Find 5 Star Hotels in Central West End, MO from AED 323
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check availability on Central West End 5 Star Hotels
Compare Central West End 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Four Seasons Hotel St Louis
Four Seasons Hotel St Louis
9.4 out of 10, Exceptional, (997)
The price is AED 1,545
AED 1,807 total
includes taxes & fees
17 Apr - 18 Apr

The Ritz-Carlton, St. Louis
The Ritz-Carlton, St. Louis
9.2 out of 10, Wonderful, (527)
The price is AED 2,127
AED 2,477 total
includes taxes & fees
10 Apr - 11 Apr
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Central West End.

Hyatt Regency St. Louis at The Arch
315 Chestnut St, St. Louis, MO
The price is AED 386 per night from Apr 18 to Apr 19
AED 386
AED 455 total
includes taxes & fees
18 Apr - 19 Apr
8.4/10 Very Good! (3,615 reviews)
Still don't see what you're looking for?
See all properties in Central West End.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Central West End
Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

Explore a world of travel with Expedia
Explore a world of travel with Expedia
Central West End Hotels by Star Rating
Hotels in Central West End Neighborhoods
Stay near popular Central West End attractions
- Hotels near Barnes Jewish Hospital
- Hotels near Cathedral Basilica of St. Louis
- Hotels near World Chess Hall of Fame
- Hotels near Enterprise Center
- Hotels near St. Louis Union Station
- Hotels near Busch Stadium
- Hotels near Gateway Arch
- Hotels near St. Louis Zoo
- Hotels near Washington University in St. Louis
- Hotels near Forest Park
- Hotels near City Museum
- Hotels near St. Louis University
- Hotels near Dome at America’s Center
- Hotels near America's Center Convention Complex
- Hotels near Hollywood Casino Amphitheatre
- Hotels near Fox Theater
- Hotels near Ameristar Casino St. Charles
- Hotels near Mississippi River
- Hotels near Westport Plaza
- Hotels near Horseshoe St. Louis Casino
More Hotel Options in Central West End
- Adventure Hotels in Central West End
- Business Hotels in Central West End
- Casinos in Central West End
- Cheap Hotels in Central West End
- Family Hotels in Central West End
- Golf Hotels in Central West End
- Historic Hotels in Central West End
- Hotel Wedding Venues in Central West End
- Hotel with a Concierge in Central West End
- Hotels with Bars in Central West End
- Hotels with Free Parking in Central West End
- Hotels with Hot Tubs in Central West End
- Hotels with WiFi in Central West End
- Hotels with a Pool in Central West End
- Hotels with an Indoor Pool in Central West End
- Hotels with smoking rooms in Central West End
- Luxury Hotels in Central West End
- Pet-friendly Hotels in Central West End
- Resorts & Hotels with Spas in Central West End
- Romantic Hotels in Central West End
- Shopping Hotels in Central West End
Explore more hotels
- Moonrise Hotel
- Hampton Inn St. Louis-Downtown (At the Gateway Arch)
- River City Casino & Hotel
- Hollywood Casino & Hotel St. Louis
- Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
- Le Méridien St. Louis Clayton
- 21C Museum Hotel St Louis
- Ameristar Casino Resort and Spa
- Live by Loews - St.Louis
- Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
- Hilton St. Louis at the Ballpark
- Casino Queen Hotel
- Embassy Suites by Hilton St. Louis Downtown
- Pear Tree Inn St. Louis Airport
- Drury Inn & Suites St. Louis Union Station
- Best Western St. Louis-Kirkwood Route 66
- La Quinta Inn & Suites by Wyndham St. Louis Westport
- Pear Tree Inn St. Louis Near Union Station
- Wingate by Wyndham St. Louis/Fenton Route 66
- Wingate by Wyndham St. Louis Airport