Find hotels near Main Street Hyannis, Hyannis from AED 246
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Compare 3,536 hotels close to Main Street Hyannis with room rates, reviews, and availability. Most hotels are fully refundable.

Hyannis Travel Inn
Hyannis Travel Inn
9.6 out of 10, Exceptional, (1053)
The price is AED 332
AED 380 total
includes taxes & fees
13 Apr - 14 Apr

Sea Street Inn
Sea Street Inn
10.0 out of 10, Exceptional, (39)
The price is AED 950
AED 1,088 total
includes taxes & fees
6 Apr - 7 Apr

Anchor In Distinctive Waterfront Lodging
Anchor In Distinctive Waterfront Lodging
9.4 out of 10, Exceptional, (1042)
The price is AED 559
AED 973 total
includes taxes & fees
22 Apr - 23 Apr

Hyannis Inn
Hyannis Inn
8.6 out of 10, Excellent, (983)
The price is AED 322
AED 369 total
includes taxes & fees
13 Apr - 14 Apr

Hampton Inn & Suites Cape Cod-West Yarmouth
Hampton Inn & Suites Cape Cod-West Yarmouth
9.0 out of 10, Wonderful, (1044)
The price is AED 465
AED 532 total
includes taxes & fees
8 Apr - 9 Apr

The Cove At Yarmouth
The Cove At Yarmouth
9.2 out of 10, Wonderful, (230)
The price is AED 502
AED 575 total
includes taxes & fees
3 Apr - 4 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Hotels near Other Hyannis Attractions
Hotels near Other Hyannis Attractions

John F. Kennedy Hyannis Museum
4.5/5(137 reviews)
You can spend an afternoon browsing the exhibits at John F. Kennedy Hyannis Museum during your trip to Hyannis. Wander the beautiful beaches and waterfront in this family-friendly area.
Recent reviews of Main Street Hyannis hotels
Recent reviews of Main Street Hyannis hotels

Hampton Inn & Suites Cape Cod-West Yarmouth
5/5 Excellent
"Liked the room and location. Friendly staff. "
A verified traveler stayed at Hampton Inn & Suites Cape Cod-West Yarmouth
Posted 2 days ago
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Hotels near popular Hyannis Attractions
- Hotels near John F. Kennedy Hyannis Museum
- Hotels near Hyannis Harbor
- Hotels near Cape Cod Melody Tent
- Hotels near Mayflower Beach
- Hotels near Cape Cod Inflatable Park
- Hotels near Harwich Port
- Hotels near West Dennis Beach
- Hotels near Craigville Beach
- Hotels near Sandy Neck Beach
- Hotels near Seagull Beach
- Hotels near Cape Cod Rail Trail
- Hotels near Mashpee Commons
- Hotels near Corporation Beach
- Hotels near Sea Street Beach
- Hotels near Kalmus Beach
- Hotels near Barnstable Harbor
- Hotels near John F. Kennedy Memorial
- Hotels near Cape Cod Baseball Hall of Fame
- Hotels near Grays Beach
- Hotels near Breakwater Beach
Other Hotels near Main Street Hyannis, Hyannis
- Cape Cod Hotels
- Martha's Vineyard Hotels
- Hyannis Hotels
- Chatham Hotels
- Plymouth Hotels
- Falmouth Hotels
- Dennis Port Hotels
- Edgartown Hotels
- South Yarmouth Hotels
- Brewster Hotels
- East Sandwich Hotels
- West Yarmouth Hotels
- Eastham Hotels
- Wellfleet Hotels
- Oak Bluffs Hotels
- North Chatham Hotels
- Orleans Hotels
- Dennis Hotels
- East Falmouth Hotels
- Harwich Hotels
More Hotel Options in Main Street Hyannis
- Adventure Hotels
- Beach Hotels
- Business Hotels
- Cheap Hotels
- Family Hotels
- Golf Hotels
- Hotel Wedding Venues
- Hotel with a Concierge
- Hotels with Bars
- Hotels with Free Parking
- Hotels with Hot Tubs
- Hotels with Waterslides
- Hotels with WiFi
- Hotels with a Pool
- Hotels with an Indoor Pool
- Hotels with smoking rooms
- Resorts & Hotels with Spas
- Shopping Hotels
- Waterpark Hotels
- Winery Hotels
Explore more hotels
- Courtyard Resort
- Americas Best Value Inn & Suites Hyannis Cape Cod
- Courtyard By Marriott Cape Cod Hyannis
- Colonial Acres Resort
- Doubletree by Hilton Cape Cod - Hyannis
- Hyannis Plaza Hotel
- Cape Sands Inn
- SPACIOUS HOME w/CENTRAL A/C & PRIVATE FENCED IN HALF ACRE YARD. WALK TO ALL..
- Waterfront 5-Bed 2-Bath Retreat
- Cape Cod Irish Village
- Walk to Beach & Main Street: Hyannis Cottage
- MINS TO BEACHES WALK TO DOWNTOWN, HARBOR & SHOPS NICE FENCED YARD - A/C & WiFi