Find 4 Star Hotels in Florence, SC

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check availability on Florence 4 Star Hotels

Tonight
1 May - 2 May
Tomorrow
2 May - 3 May
This weekend
2 May - 4 May
Next weekend
9 May - 11 May

Compare Florence 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Rosewood Manor House B&B
Exterior

Rosewood Manor House B&B

4.0 star property
10.0 out of 10, Exceptional, (29)
"the owners were incredibly gracious in turning our exhausting day into a pleasurable experience. The breakfast was delicious and the room was very comfortable."
Rosewood Manor House B&B
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Florence and related destinations

Explore the historic buildings and museums of this delightful South Carolina city that’s also known for its nature trails and outdoor pursuits.

See all hotels in Florence

Find great shopping malls, excellent dining and lush surrounding woodland in these two charming townships on the border of New York and New Jersey.

See all hotels in Mahwah - Nanuet
Mahwah - Nanuet featuring signage and a bar
Photo by NC Tourism - Bill Russ
Open Photo by NC Tourism - Bill Russ

Katy awaits: its cafes, opera, entertainment, and more!

See all hotels in Katy

Straddle the state line between Texas and Arkansas and take photos of the town’s famous courthouse and a painting paying homage to an influential musician.

See all hotels in Texarkana
Texarkana
Photo by Photo Courtesy Arkansas Department of Parks and Tourism
Open Photo by Photo Courtesy Arkansas Department of Parks and Tourism

Rolla awaits: its food, museums, opera, and more!

See all hotels in Rolla
Floating
Photo by Fauncefus
Open Photo by Fauncefus