Find 4 Star Hotels in Edisto Island, SC
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check availability on Edisto Island 4 Star Hotels
Compare Edisto Island 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Edisto Island Hotels by Star Rating
Stay near popular Edisto Island attractions
- Hotels near Edisto Beach State Park
- Hotels near Botany Bay Plantation
- Hotels near Plantation Course at Edisto
- Hotels near Botany Bay Plantation Heritage Preserve and Wildlife Management Area
- Hotels near Edisto Island Museum
- Hotels near Edisto Island Serpentarium
- Hotels near With These Hands Gallery
- Hotels near Marine Corps Air Station Beaufort
- Hotels near Bay Street
- Hotels near Folly Beach Fishing Pier
- Hotels near Angel Oak Tree
- Hotels near James Island County Park
- Hotels near The Ocean Course
- Hotels near University of South Carolina-Beaufort
- Hotels near Freshfields Village
- Hotels near Turtle Point Golf Course
- Hotels near Beaufort National Cemetery
- Hotels near Citadel Mall
- Hotels near Bohicket Marina
- Hotels near Henry C. Chambers Waterfront Park
More Hotel Options in Edisto Island
- Adventure Hotels in Edisto Island
- Beach Hotels in Edisto Island
- Business Hotels in Edisto Island
- Family Hotels in Edisto Island
- Golf Hotels in Edisto Island
- Historic Hotels in Edisto Island
- Hotels with Bars in Edisto Island
- Hotels with Free Parking in Edisto Island
- Hotels with Hot Tubs in Edisto Island
- Hotels with WiFi in Edisto Island
- Hotels with a Pool in Edisto Island
- Romantic Hotels in Edisto Island
- Shopping Hotels in Edisto Island
More Accommodation Types in Edisto Island
Explore more hotels
- Plantation Nest-The Kerryman2. Screened porch overlooking 5th Tee Box
- Ocean's Eleven Edisto - Cozy Cottage 1 block from the beach!
- Dog-Friendly Home Right On Beach w/ Private Washer/Dryer & Free WiFi
- Oceanfront house with ocean views & beach access - near dining & golf
- Coastal townhome with riverfront views, deck, & W/D - pool and athletic courts
- The Edisto Escape 5 Min Drive From Beach - 3bdrm, sleeper, NEW Queen Beds!
- Blessed Rest
- Cozy Edisto Condo-Close to the Beach!
- Sunny beach house with ocean view, large deck, central AC, & washer/dryer
- Quiet, oceanfront home with W/D, balcony, patio & great views - dog-friendly
- 4 bedrooms, Gorgeous Ocean Views, fireplace, entertainment room with BIG TV!
- Drifting to Driftwood- Wyndam Resort Condo on Golf Course! New 75" TV!
- Dog-friendly beach home with screened porch, charming interior, & W/D
- Ocean-view dog-friendly home across street from beach with private pool, W/D, AC
- Dog-Friendly House Right On Sand w/ Patio, Private W/D, & Free WiFi
- Beautiful Home Right On the Beach w/ Private W/D, Free WiFi, & Patio
- SEABATICAL. Lovely beach house steps to the beach with private pool
- Dog-Friendly, Oceanside House w/Private Washer/Dryer, Free WiFi, Patio
- Cozy home sleeps 4 & just a few steps to the beach & Linens Included!
- New rental overlooking Plantation Course 9th tee box. 1500 sq feet, smoke free.