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Compare 73 Vacation Homes in De Soto with updated reviews, rates, and availability.

Newly remodeled cozy retreat. Pet friendly & 3 minute walk to the river!

10.0 out of 10, Exceptional, (29)
"Everything was very nice! We will be back. "
The price is AED 349
AED 446 total
includes taxes & fees
25 Dec - 26 Dec
Newly remodeled cozy retreat. Pet friendly & 3 minute walk to the river!

This big old charming house Viroqua

10.0 out of 10, Exceptional, (18)
"We headed to this area for a pilgrimage to the Shrine in LaCrosse. While the house may not be in the most picturesque location, it did not take anything away from such a great experience staying there. The house is big, clean, charming and full of character. The host did not hold back on the kitchenware, appliances, or furnishings. It has everything one needs. We had a great time, felt at home, and recommend this house to anyone staying in the area. "
This big old charming house Viroqua

Secluded Home - Views of Mississippi River remote location 15 min from La Crosse

10.0 out of 10, Exceptional, (148)
"This is our 3rd time staying here. It's a great spot to come down to see our grown kid and have everyone around. Enough to do in the house to not get bored if the weather is bad. Will be back as always. "
Secluded Home - Views of Mississippi River remote location 15 min from La Crosse

Wisconsin's Driftless Region Retreat

9.6 out of 10, Exceptional, (65)
"Wonderful again Thank you "
Wisconsin's Driftless Region Retreat

Secluded, Romantic, Family Friendly And Cozy, Last House In The Valley.

10.0 out of 10, Exceptional, (381)
"Good location, clean and dog friendly and suitable for a large family. "
Secluded, Romantic, Family Friendly And Cozy, Last House In The Valley.

Riverfront Twin Home

10.0 out of 10, Exceptional, (18)
"The place was very clean and conveniently located to downtown. "
The price is AED 551
AED 1,208 total
includes taxes & fees
24 Dec - 25 Dec
Riverfront Twin Home

3-bedroom country home in the driftless.

3-bedroom country home in the driftless.

Tiny House on Upper Iowa River w/ hot tub

8.8 out of 10, Excellent, (30)
"We had a great night away in the tiny house. A couple of tight fits if you’re over 6 feet tall, but if you don’t see that coming with a tiny home, well, that’s on you. Great experience! "
The price is AED 459
AED 893 total
includes taxes & fees
24 Dec - 25 Dec
Tiny House on Upper Iowa River w/ hot tub

Premium 3BR 3BA with Hot Tub & Pool, near all of LaCrosse's Top Rated Activities

9.8 out of 10, Exceptional, (27)
"This was a great vacation. It was very close to town and there was a ton of things to do around the area. We had a nice time around the pool and the hot tub was great way to unwind at the end of the day to. The owners were always quick to respond if we had any questions about the house. I would definitely recommend staying here."
Premium 3BR 3BA with Hot Tub & Pool, near all of LaCrosse's Top Rated Activities

Hot Tub! Cowboy Retreat! SW Wisconsin Driftless Region on UTV Route

9.2 out of 10, Wonderful, (20)
"My husband and I had a great weekend. We wish we could stayed longer! Ed was so nice and accommodating."
Hot Tub! Cowboy Retreat! SW Wisconsin Driftless Region on UTV Route

Secluded Rustic Cabin

9.8 out of 10, Exceptional, (40)
"Very nicely secluded. Would stay again."
The price is AED 962
AED 1,662 total
includes taxes & fees
7 Jan - 8 January 2025
Secluded Rustic Cabin

Nice Cape Cod home near the Mississippi River (Scenic River Inn)

9.8 out of 10, Exceptional, (119)
"Nice place would book again"
Nice Cape Cod home near the Mississippi River (Scenic River Inn)

Up The Creek Cottage - Townhome In Coon Valley

9.2 out of 10, Wonderful, (32)
"This property is very comfortable. And next door to the Stagecoach!"
Up The Creek Cottage - Townhome In Coon Valley

'RiverSong' Waterfront La Crosse Home w/ Dock

10.0 out of 10, Exceptional, (74)
"Beautiful home with amazing amenities! The owners were so friendly and accommodating. My family had a wonderful time here while visiting our son at UW La Crosse. "
'RiverSong' Waterfront La Crosse Home w/ Dock

Eagles Landing Sleeps 15 HOT TUB

10.0 out of 10, Exceptional, (13)
"We will definitely be back!"
Eagles Landing Sleeps 15 HOT TUB

Spacious Stoddard Retreat on Mississippi River!

10.0 out of 10, Exceptional, (12)
"House is as described in a beautiful location. Owners were wonderful and communication was very simple. "
Spacious Stoddard Retreat on Mississippi River!

Country Charm Over River Valley And Horse Farm

10.0 out of 10, Exceptional, (34)
"This place is beautiful - home as well as surrounding countryside. We had lovely views and places to walk. The house was clean, comfortable and well equipped… and the hosts were attentive and pleasantly communicative. Addressed any questions we had. We couldn’t have asked for a better place and highly recommend it! "
Country Charm Over River Valley And Horse Farm

Room on the Ridge / HOT TUB / Sleeps 2

The price is AED 441
AED 776 total
includes taxes & fees
5 Jan - 6 January 2025
Room on the Ridge / HOT TUB / Sleeps 2

A-frame home on Trout Stream

10.0 out of 10, Exceptional, (2)
"We met in La Crosse with our adult children and their families for Thanksgiving. We were so happy to have Dan's A Frame had availability!! He was excellent at communication, his entire home was clean and inviting! Sometime A Frames can be cold, but this home was toasty warm and even the 2 year old stayed warm all night!! Plenty of dishes, and cooking utensils to do a full Thanksgiving dinner!! We hope to come back in the summer and do some trout fishing!!! We will be back!"
A-frame home on Trout Stream

Cozy and charming. Your home away from home in the heart of Viroqua.

9.8 out of 10, Exceptional, (9)
"It was really nice to stay at the little yellow house and relax after being out, hunting in the cold the entire day. The host is extremely responsive, friendly, and accommodating. We would love to stay again in the future if available."
Cozy and charming. Your home away from home in the heart of Viroqua.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in De Soto

Rustic Hideaway Sleeps 4 HOT TUB

10.0 out of 10, Exceptional, (18)
"The cabin was perfect for our family. The kids had plenty of room in the loft. The kitchen was perfect for cooking a Thanksgiving meal. The hot tub was clean and ready to use when we arrived. The views were amazing and my kids loved the area so much they want to go back again. The owner was responsive and answered all of our questions before and during our stay. I highly recommend this property!"
The price is AED 716
AED 1,370 total
includes taxes & fees
5 Jan - 6 January 2025
Rustic Hideaway Sleeps 4 HOT TUB

Cozy Sportsman's Hideaway

9.0 out of 10, Wonderful, (9)
"Very nice host, Mike. Place was very clean & great furnishings and decor. Outdoor fire ring was a hit for us. Quiet area, hardly any traffic. Wished the property had more sunshine, but we weren't there much during the day anyway. was very clean, nice decor. Great to have waher and dryer+"
Cozy Sportsman's Hideaway

Paradise Point- Sleeps 4 HOT TUB

10.0 out of 10, Exceptional, (32)
"Nice and cozy. The views were amazing."
The price is AED 716
AED 1,280 total
includes taxes & fees
5 Jan - 6 January 2025
Paradise Point- Sleeps 4 HOT TUB
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.