Search Vacation Homes in Santa Clara

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check prices for these dates

Next weekend
In two weeks
In one month
In two months

Compare 68 Vacation Homes in Santa Clara with updated reviews, rates, and availability.

Oasis with pool near panama canal

9.6 out of 10, Exceptional, (14)
"Plenty of room to spread out. Well kept with all amenities.Will be back for sure."
The price is AED 698
AED 995 total
includes taxes & fees
28 Feb - 1 Mar
Oasis with pool near panama canal

3BR Home in Ancon Hill - Urban Oasis

3BR Home in Ancon Hill - Urban Oasis

Breathtaking Views Mansion w/King Beds

10.0 out of 10, Exceptional, (2)
"Great location, quiet neighborhood!"
The price is AED 1,928
AED 2,204 total
includes taxes & fees
4 Mar - 5 Mar
Breathtaking Views Mansion w/King Beds

Charming Maison 4Bdr + 4Bth in Historic Center of Casco Viejo

10.0 out of 10, Exceptional, (3)
"Everything about this location perfect "
The price is AED 1,350
AED 1,857 total
includes taxes & fees
4 Mar - 5 Mar
Charming Maison 4Bdr + 4Bth in Historic Center of Casco Viejo

Tropical House with Historic Charm, WiFi, Private Bathrooms and Workspaces

2.0 star property
The price is AED 1,836
AED 2,351 total
includes taxes & fees
4 Mar - 5 Mar
Tropical House with Historic Charm, WiFi, Private Bathrooms and Workspaces

Two Floors Duplex in the middle of Panama City.

9.2 out of 10, Wonderful, (7)
"We loved the residence, very well maintained, clean, everything at our fingertips. The owner was wonderful, he helped with so many things that made our stay very special.Very spacious, wonderful amenities, the pool area was used a lot, we sat, we swam and enjoyed playing cards in the evening, read a little as well.This home I would go back to when returning to Panama. Thank you so much for a wonderful stay and all that you helped us with in getting around the city."
Two Floors Duplex in the middle of Panama City.

Private Vacation Home: Pool, BBQ and more

6.6 out of 10, (4)
"The 6 of us enjoyed our stay. Good location and nice place"
Private Vacation Home: Pool, BBQ and more

Cozy 3-bedroom townhome with WiFi, AC in fabulous Panamá

10.0 out of 10, Exceptional, (1)
"The address was a bit confusing for the taxi drivers; they should mention that it is within the “Villas de Cantabria” gated area. You’ll have to call to be let in through the gate upon first arrival. Other than that, great place. It’s close to a train station and a supermarket."
Cozy 3-bedroom townhome with WiFi, AC in fabulous Panamá

Panama City economic room

The price is AED 129
AED 202 total
includes taxes & fees
28 Feb - 1 Mar
Panama City economic room

Bahia Breeze 3 BR Nature Sanctuary with pool in the Pearl Islands b

Bahia Breeze 3 BR Nature Sanctuary with pool in the Pearl Islands b

House in Punta Paitilla B19

10.0 out of 10, Exceptional, (5)
"The house is nicely appointed…very large. All bedrooms are good size. Multiple living areas. Great, clean pool. XL kitchen. The host, Jonathan, is extremely responsive. We had an issue with the ice machine (separate from the frig and freezer). He fixed within 20 minutes. The chef he recommended, Chef Alberto, was exceptional! He prepared 3 dinners for our family and it was so wonderful to just relax in the house after all day out in the heat. His son, Alberto, was helpful as an interpreter. Just...
The price is AED 2,570
AED 3,731 total
includes taxes & fees
6 Mar - 7 Mar
House in Punta Paitilla B19

Sunrise Ocean Views 19th Floor Gorgona Beach

Sunrise Ocean Views 19th Floor Gorgona Beach

King Beds 4br Urban Oasis w/ Coffee bar

The price is AED 918
AED 1,036 total
includes taxes & fees
3 Mar - 4 Mar
King Beds 4br Urban Oasis w/ Coffee bar

CASA ARANGO - A Charming Colonial House in the Heart of Casco Antiguo

10.0 out of 10, Exceptional, (1)
"Wonderful place , beautifully decorated, very clean, comfortable and fabulous location!!"
CASA ARANGO - A Charming Colonial House in the Heart of Casco Antiguo

Casa Ancon by Wynwood House

3.0 star property
10.0 out of 10, Exceptional, (1)
"Excelente para familias: una hermosa casa con un gran valor histórico de la época de la construcción del canal de Panamá. Aunque no hay acceso a toda la casa, los espacios eran amplios, acogedores y hermosamente decorados. Tener una cocina bien equipada y estar a 10 minutos de Albrook Mall en automóvil fue de mucha ayuda. Si no se cuenta con un vehículo propio puede ser un tanto complicado con el transporte."
Casa Ancon by Wynwood House

Complete house in Gamboa, by Panama Canal-Casa completa en Gamboa

7.6 out of 10, Good, (5)
"Beautiful area, house had potential but was poorly up-kept. Property owner spoke no English, making it hard to understand the rules and workings of the property such as the laundry room downstairs. Full of mold, making it tough to breathe. Screens are damaged or warped, so insects swarm the home at night. Amenities are nearly nonexistent, such as no trash bags, toilet paper, paper towels or coffee filters. Heavy metals made the water unsafe to drink, yet no good water was provided. Outside deck...
Complete house in Gamboa, by Panama Canal-Casa completa en Gamboa

Céntrica casa con bbq, piscina y seguridad 24/7

2.0 star property
The price is AED 551
AED 834 total
includes taxes & fees
8 Mar - 9 Mar
Céntrica casa con bbq, piscina y seguridad 24/7

Studio, 1 dbl Bed, with Kitchen, city view

8.4 out of 10, Very Good, (6)
"I enjoyed my stay. Very convenient and comfy."
The price is AED 294
AED 397 total
includes taxes & fees
28 Feb - 1 Mar
Studio, 1 dbl Bed, with Kitchen, city view

New Apt Great Hosts & Location

10.0 out of 10, Exceptional, (2)
"We loved staying here! Jorge and Mercedes were SO prompt in their responses, and attentive to any questions we had. The building is easy to negotiate, from parking, to pool, to apartment. Good location, Immaculately clean, reasonably priced. I can't say enough about how perfectly this place worked for us. Thank you for a wonderful visit to Panama City!!"
New Apt Great Hosts & Location

Modern apartment in Casa Azul, Casco Viejo

The price is AED 724
AED 1,017 total
includes taxes & fees
10 Mar - 11 Mar
Modern apartment in Casa Azul, Casco Viejo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Santa Clara
Save an average of 15% on thousands of hotels when you're signed in

Other property types in Santa Clara

Torres de Alba Hotel & Suites

3.5 star property
8.8 out of 10, Excellent, (429)
"Different elevators to get to different locations was confusing. I liked the cleanliness and amenities."
The price is AED 377
AED 415 total
includes taxes & fees
11 Mar - 12 Mar
Torres de Alba Hotel & Suites

Casco View Apartments

3.0 star property
9.4 out of 10, Exceptional, (19)
"It was a beautiful view of the ocean and the city from where I was. My friend unfortunately did not have as good of a view as me but I guess that's the luck of the draw. "
Casco View Apartments

Boutique Apartments Panama

3.5 star property
7.6 out of 10, Good, (60)
"Very nice place to stay. I will come back again "
The price is AED 162
AED 637 total
includes taxes & fees
30 Mar - 31 Mar
Boutique Apartments Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.