Search Vacation Homes in Southeast Minnesota

Compare 266 Vacation Homes in Southeast Minnesota with updated reviews, rates, and availability.

Fantastic Large Home Right On Beautiful Lake Pepin!
view of the lake from the chaise lounges

Fantastic Large Home Right On Beautiful Lake Pepin!

10.0 out of 10, Exceptional, (214)
"This property was a perfect fit for a weekend retreat for a group of 12 women"
Fantastic Large Home Right On Beautiful Lake Pepin!
Golf view!
View of golf course from house

Golf view!

10.0 out of 10, Exceptional, (33)
"We will definitely be back again! "
Golf view!
Waterfront Home with HOT TUB, Large Dock, Game Room, Movie Theater
Living area

Waterfront Home with HOT TUB, Large Dock, Game Room, Movie Theater

2.0 star property
10.0 out of 10, Exceptional, (1)
Waterfront Home with HOT TUB, Large Dock, Game Room, Movie Theater
Downtown rambler. 2 bed, 1 bath, office & fence.
Room

Downtown rambler. 2 bed, 1 bath, office & fence.

"I enjoyed my stay and everything was as described. I would love to stay again if I’m in the area! "
The price is AED 367
AED 1,099 total
includes taxes & fees
1 Dec - 2 Dec
Downtown rambler. 2 bed, 1 bath, office & fence.
Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.
Exterior detail

Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.

10.0 out of 10, Exceptional, (57)
"One of the best VRBOs we have stayed in and for sure the cleanest. This home is lovely, decorated beautifully and supplied with everything we needed. We had several appointments at St. Mary’s Hospital and the Mayo/Gonda buildings. This home was conveniently located between the two and walkable to both.. Restaurants and grocery stores nearby and off-street parking. Hosts were very responsive and accommodating. We’ll stay here again."
Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.
Sunrise on Skyline - Indoor Pool - Arcades - Amazing Views!
You'll have endless fun in our endless pool! Overlooks the Mississippi River!

Sunrise on Skyline - Indoor Pool - Arcades - Amazing Views!

10.0 out of 10, Exceptional, (61)
"We love our whole experience. Home was very clean, check in was a breeze, and so much to do. The host was easy to communicate with. They had the most wonderful and thoughtful welcome basket. Highly recommend this home and we will definitely be back in the future."
Sunrise on Skyline - Indoor Pool - Arcades - Amazing Views!
Park in the Garage and Walk to Mayo Clinic
King size bed with memory foam mattress in primary bedroom located upstairs.

Park in the Garage and Walk to Mayo Clinic

10.0 out of 10, Exceptional, (51)
"We stayed during medical visits at Mayo and enjoyed being able to walk to the clinic, come back and relax in such a comfortable place. Excellent communication from Jill, the owner, "
Park in the Garage and Walk to Mayo Clinic
"Amazing Views" in Lake City, MN provides Coastal Charm!!
Terrace/patio

"Amazing Views" in Lake City, MN provides Coastal Charm!!

10.0 out of 10, Exceptional, (110)
"Beautifully decorated home with a great view of the mighty Mississippi! Comfortable accommodations and very clean!"
"Amazing Views" in Lake City, MN provides Coastal Charm!!
Cheerful cottage w/ fireplace. Great location for exploring the Lake Pepin area!
Living area

Cheerful cottage w/ fireplace. Great location for exploring the Lake Pepin area!

9.8 out of 10, Exceptional, (27)
"Very clean and comfortable!"
Cheerful cottage w/ fireplace. Great location for exploring the Lake Pepin area!
Elegant Home w/ Deck, 5 Blocks to Mayo Clinic
Rochester Vacation Rental | 3BR | 2BA | 2,084 Sq Ft | Step-Free Entry (Rear)

Elegant Home w/ Deck, 5 Blocks to Mayo Clinic

9.8 out of 10, Exceptional, (8)
"Convenient location to Mayo Clinic, comfortable, and well stocked for our week stay."
Elegant Home w/ Deck, 5 Blocks to Mayo Clinic
Luxury Stay/ Theater / Pool Table / Dogs Welcome
Living area

Luxury Stay/ Theater / Pool Table / Dogs Welcome

2.0 star property
Luxury Stay/ Theater / Pool Table / Dogs Welcome
"Walden Pond" Adventure Amidst 44 Private Acres
Enjoy the comfort and beauty of the inside and the awesome adventure outside.

"Walden Pond" Adventure Amidst 44 Private Acres

10.0 out of 10, Exceptional, (118)
"Really enjoyed the stay. It was very relaxing and a lot of fun"
"Walden Pond" Adventure Amidst 44 Private Acres
BIG Discount! Five Star-3 Bedroom Showstopper 4 Minutes to Mayo Clinic!
Relax in our stylishly decorated living room.

