Photo by Jackie Rodriguez

Find Luxury Hotels in Hartsville, SC

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Compare Hartsville Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

The Mantissa Hotel

3.0 star property
9.2 out of 10, Wonderful, (214)
"Great rooms."
The price is AED 625
AED 700 total
includes taxes & fees
5 Jan - 6 January 2025
The Mantissa Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in Hartsville?
Expedia can help you arrange a flight to Florence, SC (FLO-Florence Regional) airport, and then you can select from various places to stay that will deliver the luxury you’d like to find. Amenities are important when you plan a trip, so we make it easy to find what you’d like to make your stay special. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Hartsville offers. During your visit, you might want to enjoy the walking which Hartsville is known for.
When can I expect good weather in Hartsville?
Planning for the weather is an important factor for making your trip to Hartsville a success, especially when you’re splurging. The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 49°F. Average annual precipitation for Hartsville is 52 inches.
What's there to see and do in Hartsville?
Take in the sights and attractions that Hartsville offers with a visit to Hartsville Museum, East Home Avenue Historic District, and Neptune Island Waterpark. If you have a little extra time during your trip, you might want to check out Hartsville City Hall and Center Theatre.