Find 5 Star Hotels in Santa Clara from AED 295

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Compare Santa Clara 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Riu Plaza Panama
Front of property

Hotel Riu Plaza Panama

5.0 star property
9.0 out of 10, Wonderful, (3331)
"Everything was ready "
The price is AED 386
AED 424 total
includes taxes & fees
16 Dec - 17 Dec
Hotel Riu Plaza Panama
Waldorf Astoria Panama
Room

Waldorf Astoria Panama

5.0 star property
9.0 out of 10, Wonderful, (997)
"My hubby and i stayed during our 16 yr anniversary. The staff was very helpful in every way. William in the restaurant made our stay even more comfortable and enjoyable because he spoke English and was such a excellent host greeting us everyday and giving us his best recommendations. Thank you so much William. You are the best!"
The price is AED 555
AED 611 total
includes taxes & fees
20 Dec - 21 Dec
Waldorf Astoria Panama
JW Marriott Panama
Pool

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1010)
"Panama is great! JJ"
The price is AED 555
AED 601 total
includes taxes & fees
13 Dec - 14 Dec
JW Marriott Panama
W Panama
Exterior

W Panama

5.0 star property
8.8 out of 10, Excellent, (1009)
"Lo único que puedo decir es que el baño mejor la ducha tiene moho. Todo lo demás estuvo muy lindo y bueno"
The price is AED 408
AED 442 total
includes taxes & fees
14 Dec - 15 Dec
W Panama
Hilton Panama
Room

Hilton Panama

5.0 star property
8.8 out of 10, Excellent, (1036)
"It's centrally located in a nice area"
The price is AED 500
AED 549 total
includes taxes & fees
14 Dec - 15 Dec
Hilton Panama
The Westin Playa Bonita Panama
Exterior

The Westin Playa Bonita Panama

5.0 star property
8.0 out of 10, Very Good, (1003)
"Everything was perfect ! I really enjoyed this resort "
The price is AED 611
AED 663 total
includes taxes & fees
6 Dec - 7 Dec
The Westin Playa Bonita Panama
Sofitel Legend Casco Viejo, Panama City
Exterior detail

Sofitel Legend Casco Viejo, Panama City

5.0 star property
9.8 out of 10, Exceptional, (337)
"Lovely hotel in great location with very attentive staff. Highly recommended "
The price is AED 1,074
AED 1,182 total
includes taxes & fees
19 Dec - 20 Dec
Sofitel Legend Casco Viejo, Panama City
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Pool

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
9.6 out of 10, Exceptional, (514)
"Amazing "
The price is AED 584
AED 642 total
includes taxes & fees
13 Dec - 14 Dec
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Veneto Hotel & Casino
Pool

Veneto Hotel & Casino

5.0 star property
6.2 out of 10, (997)
"Actually didn't stay, the hotel is closed and out of business"
Veneto Hotel & Casino
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santa Clara.
Crowne Plaza Panama Airport, an IHG Hotel

Crowne Plaza Panama Airport, an IHG Hotel

Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
The price is AED 396 per night from Dec 1 to Dec 2
AED 396
AED 436 total
includes taxes & fees
1 Dec - 2 Dec
8.2/10 Very Good! (1,995 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the best 5-star hotels in Santa Clara?
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City is a top option around the Panama City neighborhood of Santa Clara based on Expedia guest reviews. From its first-in-class services to its superior amenities, this 5-star hotel promises a lavish and comfortable stay.
How much does it cost to stay in a 5-star hotel in Santa Clara?
The amount you pay for a 5-star hotel in Santa Clara depends on things like when you plan to travel and the length of your escape. Our top tip for landing the best deal? Use our pricing filters to check out all of the available options for your chosen dates.

  • Search for the lowest price per night from AED 295

What makes a hotel 5 stars in Santa Clara?
Outstanding guest service is the defining feature of every 5-star hotel in Santa Clara. From the moment you enter the lobby, staff ensure your every need is met, whether recommending activities and tours or providing a nightly turn-down service. In addition, hotels must offer top-rate amenities to be entitled to a 5-star rating. These can include luxury bath products, saunas or spas, pools, gastronomic restaurants and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Santa Clara?
Find a luxurious escape that includes your room, meals, activities and entertainment in Santa Clara with our filter tool. Search for resorts with a 5-star rating and select the “All inclusive” filter. Be sure to check what’s included in the price. That way, you’ll be ready to maximize the many perks on offer from the moment you step into the lobby.
What are the top 5-star spa hotels in Santa Clara?
Among the finest spa properties around Santa Clara, The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City is where you can leave behind the worries of daily life. Choose this 5-star option and indulge in a variety of treatments and activities that aim to enhance your well-being.
Are there any 5-star vacation rentals in Santa Clara?
Although you won’t find any 5-star vacation rentals in Santa Clara on our site, we have a range of properties that promise a terrific getaway. Find one that matches your style by searching our vacation rentals in Santa Clara.