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Compare 72 Vacation Homes in De Soto with updated reviews, rates, and availability.

This big old charming house Viroqua

10.0 out of 10, Exceptional, (21)
"This house was perfect for hosting my family. We had a wonderful time!"
This big old charming house Viroqua

Mississippi waterfront vacation home that welcomes dogs! Private dock for boats

2.0 star property
10.0 out of 10, Exceptional, (2)
"This is a beautiful home with an amazing river view! We loved the sunroom and the loft sitting area. The entire home is extremely clean and had everything we needed for cooking and playing games…2 large tables and even a drawer full of games. We brought our own games, but ended up putting those aside once our girls found that drawer. Communication with Shawna was very prompt. We will definitely stay here again if we’re back in the area!"
Mississippi waterfront vacation home that welcomes dogs! Private dock for boats

Secluded, Romantic, Family Friendly And Cozy, Last House In The Valley.

10.0 out of 10, Exceptional, (384)
"Beautiful location, owners are so friendly. "
Secluded, Romantic, Family Friendly And Cozy, Last House In The Valley.

Indoor Fish Cleaning - Arcade - Darts - Poker - Newly Remodeled

10.0 out of 10, Exceptional, (1)
"Good "
Indoor Fish Cleaning - Arcade - Darts - Poker - Newly Remodeled

Secluded Home - Views of Mississippi River remote location 15 min from La Crosse

10.0 out of 10, Exceptional, (148)
"This is our 3rd time staying here. It's a great spot to come down to see our grown kid and have everyone around. Enough to do in the house to not get bored if the weather is bad. Will be back as always. "
Secluded Home - Views of Mississippi River remote location 15 min from La Crosse

Spacious Stoddard Retreat on Mississippi River!

10.0 out of 10, Exceptional, (12)
"House is as described in a beautiful location. Owners were wonderful and communication was very simple. "
Spacious Stoddard Retreat on Mississippi River!

Large Secluded Country Home Minutes from Town

10.0 out of 10, Exceptional, (63)
"Lots of room and bery clean. Good views"
Large Secluded Country Home Minutes from Town

Hydro-Massage Tub! Wrangler Outlaw Suite! Horses!

9.6 out of 10, Exceptional, (55)
"Wonderful location, beautiful bathroom, relaxing. Definitely would visit again. "
The price is AED 364
AED 655 total
includes taxes & fees
26 Jan - 27 Jan
Hydro-Massage Tub! Wrangler Outlaw Suite! Horses!

Tiny House on Upper Iowa River w/ hot tub

8.6 out of 10, Excellent, (31)
"We had a great night away in the tiny house. A couple of tight fits if you’re over 6 feet tall, but if you don’t see that coming with a tiny home, well, that’s on you. Great experience! "
The price is AED 459
AED 880 total
includes taxes & fees
26 Jan - 27 Jan
Tiny House on Upper Iowa River w/ hot tub

Hot Tub! Cowboy Retreat! SW Wisconsin Driftless Region on UTV Route

9.2 out of 10, Wonderful, (21)
"Our family wanted to find a place to get together on the one year anniversary of the death of my wife to be by ourselves and share some memories. This place looked ideal when I looked it up on VRBO. It was every bit as good as we thought that it would be and more.The space is very large, even larger than it looks in the photographs. It takes up almost the entire downstairs area of a very large house. Even though we had seven members in our group, it didn't seem like we were right on top of each...
Hot Tub! Cowboy Retreat! SW Wisconsin Driftless Region on UTV Route

2-bedroom vacation home just 10 minutes from Viroqua's charming downtown

10.0 out of 10, Exceptional, (54)
"We enjoyed our time at this property. Rather small seating area in the living room but it was fine for the 3 of us. Nice sleeping area on the second floor. You get the feeling of being in the woodsey outdoors but just a quick 2 mile drive into town. "
2-bedroom vacation home just 10 minutes from Viroqua's charming downtown