BIG Discount! Five Star-3 Bedroom Showstopper 4 Minutes to Mayo Clinic!

9.6 out of 10, Exceptional, (8)
"We enjoyed our stay and appreciated how easy it was to reserve and communicate with the host! Thank you so much!"
BIG Discount! Five Star-3 Bedroom Showstopper 4 Minutes to Mayo Clinic!
Luxury Cannon Lake Home w/ Private Pool & Views
Morristown Vacation Rental | 3BR | 2BA | Step-Free Entry | 2,000 Sq Ft

Luxury Cannon Lake Home w/ Private Pool & Views

8.6 out of 10, Excellent, (14)
"We came down to the area to do some daypasses at Kamp Dels 15 minutes away. Worked great to come back to after a day at the lake and have a big meal and relax. Just what we needed!"
Luxury Cannon Lake Home w/ Private Pool & Views
All Year Hot Tub, Dog Friendly, Fire Pit with Firewood and Washer & Dryer
Property grounds

All Year Hot Tub, Dog Friendly, Fire Pit with Firewood and Washer & Dryer

10.0 out of 10, Exceptional, (21)
"2 nights in Lake City were nice and cozy in this house! The beds were comfy, and the hot tub was enjoyed. There were a lot of nice little extras that I’ll save as surprises for when you book!"
The price is AED 676
AED 1,543 total
includes taxes & fees
1 Dec - 2 Dec
All Year Hot Tub, Dog Friendly, Fire Pit with Firewood and Washer & Dryer
Villa Serra - Lakehouse in Pepin
Porch chairs with lake views

Villa Serra - Lakehouse in Pepin

10.0 out of 10, Exceptional, (56)
"Loved the location and the views!"
Villa Serra - Lakehouse in Pepin
Fresh space near Mayo Clinic and downtown
Living room, which is open to the dining room

Fresh space near Mayo Clinic and downtown

9.6 out of 10, Exceptional, (16)
"Very clean property. It was comfortable and cute. The owners were responsive to us and so helpful"
Fresh space near Mayo Clinic and downtown
Charming Retreat w/ Deck - Walk to Lake Pepin
Pepin Vacation Rental | 4BR | 1BA | 1,700 Sq Ft | Steps Required

Charming Retreat w/ Deck - Walk to Lake Pepin

10.0 out of 10, Exceptional, (21)
"The house was comfortable and inviting!"
Charming Retreat w/ Deck - Walk to Lake Pepin
Delightful family home near pool, playground, park, nature center 1.6 mi to Mayo
Home Front

Delightful family home near pool, playground, park, nature center 1.6 mi to Mayo

10.0 out of 10, Exceptional, (23)
"A family member had several day appointments at the Mayo. He has mobility iaauws. Thia home eas perfect. 1 level. Walk-in shower. Bed with head and feet incline."
Delightful family home near pool, playground, park, nature center 1.6 mi to Mayo
2023 Construction, 5 BR, Gym, Game Area
Living room

2023 Construction, 5 BR, Gym, Game Area

10.0 out of 10, Exceptional, (14)
"AMAZING!!!! Every single thing about this property/ stay was far above and beyond our expectations. The house is amazing. The photos are totally accurate, but still don’t do it justice. We were in town for our dad’s 95th birthday. Our children/grandchildren live in 4 different states. All were able to come for the weekend and the house accommodated all of us, in every age category. Pamela went the “extra mile” in every aspect of this property from laundry pods to coffee to hair dryers to...
2023 Construction, 5 BR, Gym, Game Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in Southeast Minnesota

The Berkman
Lobby

The Berkman

3.0 star property
9.6 out of 10, Exceptional, (254)
"I come down here to stay at the Berkman because it’s close to the Mayo Clinic and it’s convenient for me. Any questions I have. They are so eager to help me. I feel very welcome there."
The price is AED 615
AED 715 total
includes taxes & fees
13 Dec - 14 Dec
The Berkman
Charming Cottage in Stockholm, WI Nations Best: Pies, Scenic Drive, Small Town!
Large Welcoming Shady Deck With Lake Breeze And Sunset Views

Charming Cottage in Stockholm, WI Nations Best: Pies, Scenic Drive, Small Town!

9.2 out of 10, Wonderful, (50)
"Very easy to access, nice location in the middle of the town. The outdoor sitting area was particularly nice. "
Charming Cottage in Stockholm, WI Nations Best: Pies, Scenic Drive, Small Town!
Broadway Plaza, Trademark Collection by Wyndham
Room

Broadway Plaza, Trademark Collection by Wyndham

3.0 star property
9.2 out of 10, Wonderful, (145)
"Great place to stay. Very handy for walking to the Mayo Clinic. Also very clean. Although we only stayed one night, it would be especially nice for longer stays as it really is a small apartment."
Broadway Plaza, Trademark Collection by Wyndham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.