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Compare 120 Vacation Homes in Wykoff with updated reviews, rates, and availability.

Park-Side, Easy Access To Downtown, Mayo Clinic & Bike Trail, Family-Friendly
Eat-in kitchen
Park-Side, Easy Access To Downtown, Mayo Clinic & Bike Trail, Family-Friendly
9.8 out of 10, Exceptional, (52)
"We had to gather a lot of family on short notice to say goodbye to a dying family member and this space was perfect for us all to gather and grieve together. There was plenty of sleeping space for everyone and it was conveniently lovlcated near parks and walking trails for our kiddos."
Park-Side, Easy Access To Downtown, Mayo Clinic & Bike Trail, Family-Friendly
Welcoming mid-century modern history-friendly home in bluff county.
This bright, romantic master is the perfect place to relax. Winter shown here.
Welcoming mid-century modern history-friendly home in bluff county.
10.0 out of 10, Exceptional, (21)
"House is clean and comfortable. Tammy is very easy to communicate with. The location is convenient to many areas of interest in the region. "
Welcoming mid-century modern history-friendly home in bluff county.
Lots of charm and only blocks away from the Root River and Bike trails
Exterior detail
Lots of charm and only blocks away from the Root River and Bike trails
10.0 out of 10, Exceptional, (14)
"Pauline was very kid and helpful the was clean cozy. It was a great Location for the funneral we had to tend to. I alos live all the bored games great safe family atopmshere "
Lots of charm and only blocks away from the Root River and Bike trails
Root River Retreat
Living room / family room . Sofa, chairs , pub table and Tv
Root River Retreat
9.6 out of 10, Exceptional, (35)
"Lori is a wonderful host - the property is just as described and extremely clean. The 2 bedrooms are beautiful with plenty of natural light. The main area has all you need for a long weekend - a couch, 2 comfortable chairs, high top table, sizeable fridge/freezer, breakfast bar area, ginormous TV...all very comfortable! There is garage space to store bikes, if you are in the area for cycling. The home is located in a quiet neighborhood with easy access to all the surrounding communities. Lori...
Root River Retreat
Fresh space near Mayo Clinic and downtown
Living room, which is open to the dining room
Fresh space near Mayo Clinic and downtown
9.6 out of 10, Exceptional, (16)
"Very clean property. It was comfortable and cute. The owners were responsive to us and so helpful"
Fresh space near Mayo Clinic and downtown
Single Level Living with Comfortable Recliners
Open concept living. A third chair has been added by the lamp.
Single Level Living with Comfortable Recliners
10.0 out of 10, Exceptional, (29)
"This was our very first experience with a VRBO. It exceeded our expectations in every aspect including but not limited to the following: communicating with the property manager, cleanliness, kitchen supplies, bathroom accessories, up to date appliances, comfy recliners, easy instructions for TV/cable remotes… The host was responsive to short notice special requests we were in need of as well. This property definitely felt like “home away home”…good “vibes”. Quiet neighborhood with easy...
Single Level Living with Comfortable Recliners
Century Cottage-PERFECT for Mayo & downtown visitors!
Cozy and spacious
Century Cottage-PERFECT for Mayo & downtown visitors!
10.0 out of 10, Exceptional, (101)
"We had a girls weekend and did some baking and shopping"
Century Cottage-PERFECT for Mayo & downtown visitors!
Delightful family home near pool, playground, park, nature center 1.6 mi to Mayo
Home Front
Delightful family home near pool, playground, park, nature center 1.6 mi to Mayo
10.0 out of 10, Exceptional, (23)
"A family member had several day appointments at the Mayo. He has mobility iaauws. Thia home eas perfect. 1 level. Walk-in shower. Bed with head and feet incline."
Delightful family home near pool, playground, park, nature center 1.6 mi to Mayo
2023 Construction, 5 BR, Gym, Game Area
Living room
2023 Construction, 5 BR, Gym, Game Area
10.0 out of 10, Exceptional, (14)
"The best luxurious home in Rochester MN "
2023 Construction, 5 BR, Gym, Game Area
Custom Kitchen, Game Room, Cozy & Spacious
Walk into your vacation home with custom-built features!
Custom Kitchen, Game Room, Cozy & Spacious
10.0 out of 10, Exceptional, (39)
"The house was amazing, the kitchen was huge, and the game room in the garage was a nice bonus. "
The price is AED 485
AED 881 total
includes taxes & fees
22 Dec - 23 Dec
Custom Kitchen, Game Room, Cozy & Spacious
Kutzky Cottage // 3 BR, 4 Blocks to Mayo, Family & Pet Friendly, Fenced Yard
Living area
Kutzky Cottage // 3 BR, 4 Blocks to Mayo, Family & Pet Friendly, Fenced Yard
10.0 out of 10, Exceptional, (8)
"Beautiful property. Very clean and well organized. Great space for our dog!"