Secluded Rustic Cabin

9.8 out of 10, Exceptional, (42)
"Cozy cabin on an absolutely beautiful secluded property. We enjoyed the hot tub, the fire pit and all the nature around us. Mt. LaCrosse ski area is about 25 minutes away where we spent 2 days skiing. "
The price is AED 1,010
AED 1,728 total
includes taxes & fees
26 Jan - 27 Jan
Secluded Rustic Cabin

Nice Cape Cod home near the Mississippi River (Scenic River Inn)

9.8 out of 10, Exceptional, (121)
"This was our second winter trip here. It's a great location for us to experience winter in the Driftless area"
Nice Cape Cod home near the Mississippi River (Scenic River Inn)

The Honey Haven

10.0 out of 10, Exceptional, (30)
"This is a great place to stay.Quiet and remote. If you’re staying here in the winter you will appreciate the heated floor in the main room. We were greeted by their dog Boone on arrival, who showed remarkable hospitality! Overall we felt like we were at home."
The price is AED 588
AED 930 total
includes taxes & fees
24 Jan - 25 Jan
The Honey Haven

Hygge Hideaway. Pet friendly, cozy retreat & 3 minute walk to the river!

10.0 out of 10, Exceptional, (33)
"This is a great spot for a weekend getaway! It has a cozy little cabin feel to it! It was very clean and easy to access. The hosts are wonderful and make it easy to check in and out! The neighborhood is quiet and quaint! We absolutely loved it and would definitely stay here again and recommend it to friends!"
The price is AED 386
AED 484 total
includes taxes & fees
24 Jan - 25 Jan
Hygge Hideaway. Pet friendly, cozy retreat & 3 minute walk to the river!

'RiverSong' Waterfront La Crosse Home w/ Dock

10.0 out of 10, Exceptional, (74)
"Beautiful home with amazing amenities! The owners were so friendly and accommodating. My family had a wonderful time here while visiting our son at UW La Crosse. "
'RiverSong' Waterfront La Crosse Home w/ Dock

Eagles Landing Sleeps 15 HOT TUB

10.0 out of 10, Exceptional, (13)
"We will definitely be back!"
Eagles Landing Sleeps 15 HOT TUB

Wisconsin's Driftless Region Retreat

9.6 out of 10, Exceptional, (65)
"Wonderful again Thank you "
Wisconsin's Driftless Region Retreat

Drop Tine Ridge w/Hot Tub

Drop Tine Ridge w/Hot Tub

A-frame home on Trout Stream

10.0 out of 10, Exceptional, (2)
"We met in La Crosse with our adult children and their families for Thanksgiving. We were so happy to have Dan's A Frame had availability!! He was excellent at communication, his entire home was clean and inviting! Sometime A Frames can be cold, but this home was toasty warm and even the 2 year old stayed warm all night!! Plenty of dishes, and cooking utensils to do a full Thanksgiving dinner!! We hope to come back in the summer and do some trout fishing!!! We will be back!"
A-frame home on Trout Stream
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in De Soto

Paradise Point- Sleeps 4 HOT TUB

10.0 out of 10, Exceptional, (33)
"Nice and cozy. The views were amazing."
The price is AED 716
AED 1,280 total
includes taxes & fees
28 Jan - 29 Jan
Paradise Point- Sleeps 4 HOT TUB

Romantic Log Cabin Hideaway, Hot tub nestled Near the Scenic Mississippi River!

9.8 out of 10, Exceptional, (97)
"We had a great, relaxing time here. Cabin was clean and as advertised, communication for check in/out was easy, and we loved the hot tub. Would definitely return in the future"
Romantic Log Cabin Hideaway, Hot tub nestled Near the Scenic Mississippi River!

Rustic Hideaway Sleeps 4 HOT TUB

10.0 out of 10, Exceptional, (20)
"The house was a great retreat to start the new year! We really enjoyed the hot tub. "
The price is AED 716
AED 1,371 total
includes taxes & fees
2 Feb - 3 Feb
Rustic Hideaway Sleeps 4 HOT TUB
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.