Find All Southeast Missouri Hotels
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Find All Southeast Missouri Hotels
We have found 539 Southeast Missouri Hotels
- SOLAR ECLIPSE! Lodge on10ac open field. 4 bed, 1 bath. Family/Pet friendly
- Alpaca Farm Stay
- The Woods and Willow Room. 2 queen beds and grab-n-go breakfast items
- Arcadia Academy
- Sam A Baker
- Eagle's Landing River Resort
- Fairfield by Marriott Inn & Suites Sikeston
- TownePlace Suites by Marriott Sikeston
- Old Caledonian Bed and Breakfast
- Charming 1-bedroom B&B with AC, WiFi in historic Cape Girardeau
- River City Casino & Hotel
- The Wildwood Hotel
- Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
- Wingate by Wyndham St. Louis/Fenton Route 66
- Forest Park Hotel by MDR
- Best Western St. Louis-Kirkwood Route 66
- La Quinta Inn & Suites by Wyndham St Louis Route 66
- Drury Inn & Suites St. Louis Brentwood
- Best Western St. Louis Inn
- Holiday Inn Express & Suites St. Louis South - I-55, an IHG Hotel
- Drury Inn & Suites St. Louis Forest Park
- SpringHill Suites St. Louis Brentwood
- Aviator Hotel & Suites South I-55, BW Signature Collection
- Hilton St. Louis Frontenac
- Drury Inn & Suites Southwest St. Louis
- TownePlace Suites by Marriott Brentwood
- Best Western Plus Fenton
- Holiday Inn St. Louis West Six Flags, an IHG Hotel
- Hampton Inn Blytheville
- Holiday Inn Express & Suites St. Louis West - Fenton, an IHG Hotel
- Pinemark Inn & Suites
- Holiday Inn St Louis SW - Route 66, an IHG Hotel
- Pear Tree Inn St. Louis Arnold
- Extended Stay America Suites - St Louis - Fenton
- Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave
- Baymont by Wyndham West Plains
- Holiday Inn Blytheville, an IHG Hotel
- Holiday Inn Express & Suites Murphysboro - Carbondale, an IHG Hotel
- Americas Best Value Inn St. Louis South
- Comfort Inn Sullivan
- Drury Inn & Suites St. Louis Arnold
- Comfort Inn Near Six Flags St. Louis
- Quality Inn & Suites near St. Louis and I-255
- Residence Inn by Marriott St. Louis West County
- Hampton Inn & Suites St. Louis/South I-55
- The Lodge at Grant's Trail
- Baymont by Wyndham Sullivan
- Fairfield Inn & Suites by Marriott St. Louis South
- Comfort Inn & Suites
- Courtyard by Marriott St. Louis West County
- WoodSpring Suites St. Louis Arnold
- Days Inn by Wyndham Dyersburg
- Comfort Suites St. Louis - Sunset Hills
- Super 8 by Wyndham St. Clair MO
- Quality Inn
- Super 8 by Wyndham Eureka/Six Flags Nearby
- Quality Inn Near Six Flags St. Louis
- Holiday Inn Express Hotel & Suites Dyersburg, an IHG Hotel
- Hampton Inn St. Louis - Columbia
- Sleep Inn & Suites Dyersburg I-155
- Super 8 by Wyndham Sullivan
- Hotel 7 Inn Anna
- Super 8 by Wyndham Union
- Hampton Inn West Plains
- Econo Lodge
- Baymont by Wyndham Chester IL
- Days Inn & Suites by Wyndham Cuba
- Hampton Inn Dyersburg
- Super 8 by Wyndham Blytheville
- Hampton Inn St. Louis Southwest
- Super 8 by Wyndham West Plains
- Super 8 by Wyndham Cuba
- The Principal Hotel
- Holiday Inn Express & Suites West Plains Southwest, an IHG Hotel
- Comfort Inn US 60/63
- West Plains Motel
- Wine Country Farmhouse On the Wine 🍷 Trail! Private Lake kayaks Fire Pit 🔥
- Americas Best Value Inn Blytheville
- Quality Inn Dyersburg I-155
- Motel 6 Dyersburg, TN
- Great location just across the street from Reelfoot Lake close to boat ramps
- Mammoth Spring Lodge Motel
- Country Inn Motel
- Sullivan Inn
- Americas Best Inn - Eureka
- Lakeside View Lodge overlooking beautiful Reelfoot Lake
- Days Inn by Wyndham Blytheville
- Red Bud Country Inn
- Americas Best Value Inn Sullivan
- Parkview Motel
- Super 8 by Wyndham Waterloo
- Riverview Cabins
- Hunting Lodge located near Reelfoot Lake, TN
- The Conner House B&B