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Check prices for these dates

Next weekend
23 May - 25 May
In two weeks
30 May - 1 Jun
In one month
13 Jun - 15 Jun
In two months
11 Jul - 13 Jul

Compare 158 Vacation Homes in Byron with updated reviews, rates, and availability.

Century Cottage-PERFECT for Mayo & downtown visitors!
Outdoor dining

Century Cottage-PERFECT for Mayo & downtown visitors!

10.0 out of 10, Exceptional, (114)
"Easy access to Mayo and the host was fantastic "
Century Cottage-PERFECT for Mayo & downtown visitors!
Delightful family home near parks, nature center, 1.5 m to Mayo Clinic downtown
Miscellaneous

Delightful family home near parks, nature center, 1.5 m to Mayo Clinic downtown

10.0 out of 10, Exceptional, (41)
"Would stay again! Thank you!"
Delightful family home near parks, nature center, 1.5 m to Mayo Clinic downtown
1 mi. from Mayo Clinic; Cozy, Clean
Fridge, microwave, oven, stovetop

1 mi. from Mayo Clinic; Cozy, Clean

9.6 out of 10, Exceptional, (90)
"Whitney and Aaron are great hosts very responsive to any questions or concerns you might have. Based on our conversations I wish I could rate them 6 star hosts "
1 mi. from Mayo Clinic; Cozy, Clean
Entertainment for the whole family. Sleeps up to 10.
Fridge, microwave, oven, stovetop

Entertainment for the whole family. Sleeps up to 10.

10.0 out of 10, Exceptional, (3)
"The house was very clean, with everything you needed. I loved the cinema and the communication with the owner, who was excellent, very friendly. I sincerely recommend it. The area was very quiet."
Entertainment for the whole family. Sleeps up to 10.
Park-Side, Easy Access To Downtown, Mayo Clinic & Bike Trail, Family-Friendly
Fridge, microwave, oven, stovetop

Park-Side, Easy Access To Downtown, Mayo Clinic & Bike Trail, Family-Friendly

9.8 out of 10, Exceptional, (59)
"Everything about this Vrbo was excellent. My family raved about the lay-out, location and access to everything. It really felt like we were returning home everytime we pulled in. "
Park-Side, Easy Access To Downtown, Mayo Clinic & Bike Trail, Family-Friendly
Fresh space near Mayo Clinic and downtown
Microwave, dishwasher, coffee/tea maker, cookware/dishes/utensils

Fresh space near Mayo Clinic and downtown

9.4 out of 10, Exceptional, (19)
"Very clean property. It was comfortable and cute. The owners were responsive to us and so helpful"
Fresh space near Mayo Clinic and downtown
Magical Nest Hideaway
Exterior

Magical Nest Hideaway

10.0 out of 10, Exceptional, (114)
"The wild turkeys and deer who greeted us in the morning. "
Magical Nest Hideaway
Luxury Stay/ Theater / Pool Table / Dogs Welcome
Fridge, microwave, stovetop, coffee/tea maker

Luxury Stay/ Theater / Pool Table / Dogs Welcome

2.0 star property
10.0 out of 10, Exceptional, (9)
"Great place"
Luxury Stay/ Theater / Pool Table / Dogs Welcome
2 Bedroom Apartment, Walk To Mayo, Free Parking
TV, offices

2 Bedroom Apartment, Walk To Mayo, Free Parking

2.0 star property
10.0 out of 10, Exceptional, (1)
"My husband was being seen at Mayo Clinic this past week. This place is walking distance (if you are able) to walk to and from the main hospital (Mayo & Gonda). It made our stay easier knowing how close our place was. The staff was really quick to respond if/when we had questions or needed something. Will be staying here again! "
2 Bedroom Apartment, Walk To Mayo, Free Parking
Warm and cozy property<br>2 miles to Mayo and St. Mary’s. 4 bedrooms, 3 bathrooms.<br>
Outdoor dining

Warm and cozy property<br>2 miles to Mayo and St. Mary’s. 4 bedrooms, 3 bathrooms.<br>

10.0 out of 10, Exceptional, (23)
"Everything was very comfortable. "
Warm and cozy property<br>2 miles to Mayo and St. Mary’s. 4 bedrooms, 3 bathrooms.<br>
The Little House // Stylish & Cozy ~ 2 mi from Mayo Clinic
Terrace/patio

The Little House // Stylish & Cozy ~ 2 mi from Mayo Clinic

10.0 out of 10, Exceptional, (11)
"Very nice BnB! It's very cozy and welcoming..location is great! Will definitely be staying here again. Highly recommend this place!"
The Little House // Stylish & Cozy ~ 2 mi from Mayo Clinic
Charming 2-Bedroom house along city trail 1 mile from Mayo Clinic and downtown.
Property grounds

Charming 2-Bedroom house along city trail 1 mile from Mayo Clinic and downtown.

