Photo by Jackie Rodriguez
Find Business Hotels in Hartsville, SC
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check availability on Hartsville Business Hotels
Compare Hartsville Business Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Fairfield Inn by Marriott Hartsville
Fairfield Inn by Marriott Hartsville
8.6 out of 10, Excellent, (623)
The price is AED 377
AED 422 total
includes taxes & fees
18 May - 19 May

Hampton Inn & Suites Hartsville
Hampton Inn & Suites Hartsville
9.2 out of 10, Wonderful, (442)
The price is AED 465
AED 521 total
includes taxes & fees
26 May - 27 May

The Landmark Inn
The Landmark Inn
7.0 out of 10, Good, (282)
The price is AED 248
AED 291 total
includes taxes & fees
8 May - 9 May

The Mantissa Hotel
The Mantissa Hotel
9.2 out of 10, Wonderful, (233)
The price is AED 625
AED 700 total
includes taxes & fees
21 May - 22 May

Quality Inn
Quality Inn
6.0 out of 10, (281)
The price is AED 214
AED 240 total
includes taxes & fees
21 May - 22 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find out more about Hartsville
Find out more about Hartsville
Recent reviews of Hartsville hotels
Recent reviews of Hartsville hotels

La Quinta Inn & Suites by Wyndham Florence
5/5 Excellent
"Somewhat outdated, but convenient. Staff was great, checkin and checkout. Breakfast was good"
A verified traveler stayed at La Quinta Inn & Suites by Wyndham Florence
Posted 2 days ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Find More Hotels near Hartsville
More Hotel Options in Hartsville
- Adventure Hotels in Hartsville
- Beach Hotels in Hartsville
- Boutique Hotels in Hartsville
- Family Hotels in Hartsville
- Hotel Wedding Venues in Hartsville
- Hotel with a Concierge in Hartsville
- Hotels with Bars in Hartsville
- Hotels with Free Parking in Hartsville
- Hotels with WiFi in Hartsville
- Hotels with a Pool in Hartsville
- Luxury Hotels in Hartsville
- Pet-friendly Hotels in Hartsville
- Resorts & Hotels with Spas in Hartsville
- Shopping Hotels in Hartsville
More Accommodation Types in
- Condo Rentals in South Carolina
- Vacation Homes in South Carolina
- Apartments in South Carolina
- Villas in South Carolina
- Resorts in South Carolina
- Cottages in South Carolina
- Cabin Rentals in South Carolina
- Aparthotels in South Carolina
- Motels in South Carolina
- Guest Houses in South Carolina
- B&B in South Carolina
- Lodges in South Carolina
- Condo Resorts in South Carolina
- Houseboats in South Carolina
- Inns in South Carolina
- Country Houses in South Carolina
- Hostels in South Carolina
Hartsville Hotels by Star Rating
Explore more hotels
- Quality Inn & Suites Florence Civic Center
- Comfort Inn & Suites
- Hyatt Place Florence Downtown
- Days Inn by Wyndham Florence/I-95 North
- La Quinta Inn & Suites by Wyndham Florence
- Days Inn by Wyndham Florence Near Civic Center
- Microtel Inn & Suites by Wyndham Florence
- Sleep Inn Florence North
- Hampton Inn & Suites Florence Center
- Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
- Hampton Inn & Suites Florence-North-I-95
- Aloft Florence
- Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
- Comfort Suites Florence I-95
- Red Roof Inn Florence - Civic Center
- Home2 Suites by Hilton Florence, SC
- Tru by Hilton Florence I-95
- Country Inn & Suites by Radisson, Florence, SC
- Courtyard by Marriott Florence
- TownePlace Suites by Marriott Florence