Find hotels near Main Street Hyannis, Hyannis from AED 246
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Compare 3,548 hotels close to Main Street Hyannis with room rates, reviews, and availability. Most hotels are fully refundable.

Sea Street Inn
Sea Street Inn
10.0 out of 10, Exceptional, (39)
The price is AED 950
AED 1,088 total
includes taxes & fees
24 Apr - 25 Apr

Cape Cod Harbor House Inn
Cape Cod Harbor House Inn
9.2 out of 10, Wonderful, (245)
The price is AED 364
AED 416 total
includes taxes & fees
4 May - 5 May

The Cove At Yarmouth
The Cove At Yarmouth
9.2 out of 10, Wonderful, (232)
The price is AED 502
AED 575 total
includes taxes & fees
27 Apr - 28 Apr

Hampton Inn & Suites Cape Cod-West Yarmouth
Hampton Inn & Suites Cape Cod-West Yarmouth
9.0 out of 10, Wonderful, (1001)
The price is AED 465
AED 532 total
includes taxes & fees
4 May - 5 May

Hyannis Travel Inn
Hyannis Travel Inn
9.6 out of 10, Exceptional, (1001)
The price is AED 320
AED 366 total
includes taxes & fees
27 Apr - 28 Apr

Cape Cod Inn
Cape Cod Inn
8.8 out of 10, Excellent, (422)
The price is AED 327
AED 374 total
includes taxes & fees
24 Apr - 25 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Hotels near Other Hyannis Attractions
Hotels near Other Hyannis Attractions

John F. Kennedy Hyannis Museum
4.5/5(137 reviews)
You can spend an afternoon browsing the exhibits at John F. Kennedy Hyannis Museum during your trip to Hyannis. Wander the beautiful beaches and waterfront in this family-friendly area.
Recent reviews of Main Street Hyannis hotels
Recent reviews of Main Street Hyannis hotels

Margaritaville Resort Cape Cod
5/5 Excellent
"We loved our stay, it was perfect, supper clean and beautiful! "
A verified traveler from Middletown stayed at Margaritaville Resort Cape Cod
Posted 1 day ago
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Hotels near popular Hyannis Attractions
- Hotels near John F. Kennedy Hyannis Museum
- Hotels near Hyannis Harbor
- Hotels near Cape Cod Melody Tent
- Hotels near West Dennis Beach
- Hotels near Mayflower Beach
- Hotels near Cape Cod Inflatable Park
- Hotels near Craigville Beach
- Hotels near Sandy Neck Beach
- Hotels near Harwich Port
- Hotels near Seagull Beach
- Hotels near Kalmus Beach
- Hotels near Cape Cod Rail Trail
- Hotels near Mashpee Commons
- Hotels near Corporation Beach
- Hotels near Sea Street Beach
- Hotels near Cape Cod Baseball Hall of Fame
- Hotels near Barnstable Harbor
- Hotels near John F. Kennedy Memorial
- Hotels near Grays Beach
- Hotels near Breakwater Beach
Other Hotels near Main Street Hyannis, Hyannis
- Cape Cod Hotels
- Martha's Vineyard Hotels
- Hyannis Hotels
- Chatham Hotels
- Falmouth Hotels
- Plymouth Hotels
- East Sandwich Hotels
- Dennis Port Hotels
- Edgartown Hotels
- South Yarmouth Hotels
- Brewster Hotels
- West Yarmouth Hotels
- North Chatham Hotels
- Eastham Hotels
- Wellfleet Hotels
- Oak Bluffs Hotels
- Orleans Hotels
- East Falmouth Hotels
- Dennis Hotels
- Harwich Hotels
More Hotel Options in Main Street Hyannis
- Adventure Hotels
- Beach Hotels
- Business Hotels
- Cheap Hotels
- Family Hotels
- Golf Hotels
- Hotel Wedding Venues
- Hotel with a Concierge
- Hotels with Bars
- Hotels with Free Parking
- Hotels with Hot Tubs
- Hotels with Waterslides
- Hotels with WiFi
- Hotels with a Pool
- Hotels with an Indoor Pool
- Hotels with smoking rooms
- Resorts & Hotels with Spas
- Shopping Hotels
- Waterpark Hotels
- Winery Hotels
Explore more hotels
- Americas Best Value Inn & Suites Hyannis Cape Cod
- Cape Sands Inn
- Courtyard By Marriott Cape Cod Hyannis
- Doubletree by Hilton Cape Cod - Hyannis
- Heritage House Inn on Cape Cod
- Colonial Acres Resort
- Cape Cod Harbor House Inn
- Hyannis Plaza Hotel
- SPACIOUS HOME w/CENTRAL A/C & PRIVATE FENCED IN HALF ACRE YARD. WALK TO ALL..
- Waterfront 5-Bed 2-Bath Retreat
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