Find hotels in East Main Street, Grand Junction from AED 172
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Discover 570 East Main Street hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

The Homestead
The Homestead
10.0 out of 10, Exceptional, (34)
The price is AED 745
AED 784 total
includes taxes & fees
14 Apr - 15 Apr

Spoke and Vine Motel
Spoke and Vine Motel
9.8 out of 10, Exceptional, (147)
The price is AED 585
AED 649 total
includes taxes & fees
6 May - 7 May

Wine Country Inn Palisade
Wine Country Inn Palisade
9.6 out of 10, Exceptional, (1005)
The price is AED 621
AED 688 total
includes taxes & fees
14 Apr - 15 Apr

Best Western Grande River Inn & Suites
Best Western Grande River Inn & Suites
9.0 out of 10, Wonderful, (674)
The price is AED 403
AED 424 total
includes taxes & fees
20 Apr - 21 Apr

Motel 6 Grand Junction, CO
Motel 6 Grand Junction, CO
6.2 out of 10, (1000)
The price is AED 187
AED 215 total
includes taxes & fees
18 Apr - 19 Apr

Residence Inn by Marriott Grand Junction
Residence Inn by Marriott Grand Junction
8.8 out of 10, Excellent, (444)
The price is AED 386
AED 442 total
includes taxes & fees
17 Apr - 18 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in East Main Street
Where to stay in East Main Street
Hotels in top Grand Junction neighborhoods Learn more about East Main Street

Redlands
1 out of top 10 points of interest in this area
You'll enjoy the mountain views and wineries in Redlands. You might want to make time for a stop at Colorado National Monument or Redlands Mesa Golf Club.
Recent reviews of East Main Street hotels
Recent reviews of East Main Street hotels

La Quinta Inn & Suites by Wyndham Grand Junction
5/5 Excellent
Excellent quality for price.
"Nice, clean room. Good breakfast. Also received shuttle service back to the airport on request."
A verified traveler stayed at La Quinta Inn & Suites by Wyndham Grand Junction
Posted 18 hours ago
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Hotels near popular Grand Junction Attractions
- Hotels near Colorado River
- Hotels near Colorado Mesa University
- Hotels near Colorado National Monument
- Hotels near Canyon View Park
- Hotels near Redlands Mesa Golf Club
- Hotels near Two Rivers Convention Center
- Hotels near Bananas Fun Park
- Hotels near Mesa County Fairgrounds
- Hotels near Grand Junction Motor Speedway
- Hotels near Gunnison River
More Accommodation Types in East Main Street
Hotels Close to Nearby Airports
East Main Street Hotels by Star Rating
East Main Street Hotels by Brand
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- Tru by Hilton Grand Junction Downtown
- Camp Eddy
- Home2 Suites by Hilton Grand Junction Northwest
- Studio 6 Grand Junction, CO
- Super 8 by Wyndham Fruita
- Hampton Inn Grand Junction Downtown/Historic Main Street