Find All Upstate South Carolina Hotels
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Find All Upstate South Carolina Hotels
We have found 2590 Upstate South Carolina Hotels
- Whole Hearts Bed and Breakfast
- ✨ Steps from the Swamp Rabbit Trail, Tandem Coffee, Topsoil and more.
- Red Roof Inn & Suites Duncan
- Peaceful Lakefront Getaway Close to Clemson
- Holy Cow Farms a large modern Farm House.11 miles from Tryon TIEC. Pool & HotTub
- Boutique hotel in historic downtown Seneca. Room #2 Owners Suite. Q/K combo.
- Quiet farmhouse nestled near Presbyterian College and Clinton, SC w/pool table.
- Budget Inn Express
- Studio 6 Greenville, SC - I-85 Near Downtown
- Historic B&B with delicious meals in charming Anderson
- Enchanting Historical1906 Modern Farmhouse: Perfect Blend of History and Comfort
- 88-acre w/ Lodge, pavilion, and lake in SC! Sit back and relax at VSL!
- InTown Suites Extended Stay Anderson SC - Clemson University
- 7 BR Bunk House in Cozy Campobello Sleeps 28
- Tucker Farm Cottage on Century Farm
- AUG/SEPT SALE FIREPIT TREE-FORT RETREAT 6 miles to Reedy Falls, 1.5 to Conastee
- Boutique hotel in historic downtown Seneca. Room#1, Q/K combo.
- Poolside Mountain Views and Outdoor Living
- Suburban Studios Spartanburg - I-26
- Light and airy contemporary guest house with private deck and parking.
- Quiet, scenic farm with private Pool! Minutes from Greer and Greenville, SC.
- Charming 1850 antebellum B&B, minutes from Anderson University and Clemson.
- Historic Bed and Breakfast, sleeps 12-16
- Moments Happen Here: 10 acres
- Countryside Haven
- Bright and beautiful Cottage near Spartanburg , Tryon Intl Eq Center, Asheville.
- Clean, Modern Guest Suite - Please see description
- Relax Inn Westminster
- Equestrian Home & Cottage
- Quality Inn Clemson Near University
- Keowee Cove Dock & Lake Views!
- Stay at our luxury mountain home w/ western views of the Blue Ridge mountains.
- Super 8 by Wyndham Spartanburg/I-26 Exit 22
- Downtown Greenville Lux Carriage House—Walk to Main St, SR Trail, The Well Arena
- Royal Inn
- Lake Keowee Cabin: Peaceful and Bright
- Magnolia Inn
- Budget Inn
- Cozy 2-bedroom Rooftop apartment in charming Old Mill Village, Campobello