Medical Center District Vacations

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Where to stay in Medical Center District

Find the best Medical Center District areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center District
Downtown - Riverwalk which includes heritage architecture, boating and a river or creek

Downtown San Antonio

3 out of top 10 points of interest in this area
4/5(9,525 area reviews)

Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.

Find hotels in Downtown San Antonio

Medical Center District Hotel Deals

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
2.5 out of 5
4431 Horizon Hill Blvd, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is AED 326 per night from Apr 8 to Apr 9
AED 326
AED 386 total
includes taxes & fees
8 Apr - 9 Apr
8.4/10 Very Good! (2,374 reviews)
"I was visiting family in the hospital, this was a very convenient location. Area is quiet and seems safe. Breakfast was minimal. No real conplaints other than the food"

Reviewed on 30 March 2025

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center
San Antonio Marriott Northwest Medical Center
3.5 out of 5
3233 NW Loop 410, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is AED 350 per night from Apr 17 to Apr 18
AED 350
AED 416 total
includes taxes & fees
17 Apr - 18 Apr
8.2/10 Very Good! (1,006 reviews)
"Amazing"

Reviewed on 30 March 2025

San Antonio Marriott Northwest Medical Center
Riverwalk Plaza
Riverwalk Plaza
4 out of 5
100 Villita Street, Dwyer/Main Plaza, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is AED 408 per night from Apr 15 to Apr 16
AED 408
AED 483 total
includes taxes & fees
15 Apr - 16 Apr
8/10 Very Good! (4,972 reviews)
"Conveniently located"

Reviewed on 30 March 2025

Riverwalk Plaza
See all 4,269 properties in Medical Center District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Medical Center District

River Walk featuring night scenes and a river or creek

River Walk

4.5/5(7,278 reviews)

River Walk is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Discover the fascinating museums and shops in this walkable area.

River Walk
Lackland Air Force Base

Lackland Air Force Base

4.5/5(1,254 reviews)

Lackland Air Force Base is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Discover the entertainment venues and shops in this walkable area.

Lackland Air Force Base
Six Flags Fiesta Texas

Six Flags Fiesta Texas

4.5/5(970 reviews)

Enjoy the rides and games at Six Flags Fiesta Texas and see why this is a favorite theme park in San Antonio. Experience the lively festivals and acclaimed theater scene in this family-friendly area.

Six Flags Fiesta Texas