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Compare 147 Vacation Homes in Wykoff with updated reviews, rates, and availability.

Century Cottage-PERFECT for Mayo & downtown visitors!

10.0 out of 10, Exceptional, (111)
"Perfect home away from home!"
Century Cottage-PERFECT for Mayo & downtown visitors!

Delightful family home near parks, nature center, 1.5 m to Mayo Clinic downtown

10.0 out of 10, Exceptional, (37)
"Had a surgery at Mayo and family needed a place to stay. Everyone has their own room, plenty of seating for meals and tv. Kitchen is well equipped. Great customer service by the owners."
Delightful family home near parks, nature center, 1.5 m to Mayo Clinic downtown

Entertainment for the whole family. Sleeps up to 10.

10.0 out of 10, Exceptional, (2)
"Arrived at 4pm and the house was all ready for us. House was located in q quiet neighborhood. Pictures were an accurate description of the house. Communication with the owner was quick and smooth. House had a great floorplan and you could see from the front room all the way to the kitchen which was great when traveling with a toddler. Extra bonus points for the permanent gate at the top of the stairs. Kitchen was stocked with plenty of everything you would need plus quite the selection of...
Entertainment for the whole family. Sleeps up to 10.

Park-Side, Easy Access To Downtown, Mayo Clinic & Bike Trail, Family-Friendly

9.8 out of 10, Exceptional, (57)
"Couldn't love this location for us more. The park was so close. House was quiet. Wish there had been pickleball gear for the brand new courts across the bridge! "
Park-Side, Easy Access To Downtown, Mayo Clinic & Bike Trail, Family-Friendly

Fresh space near Mayo Clinic and downtown

9.4 out of 10, Exceptional, (18)
"Very clean property. It was comfortable and cute. The owners were responsive to us and so helpful"
Fresh space near Mayo Clinic and downtown

Magical Nest Hideaway

10.0 out of 10, Exceptional, (113)
"Stayed a couple days. Nice location and friendly owners. "
Magical Nest Hideaway

Within walking distance of all the amenities! Bike the trail~ float the river

10.0 out of 10, Exceptional, (11)
"We all talked about how clean and relaxing the home was…very clean, updated, well stocked and awesome location. "
Within walking distance of all the amenities! Bike the trail~ float the river

2 Bedroom Apartment, Walk To Mayo, Free Parking

2.0 star property
10.0 out of 10, Exceptional, (1)
"My husband was being seen at Mayo Clinic this past week. This place is walking distance (if you are able) to walk to and from the main hospital (Mayo & Gonda). It made our stay easier knowing how close our place was. The staff was really quick to respond if/when we had questions or needed something. Will be staying here again! "
2 Bedroom Apartment, Walk To Mayo, Free Parking

The Little House // Stylish & Cozy ~ 2 mi from Mayo Clinic

10.0 out of 10, Exceptional, (10)
"Ideal for travelers with pets "
The Little House // Stylish & Cozy ~ 2 mi from Mayo Clinic

Charming 2-Bedroom house along city trail 1 mile from Mayo Clinic and downtown.

9.8 out of 10, Exceptional, (43)
"This is a wonderful house - great location, very clean, easy access to Mayo Clinic, shopping and restaurants. We will stay again. "
Charming 2-Bedroom house along city trail 1 mile from Mayo Clinic and downtown.

"Walden Pond" Adventure Amidst 44 Private Acres

10.0 out of 10, Exceptional, (124)
"The Bungalow was just what our family needed, a few days away from the hustle and bustle. Really enjoyed the trails (went for walks at least twice a day) and the loft, for hanging out. Would stay again. "
"Walden Pond" Adventure Amidst 44 Private Acres

Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.

10.0 out of 10, Exceptional, (76)
"The house is very nice, having been remodeled and tastefully decorated. The owners have done an excellent job, and have a great eye for detail. The bed was very comfortable, and the house very clean. Communication was great, The neighborhood is quiet, and very close to hospitals and downtown Rochester. We come to Rochester a couple of times a year and will definitely look at renting agin on a future visit. "
Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.

Newly remodeled "Beach" Themed home that is close to downtown and Mayo Clinic.

10.0 out of 10, Exceptional, (5)
"House was exactly as described, very clean, quiet and cozy. Was perfect for my short stay visiting family. Would absolutely stay again. "
Newly remodeled "Beach" Themed home that is close to downtown and Mayo Clinic.

☆Dee Dee's Den: A Dharma Dwellings Parent Company☆

10.0 out of 10, Exceptional, (32)
"This was our first time using a Vrbo accommodation and I don’t think we will be returning to hotels if we can be guaranteed the same host. Our trip was a health-related one so proximity to Mayo and comfort was key for a family of four and one fur baby. Alex was always available and prompt to our queries. We felt valued as guests and overall very much at home. The property is huge (perfect for large families) and well maintained. Thankfully, our trip had a good outcome on all ends and are forever...
☆Dee Dee's Den: A Dharma Dwellings Parent Company☆

Historic City Hall Recorder's Office - ADA Accessible

2.0 star property
10.0 out of 10, Exceptional, (7)
"Exactly as described, they were so accommodating, i was there for medical testing at Mayo and on the morning of checkbout a friend who traveled with me got sick and we needed to extend our syay for her to rest, they were quick to respond to messages and made the extension of stay super easy. Thank you so much for being great hosts! Ill be back when i return to mayo this is the only place i want to stay."
Historic City Hall Recorder's Office - ADA Accessible

Silver Lake Oasis

9.6 out of 10, Exceptional, (34)
"We wanted a week to step back. This worked nicely. It has a gorgeous lake view and it's a short drive to many restaurants and shops."
Silver Lake Oasis

Discounted Charming 2-bedroom house in Rochester

10.0 out of 10, Exceptional, (1)
"Needed a last minute place to stay with my elderly parents for Mayo appointments. The home was clean, cute, location great, easy to find--very homey."
Discounted Charming 2-bedroom house in Rochester

Charming 2 Bed 1 Bath Home W/Fully Fenced in Back yard

9.4 out of 10, Exceptional, (16)
"Quick visit to Rochester to celebrate Easter with our grandkids. Had a nice Easter egg hunt in the backyard and enjoyed the park across the road. "
Charming 2 Bed 1 Bath Home W/Fully Fenced in Back yard

A Restful Retreat - Walk to Mayo - Free Parking

2.0 star property
10.0 out of 10, Exceptional, (5)
"Relaxing 2 nites away.Was perfect little getaway."
A Restful Retreat - Walk to Mayo - Free Parking

2 Blks St Marys Main Fl Beds Bath CoveredByFaith

10.0 out of 10, Exceptional, (93)
"Good location and safe quite neighborhood!"
2 Blks St Marys Main Fl Beds Bath CoveredByFaith
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in Wykoff

The Berkman

3.0 star property
9.6 out of 10, Exceptional, (285)
"Great Place."
The price is AED 389
AED 452 total
includes taxes & fees
16 May - 17 May
The Berkman

Heritage hideaway-Secluded Log Cabin

10.0 out of 10, Exceptional, (366)
"Very nice cabin, with fantastic views "
Heritage hideaway-Secluded Log Cabin

Root River Valley Cabin ~ Lanesboro, MN

10.0 out of 10, Exceptional, (302)
"We very much enjoyed our stay. The cabin was clean and well stocked. It was spacious while also feeling cozy. "
Root River Valley Cabin ~ Lanesboro, MN
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.