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Florence offers. During your visit, you might want to enjoy the shopping which Florence is known for.
How many luxury hotels will I be able to find in Florence?
Lie in the lap of luxury during your getaway to Florence in one of Expedia’s 20 luxury hotels.
When can I expect good weather in Florence?
Planning for the weather is a good way to make your trip to Florence relaxing and enjoyable, especially when you’re splurging. The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 50°F. Average annual precipitation for Florence is 54 inches.
What's there to see and do in Florence?
Take in the sights and attractions that Florence offers with a visit to Florence Museum, Florence National Cemetery, and Magnolia Mall. If you have extra time while you’re in the area, you might want to stop by Florence Civic Center and Palmetto Shores Lake.
How can I get around Florence?
It’s easier to get around town in style when you know your options. If you want to venture outside of the area, hop aboard a train at Florence Station.