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Check availability on Cayo Guillermo 4 Star Hotels

Compare Cayo Guillermo 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Grand Muthu Cayo Guillermo
Outdoor pool

Hotel Grand Muthu Cayo Guillermo

3.5 star property
Hotel Grand Muthu Cayo Guillermo
Club Cayo Guillermo - All Inclusive
View from room

Club Cayo Guillermo - All Inclusive

3.5 star property
6.0 out of 10, (1)
"В целом неплохо. Отель вроде хороший но номера грязные и убитые. Кормят нормально. На пляже водоросли "
Club Cayo Guillermo - All Inclusive
Iberostar Daiquirí - All inclusive
2 outdoor pools, pool umbrellas

Iberostar Daiquirí - All inclusive

4.0 star property
6.6 out of 10, (41)
"The location of the hotel, staff, food and entertainment are great. We felt it’s a well designed hotel (Believe just over 300 rooms) as it never felt overcrowded nor overlooked. The staff are wonderfully helpful and friendly and plenty around. "
Iberostar Daiquirí - All inclusive
Villa Gregorio
On the beach

Villa Gregorio

2.5 star property
7.6 out of 10, Good, (9)
"Zimmer ohne Fenster, schlechte ölige Pommes, unfreundliches Personal"
Villa Gregorio
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Frequently asked questions

How much does it cost to stay in a 4-star hotel in Cayo Guillermo?
We can help you quickly locate the ideal 4-star hotel for your vacation in Cayo Guillermo. Use our handy filter tool to fine-tune your search by things like price, conveniences and property star rating and get access to awesome deals in a few clicks.

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What's the difference between 5-star and 4-star hotels in Cayo Guillermo?
If you choose to spend your vacation at a 4-star hotel in Cayo Guillermo, you’ll usually find lots of conveniences to keep you comfortable, such as a restaurant, pool and gym. You can experience top-quality service and upscale accommodations. Go for a 5-star hotel and you’ll get a few more bells and whistles — think on-site spas, concierge assistance and indulgent turndown services. You’ll most likely get more amenities and exclusive services at a 5-star getaway, but both are awesome options for luxury travelers.
Does Cayo Guillermo have any 4-star all-inclusive resorts?
Enjoy a stress-free vacation experience where just about everything is included in one upfront price by using our “All inclusive” filter. Budgeting is a breeze when your room, food, activities and entertainment are already taken care of. After something a little different? Check out the great deals on our standard 4-star options in and around Cayo Guillermo too.