Photo by Corey Dargan

Find Luxury Hotels in Orangeburg, SC

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Check availability on Orangeburg Luxury Hotels

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Compare Orangeburg Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Travelodge by Wyndham Orangeburg

2.0 star property
8.2 out of 10, Very Good, (958)
"Hotel is very clean. Good for an overnight stay."
The price is AED 278
AED 308 total
includes taxes & fees
11 May - 12 May
Travelodge by Wyndham Orangeburg

Red Roof Inn Santee

2.0 star property
6.6 out of 10, (605)
"This was probably a nice place at one point in time but its in desperate need of a deep clean and remodel. Everything is outdated, dirty, and the breakfast was a joke"
The price is AED 246
AED 273 total
includes taxes & fees
1 Jun - 2 Jun
Red Roof Inn Santee

Comfort Inn & Suites Santee

2.5 star property
8.0 out of 10, Very Good, (981)
"Central location clean rooms, friendly staff."
The price is AED 403
AED 447 total
includes taxes & fees
14 May - 15 May
Comfort Inn & Suites Santee

Baymont by Wyndham Orangeburg North

2.5 star property
6.2 out of 10, (1001)
"Great room and comfortable bed, clean bathroom with working toilet ( I've stayed in placed where the commode won't flush). We will stay here again on our next trip through the area!"
The price is AED 279
AED 310 total
includes taxes & fees
12 May - 13 May
Baymont by Wyndham Orangeburg North

Baymont by Wyndham Santee

2.5 star property
8.0 out of 10, Very Good, (1291)
"Great staff comfy stay "
The price is AED 294
AED 326 total
includes taxes & fees
8 May - 9 May
Baymont by Wyndham Santee

Ramada by Wyndham Santee I-95

2.0 star property
6.2 out of 10, (521)
"The property needs some work but it was quiet and close to a few restaurants we could walk to."
The price is AED 286
AED 318 total
includes taxes & fees
19 May - 20 May
Ramada by Wyndham Santee I-95

Econo Lodge

2.0 star property
6.4 out of 10, (307)
"Check in was easy."
The price is AED 250
AED 277 total
includes taxes & fees
20 May - 21 May
Econo Lodge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are you searching for the perfect hotel for your luxury holiday in Orangeburg?
Use Expedia and let us help you arrange a flight to Columbia Metropolitan Airport (CAE) airport, and then select from different places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to find what you need to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Orangeburg offers. During your visit, you might want to enjoy the sporting events and university which Orangeburg is known for.
How many luxury hotels can I expect to find in Orangeburg?
Lie in the lap of luxury during your getaway to Orangeburg in one of Expedia’s 14 luxury hotels.
When can I expect good weather in Orangeburg?
Planning for the weather is a good way to make your trip to Orangeburg relaxing and enjoyable, especially when you’re splurging. The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 51°F. Average annual precipitation for Orangeburg is 52 inches.
What's there to see and do in Orangeburg?
Experience Orangeburg with a stop at South Carolina State College Historic District, Smith-Hammond-Middleton Memorial Center, and Edisto Memorial Gardens. If you have a little extra time during your trip, you might want to make a stop at Claflin University and South Carolina State University.