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Check availability on Cayo Guillermo 4 Star Hotels

Compare Cayo Guillermo 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Iberostar Daiquirí - All inclusive

4.0 star property
6.6 out of 10, (41)
"The location of the hotel, staff, food and entertainment are great. We felt it’s a well designed hotel (Believe just over 300 rooms) as it never felt overcrowded nor overlooked. The staff are wonderfully helpful and friendly and plenty around. "
Iberostar Daiquirí - All inclusive
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Learn more about Cayo Guillermo

Come to Cayo Guillermo and enjoy its wildlife, entertainment, and beaches.

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Cayo Guillermo?
We can help you quickly locate the ideal 4-star hotel for your vacation in Cayo Guillermo. Use our handy filter tool to fine-tune your search by things like price, conveniences and property star rating and get access to awesome deals in a few clicks.

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What's the difference between 5-star and 4-star hotels in Cayo Guillermo?
If you choose to spend your vacation at a 4-star hotel in Cayo Guillermo, you’ll usually find lots of conveniences to keep you comfortable, such as a restaurant, pool and gym. You can experience top-quality service and upscale accommodations. Go for a 5-star hotel and you’ll get a few more bells and whistles — think on-site spas, concierge assistance and indulgent turndown services. You’ll most likely get more amenities and exclusive services at a 5-star getaway, but both are awesome options for luxury travelers.
Does Cayo Guillermo have any 4-star all-inclusive resorts?
Enjoy a stress-free vacation experience where just about everything is included in one upfront price by using our “All inclusive” filter. Budgeting is a breeze when your room, food, activities and entertainment are already taken care of. After something a little different? Check out the great deals on our standard 4-star options in and around Cayo Guillermo too.