Midtown, MO

St. Louis

Midtown
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Photo by Karissa Krull
Photo by Linda Garrison
Photo by Sophie R

Popular places to visit


Midtown Hotel Deals

Residence Inn by Marriott St Louis Downtown
Residence Inn by Marriott St Louis Downtown
3 out of 5
525 S Jefferson Ave, St. Louis, MO
The price is AED 466 per night from Apr 6 to Apr 7
AED 466
AED 555 total
includes taxes & fees
6 Apr - 7 Apr
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the breakfast ...
7.8/10 Good! (1,000 reviews)
"Our check-in was very easy and smooth. The room was clean, and very convenient with the sofa bed for our 14 yr old. The area surrounding the hotel is rather industrial but we did not feel unsafe. Conveniently located for our trip to the Arch and City Museum."

Reviewed on 24 March 2025

Residence Inn by Marriott St Louis Downtown
Element St. Louis Midtown
Element St. Louis Midtown
3 out of 5
3763 Forest Park Avenue, St. Louis, MO
The price is AED 514 per night from Apr 6 to Apr 7
AED 514
AED 601 total
includes taxes & fees
6 Apr - 7 Apr
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
9/10 Wonderful! (469 reviews)
"Beautiful hotel with professional and friendly staff. Hotel was very clean, breakfast was delicious with a variety of food choices. Within 10minutes to the majority of the activities we went to. Our room was nice, big enough for our family of 6. Only complaint was housekeeping didn’t tidy up our ..."

Reviewed on 20 March 2025

Element St. Louis Midtown
Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch
4 out of 5
315 Chestnut St, St. Louis, MO
The price is AED 386 per night from Apr 18 to Apr 19
AED 386
AED 455 total
includes taxes & fees
18 Apr - 19 Apr
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (3,537 reviews)
"Great stay!"

Reviewed on 23 March 2025

Hyatt Regency St. Louis at The Arch
Clayton Plaza Hotel & Extended Stay
Clayton Plaza Hotel & Extended Stay
3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
The price is AED 331 per night from Apr 13 to Apr 14
AED 331
AED 386 total
includes taxes & fees
13 Apr - 14 Apr
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,004 reviews)
"It was very clean and the staff were very polite and helpful. I would recommend this hotel to others."

Reviewed on 23 March 2025

Clayton Plaza Hotel & Extended Stay
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3 out of 5
1088 South Highway Drive, Fenton, MO
Fully refundableReserve now, pay when you stay
The price is AED 347 per night from Mar 30 to Mar 31
AED 347
AED 400 total
includes taxes & fees
30 Mar - 31 Mar
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,007 reviews)
"Nice place however we had car trouble and ask for latter check out time from. 11 to 12 I thought being a gold tier member that they would honor that but they did not"

Reviewed on 23 March 2025

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Moonrise Hotel
Moonrise Hotel
4 out of 5
6177 Delmar Blvd, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is AED 493 per night from Mar 30 to Mar 31
AED 493
AED 586 total
includes taxes & fees
30 Mar - 31 Mar
Stay at this 4-star boutique hotel in St. Louis. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the restaurant and the bar in our reviews. ...
9/10 Wonderful! (1,564 reviews)
"The friendly, helpful staff were the most memorable about our stay! Chose this hotel for an easy stroll to a concert venue. It was very convenient and easily accessible on The Loop. Would stay here again!"

Reviewed on 26 March 2025

Moonrise Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Midtown

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The Gate

While there might not be top attractions in The Gate, you can explore the larger area and discover places like St. Louis Union Station and Busch Stadium.

The Gate
St. Louis which includes interior views

Downtown West

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

Downtown West
Lafayette Square which includes a house and a garden

Lafayette Square

The restaurants and shopping are a few reasons travelers visit Lafayette Square. Though there aren't many top sights in the neighborhood, you can visit St. Louis Union Station and Busch Stadium, a few notable attractions nearby.

Lafayette Square
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Shaw

4.5/5(3 area reviews)

While there might not be top attractions in Shaw, you can explore the larger area and discover places like Missouri Botanical Gardens and Arboretum and St. Louis Science Center.

Shaw
Central West End

Central West End

4.5/5(450 area reviews)

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Central West End
Not just bars but also loft apartments are lit in rainbow lights for Pride weekend in the Grove neighborhood in St. Louis! #LifeAtExpedia

The Grove

The Grove might not have many top sights, but St. Louis Zoo and St. Louis Science Center are two attractions nearby that you can check out.

The Grove

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