9.8 out of 10, Exceptional, (43)
"Quaint and very well supplied with anything we needed. Great location near Mayo, restaurants and shopping. Definitely would recommend this place."
Charming 2-Bedroom house along city trail 1 mile from Mayo Clinic and downtown.
"Walden Pond" Adventure Amidst 44 Private Acres
Interior

"Walden Pond" Adventure Amidst 44 Private Acres

10.0 out of 10, Exceptional, (124)
"It was a perfect location and a very relaxing visit!"
"Walden Pond" Adventure Amidst 44 Private Acres
Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.
Fridge, microwave, oven, stovetop

Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.

10.0 out of 10, Exceptional, (80)
"Wonderful house and location. "
Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.
Newly remodeled "Beach" Themed home that is close to downtown and Mayo Clinic.
Fridge, microwave, oven, stovetop

Newly remodeled "Beach" Themed home that is close to downtown and Mayo Clinic.

10.0 out of 10, Exceptional, (7)
"What an amazing property! This little home was perfect! I highly recommend anyone to rent this little home! "
Newly remodeled "Beach" Themed home that is close to downtown and Mayo Clinic.
☆Dee Dee's Den: A Dharma Dwellings Parent Company☆
Fridge, microwave, oven, stovetop

☆Dee Dee's Den: A Dharma Dwellings Parent Company☆

10.0 out of 10, Exceptional, (32)
"Great space for full family "
☆Dee Dee's Den: A Dharma Dwellings Parent Company☆
Historic City Hall Recorder's Office - ADA Accessible
Interior

Historic City Hall Recorder's Office - ADA Accessible

2.0 star property
10.0 out of 10, Exceptional, (7)
"The stay was awesome and the place was so clean! Would definitely recommend! "
Historic City Hall Recorder's Office - ADA Accessible
Silver Lake Oasis
Miscellaneous

Silver Lake Oasis

9.6 out of 10, Exceptional, (35)
"A nice little place, well kept and just as advertised."
Silver Lake Oasis
Discounted Charming 2-bedroom house in Rochester
Microwave, oven, stovetop, dishwasher

Discounted Charming 2-bedroom house in Rochester

10.0 out of 10, Exceptional, (1)
"Needed a last minute place to stay with my elderly parents for Mayo appointments. The home was clean, cute, location great, easy to find--very homey."
The price is AED 331
AED 803 total
includes taxes & fees
16 Jun - 17 Jun
Discounted Charming 2-bedroom house in Rochester
Charming 2 Bed 1 Bath Home W/Fully Fenced in Back yard
Outdoor dining

Charming 2 Bed 1 Bath Home W/Fully Fenced in Back yard

9.4 out of 10, Exceptional, (16)
"Everything was excellent! Super happy"
The price is AED 514
AED 1,235 total
includes taxes & fees
25 May - 26 May
Charming 2 Bed 1 Bath Home W/Fully Fenced in Back yard
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in Byron

The Berkman
Terrace/patio

The Berkman

3.0 star property
9.6 out of 10, Exceptional, (292)
"Great staff at check in "
The price is AED 393
AED 457 total
includes taxes & fees
31 May - 1 Jun
The Berkman
Broadway Plaza, Trademark Collection by Wyndham
Fridge, microwave, oven, stovetop

Broadway Plaza, Trademark Collection by Wyndham

3.0 star property
9.2 out of 10, Wonderful, (151)
"One bedroom suite, complete with washer/dryer. Very quiet. Not a real hotel. More a rental that lots of amenities. But perfect for my needs."
Broadway Plaza, Trademark Collection by Wyndham
Charming 2-Bedroom house along city trail 1 mile from Mayo Clinic and downtown.
Property grounds

Charming 2-Bedroom house along city trail 1 mile from Mayo Clinic and downtown.

9.8 out of 10, Exceptional, (43)
"Quaint and very well supplied with anything we needed. Great location near Mayo, restaurants and shopping. Definitely would recommend this place."
Charming 2-Bedroom house along city trail 1 mile from Mayo Clinic and downtown.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.