Kutzky Cottage // 3 BR, 4 Blocks to Mayo, Family & Pet Friendly, Fenced Yard
City Hall Recorder's Office
Living Area
City Hall Recorder's Office
2.0 star property
10.0 out of 10, Exceptional, (2)
"We were there for the Mayo experience. We walked pretty much every day. Only a 10 minute walk to most of the buildings. Lots of good food within walking distance too"
The price is AED 261
AED 744 total
includes taxes & fees
27 Nov - 28 Nov
City Hall Recorder's Office
"Walden Pond" Adventure Amidst 44 Private Acres
Enjoy the comfort and beauty of the inside and the awesome adventure outside.
"Walden Pond" Adventure Amidst 44 Private Acres
10.0 out of 10, Exceptional, (118)
"Really enjoyed the stay. It was very relaxing and a lot of fun"
"Walden Pond" Adventure Amidst 44 Private Acres
☆Dee Dee's Den: A Dharma Dwellings Parent Company☆
Welcome to Dee Dee's Den! We are pleased to offer this home for you!
☆Dee Dee's Den: A Dharma Dwellings Parent Company☆
10.0 out of 10, Exceptional, (22)
"Every year my friends and family travel for a week. We are Combat Veterans, ranging from the Vietnam War to the Iraq and Afghanistan wars. This was the best house we have ever stayed in."
☆Dee Dee's Den: A Dharma Dwellings Parent Company☆
Park in the Garage and Walk to Mayo Clinic
King size bed with memory foam mattress in primary bedroom located upstairs.
Park in the Garage and Walk to Mayo Clinic
10.0 out of 10, Exceptional, (51)
"We stayed during medical visits at Mayo and enjoyed being able to walk to the clinic, come back and relax in such a comfortable place. Excellent communication from Jill, the owner, "
Park in the Garage and Walk to Mayo Clinic
Cozy house / small town living. Attractions include trout capital of Minnesota
Exterior
Cozy house / small town living. Attractions include trout capital of Minnesota
5.6 out of 10, (8)
"We came up for the weekend for our fanily reunion . The house is old & smells like an old house, which isn't a bad thing. The house was clean & tidy. We couldn't find the hot tub,but it was all good. We didn't spend much time at the house, except for sleeping & watching tv in the evening. Thank you for a pleasant stay."
Cozy house / small town living. Attractions include trout capital of Minnesota
Silver Lake Oasis
Silver Lake Oasis
Silver Lake Oasis
9.6 out of 10, Exceptional, (33)
"Cozy, mostly modern, except for the bathroom. Steep stairs to the bedroom. Love the location. Made a few casts from shore, but didn't catch any fish. Walk around to the lakefront a bit steep and unsteady. Otherwise, enjoyed our stay!"
Silver Lake Oasis
Charming Rochester Home - 2 Mi to Mayo Clinic!
Rochester Vacation Rental | 3BR | 1BA | 1,900 Sq Ft | 2 Steps to Entrance
Charming Rochester Home - 2 Mi to Mayo Clinic!
9.8 out of 10, Exceptional, (14)
"The house is perfect for a larger family. It had all the amenities of home and we enjoyed the game room in the basement. The property managers were responsive and very helpful. Would 100% stay again if in the area."
Charming Rochester Home - 2 Mi to Mayo Clinic!
3 blk St Mary 11 Mayo Pet Friendly Covered ByFaith
Front view
3 blk St Mary 11 Mayo Pet Friendly Covered ByFaith
9.6 out of 10, Exceptional, (22)
"The location is very central to Mayo and shopping. The neighborhood was quiet. I will stay there again."
The price is AED 334
AED 935 total
includes taxes & fees
24 Nov - 25 Nov
3 blk St Mary 11 Mayo Pet Friendly Covered ByFaith
Charming 2 Bed 1 Bath Home W/Fully Fenced in Back yard
Living area
Charming 2 Bed 1 Bath Home W/Fully Fenced in Back yard
9.4 out of 10, Exceptional, (11)
"Perfect size and proximity to Mayo Clinic and walking trails along the river. Would stay there agsin."
The price is AED 404
AED 1,087 total
includes taxes & fees
30 Nov - 1 Dec
Charming 2 Bed 1 Bath Home W/Fully Fenced in Back yard
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in Wykoff

Welcoming mid-century modern history-friendly home in bluff county.
This bright, romantic master is the perfect place to relax. Winter shown here.
Welcoming mid-century modern history-friendly home in bluff county.
10.0 out of 10, Exceptional, (21)
"House is clean and comfortable. Tammy is very easy to communicate with. The location is convenient to many areas of interest in the region. "
Welcoming mid-century modern history-friendly home in bluff county.
The Berkman
Lobby
The Berkman
3.0 star property
9.6 out of 10, Exceptional, (254)
"Clean & enjoyable stay. "
The price is AED 615
AED 715 total
includes taxes & fees
13 Dec - 14 Dec
The Berkman
Heritage hideaway-Secluded Log Cabin
Front patio area with charcoal grill
Heritage hideaway-Secluded Log Cabin
10.0 out of 10, Exceptional, (357)
"My wife and I stayed here a few years ago and loved everything about this place, so when the opportunity came for me to take a vacation on my own, I knew where I was going. It's so nuce how quuet and secluded it is here. You'll have basically everything you need for a nice stay here. "
Heritage hideaway-Secluded Log Cabin
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.