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Check prices for these dates

Tonight
16 Feb - 17 Feb
Tomorrow
17 Feb - 18 Feb
Next weekend
21 Feb - 23 Feb
In two weeks
28 Feb - 2 Mar

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Compare 3 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

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Learn more about Cayo Santa Maria

Escape to Cayo Santa Maria! Enjoy its beaches.

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Frequently asked questions

Where is the best place for a stay in Cayo Santa Maria?

Based on our traveler data, Grand Memories Santa Maria - All Inclusive is one of the top choices for your stay. This property offers 5 restaurants and free breakfast. Other good choices for your trip include Villa Gaviota Cayo Coco and Sanctuary at Grand Memories Santa Maria - Adults Only - All Inclusive. See all available top hotels, or vacation rentals in Cayo Santa Maria.

If I need to cancel my hotel reservation in Cayo Santa Maria, will I receive a refund?

Yes, you'll find most hotel reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Cayo Santa Maria.

Where can I learn more about changing or cancelling my trip to Cayo Santa Maria?

To find more details about rescheduling or cancelling your trip to Cayo Santa Maria, head over to our customer service page.

What's the best all-inclusive hotel in Cayo Santa Maria?

Grand Memories Santa Maria - All Inclusive is an all-inclusive property featuring 5 restaurants and a children's pool, and a favorite with Expedia travelers. Sanctuary at Grand Memories Santa Maria - Adults Only - All Inclusive is another good choice for your stay. See more all-inclusive resorts in Cayo Santa Maria.

Where is the best hotel to stay close to Playa Las Gaviotas?

Grand Memories Santa Maria - All Inclusive is one of the top choices for your stay based on our traveler data, and this 3.5-star property offers 5 restaurants and free breakfast. It's located 4.3 mi (6.9 km) from Playa Las Gaviotas. Another good option is Sanctuary at Grand Memories Santa Maria - Adults Only - All Inclusive, located 4.2 mi (6.7 km) away.

What's the best place to stay near Juan Gualberto Gomez Airport (VRA)?

Canimao is one of the top choices for your stay and is a popular hotel, featuring a restaurant and an outdoor pool. It's located 3.7 mi (6 km) from Juan Gualberto Gomez Airport.

How is it to stay in Cayo Santa Maria?

Visitors can enjoy all that Cayo Santa Maria has to offer including its beaches. In Cayo Santa Maria, there are 3 hotels and other accommodations to choose from. Find out more about Cayo Santa Maria.

What are the top places to visit in Cayo Santa Maria?

A favorite place to visit is Playa Las Gaviotas. Check out what more to see and do in Expedia's Cayo Santa Maria guide.

What's the seasonal weather like in Cayo Santa Maria?

The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and March with an average of 75°F. Average annual precipitation for Cayo Santa Maria is 39 inches.