Photo by Corey Dargan

Find Luxury Hotels in Orangeburg, SC

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Check availability on Orangeburg Luxury Hotels

Compare Orangeburg Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Travelodge by Wyndham Orangeburg

2.0 star property
8.2 out of 10, Very Good, (938)
"Good, but the breakfast was very poor "
The price is AED 327
AED 363 total
includes taxes & fees
13 Apr - 14 Apr
Travelodge by Wyndham Orangeburg

Red Roof Inn Santee

2.0 star property
6.6 out of 10, (603)
"Comfortable , clean and friendly. Very convenient location."
The price is AED 257
AED 285 total
includes taxes & fees
13 Apr - 14 Apr
Red Roof Inn Santee

Comfort Inn & Suites Santee

2.5 star property
8.0 out of 10, Very Good, (970)
"Ok"
The price is AED 403
AED 447 total
includes taxes & fees
21 Apr - 22 Apr
Comfort Inn & Suites Santee

Baymont by Wyndham Orangeburg North

2.5 star property
6.4 out of 10, (1002)
"Breakfast could have been a little better"
The price is AED 283
AED 314 total
includes taxes & fees
13 Apr - 14 Apr
Baymont by Wyndham Orangeburg North

Baymont by Wyndham Santee

2.5 star property
8.0 out of 10, Very Good, (1298)
"We enjoyed our stay here. The room was modern and clean. Comfortable beds and amenities in bathroom. Wish there was a hot breakfast served but there is bagels and waffles. "
The price is AED 294
AED 326 total
includes taxes & fees
13 Apr - 14 Apr
Baymont by Wyndham Santee

Ramada by Wyndham Santee I-95

2.0 star property
6.2 out of 10, (519)
"Everyone that works here is very nice, including the owner. I feel safe and comfortable."
The price is AED 297
AED 329 total
includes taxes & fees
21 Apr - 22 Apr
Ramada by Wyndham Santee I-95

Econo Lodge

2.0 star property
6.4 out of 10, (307)
"Check in was easy."
The price is AED 216
AED 240 total
includes taxes & fees
11 May - 12 May
Econo Lodge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are you searching for the perfect hotel for your luxury holiday in Orangeburg?
Use Expedia and let us help you arrange a flight to Columbia Metropolitan Airport (CAE) airport, and then select from different places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to find what you need to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Orangeburg offers. During your visit, you might want to enjoy the sporting events and university which Orangeburg is known for.
How many luxury hotels can I expect to find in Orangeburg?
Lie in the lap of luxury during your getaway to Orangeburg in one of Expedia’s 14 luxury hotels.
When can I expect good weather in Orangeburg?
Planning for the weather is a good way to make your trip to Orangeburg relaxing and enjoyable, especially when you’re splurging. The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 51°F. Average annual precipitation for Orangeburg is 52 inches.
What's there to see and do in Orangeburg?
Experience Orangeburg with a stop at South Carolina State College Historic District, Smith-Hammond-Middleton Memorial Center, and Edisto Memorial Gardens. If you have a little extra time during your trip, you might want to make a stop at Claflin University and South Carolina State University.