Find 5 Star Hotels in Central West End, MO from AED 382
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check availability on Central West End 5 Star Hotels
Compare Central West End 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Four Seasons Hotel St Louis
Four Seasons Hotel St Louis
9.4 out of 10, Exceptional, (1000)
The price is AED 1,623
AED 1,898 total
includes taxes & fees
16 May - 17 May

The Ritz-Carlton, St. Louis
The Ritz-Carlton, St. Louis
9.2 out of 10, Wonderful, (529)
The price is AED 1,980
AED 2,306 total
includes taxes & fees
8 May - 9 May
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Central West End.

Hyatt Regency St. Louis at The Arch
315 Chestnut St, St. Louis, MO
The price is AED 400 per night from Jun 1 to Jun 2
AED 400
AED 472 total
includes taxes & fees
1 Jun - 2 Jun
8.4/10 Very Good! (3,650 reviews)
Still don't see what you're looking for?
See all properties in Central West End.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Central West End
Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

Explore a world of travel with Expedia
Explore a world of travel with Expedia
Central West End Hotels by Star Rating
Hotels in Central West End Neighborhoods
Stay near popular Central West End attractions
- Hotels near Barnes Jewish Hospital
- Hotels near Cathedral Basilica of St. Louis
- Hotels near World Chess Hall of Fame
- Hotels near Enterprise Center
- Hotels near Busch Stadium
- Hotels near St. Louis Union Station
- Hotels near St. Louis Zoo
- Hotels near Gateway Arch
- Hotels near Washington University in St. Louis
- Hotels near Forest Park
- Hotels near Hollywood Casino Amphitheatre
- Hotels near City Museum
- Hotels near Dome at America’s Center
- Hotels near Ameristar Casino St. Charles
- Hotels near St. Louis University
- Hotels near Mississippi River
- Hotels near Fox Theater
- Hotels near America's Center Convention Complex
- Hotels near Westport Plaza
- Hotels near Horseshoe St. Louis Casino
More Hotel Options in Central West End
- Adventure Hotels in Central West End
- Business Hotels in Central West End
- Casinos in Central West End
- Cheap Hotels in Central West End
- Family Hotels in Central West End
- Golf Hotels in Central West End
- Historic Hotels in Central West End
- Hotel Wedding Venues in Central West End
- Hotel with a Concierge in Central West End
- Hotels with Bars in Central West End
- Hotels with Free Parking in Central West End
- Hotels with Hot Tubs in Central West End
- Hotels with WiFi in Central West End
- Hotels with a Pool in Central West End
- Hotels with an Indoor Pool in Central West End
- Hotels with smoking rooms in Central West End
- Luxury Hotels in Central West End
- Pet-friendly Hotels in Central West End
- Resorts & Hotels with Spas in Central West End
- Romantic Hotels in Central West End
- Shopping Hotels in Central West End
Explore more hotels
- Clayton Plaza Hotel & Extended Stay
- River City Casino & Hotel
- Pear Tree Inn St. Louis Airport
- Sonesta ES Suites St. Louis - Chesterfield
- Pear Tree Inn St. Louis Near Union Station
- Best Western St. Louis-Kirkwood Route 66
- Hilton St. Louis Airport
- Hampton Inn St. Louis-Downtown (At the Gateway Arch)
- 21C Museum Hotel St Louis
- Ameristar Casino Resort and Spa
- Live by Loews - St.Louis
- Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
- Moonrise Hotel
- Le Méridien St. Louis Clayton
- Hilton Pennywell St. Louis at the Arch
- Hilton St. Louis at the Ballpark
- Renaissance St. Louis Airport Hotel
- Days Inn and Suites by Wyndham St. Louis/Westport Plaza
- Forest Park Hotel by MDR
- Embassy Suites by Hilton St. Louis Downtown