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Check Cayo Guillermo hotel prices

Tonight
21 Nov - 22 Nov
Tomorrow night
22 Nov - 23 Nov
This weekend
22 Nov - 24 Nov
Next weekend
29 Nov - 1 Dec

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Compare 7 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

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Frequently asked questions

Where can I learn more about changing or cancelling my trip to Cayo Guillermo?

For more information about rescheduling or cancelling your trip to Cayo Guillermo, head over to our customer service page.

What's the weather like in Cayo Guillermo?

The hottest months are usually August and September with an average temp of 83°F, while the coldest months are January and March with an average of 76°F. Average annual precipitation for Cayo Guillermo is 45 inches.