Find 5 Star Hotels in Santorini from AED 321

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Compare Santorini 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Suites of the Gods Cave Spa

5.0 star property
8.6 out of 10, Excellent, (228)
"Very nice staff, friendly. Would recommend the suites. Beautiful view & quiet. Letisia was very helpful "
The price is AED 340
AED 402 total
includes taxes & fees
27 Mar - 28 Mar
Suites of the Gods Cave Spa

Volcano View Hotel Santorini

5.0 star property
9.4 out of 10, Exceptional, (902)
"Loved the stay with the staff being great all throughout from room service cleanliness breakfast and dinning services - 5 stars for the amazing views and location "
The price is AED 524
AED 655 total
includes taxes & fees
3 Apr - 4 Apr
Volcano View Hotel Santorini

De Sol Spa Hotel

5.0 star property
9.2 out of 10, Wonderful, (490)
"The hotel is clean, staff are friendly and service are great. And the kids love the jacuzzi. "
The price is AED 410
AED 526 total
includes taxes & fees
5 Apr - 6 Apr
De Sol Spa Hotel

Andronis Arcadia Hotel

5.0 star property
9.6 out of 10, Exceptional, (154)
"Excellent property, outstanding service, wonderful breakfast "
Andronis Arcadia Hotel

NOŪS Santorini

5.0 star property
9.8 out of 10, Exceptional, (79)
"Great pool and central "
NOŪS Santorini

Cresanto Luxury Suites

5.0 star property
9.6 out of 10, Exceptional, (224)
"We loved this hotel. The room was modern and spacious and gorgeous balcony with hot tub. The breakfast was also great. The only drawback is that it’s not caldera facing. It’s ocean facing the other side of the island "
Cresanto Luxury Suites

Santo Mine Oia Suites

5.0 star property
9.2 out of 10, Wonderful, (32)
"Our stay at Santo Mine Oia Suites was very pleasant. The view was stunning, the service was wonderful and it was very easy to walk to the main strip. Great resort, I would recommend it!"
Santo Mine Oia Suites

Andronis Concept Wellness Resort

5.0 star property
9.6 out of 10, Exceptional, (101)
"Lovely hotel, stayed in a finesse suite. Great views of Oia from private pool. Staff absolutely amazing and made our stay extremely personal and nothing too much trouble for them to organise. Breakfast and lunch meals were lovingly produced. Totally enjoyed our stay and couldn’t recommend enough. Especially Zoe who was our designated personal contact. "
Andronis Concept Wellness Resort

Skyfall Suites - Adults Only

5.0 star property
9.8 out of 10, Exceptional, (209)
"Unforgettable stay at Skyfall Suites! Immaculate rooms, stunning views, and exceptional customer service. Staff helped with car rentals and activity recommendations. Delicious dinner at the on-site restaurant. Would definitely return! Highly recommended."
Skyfall Suites - Adults Only

Esperas Santorini

5.0 star property
9.6 out of 10, Exceptional, (259)
"Beautiful hotel. Amazing views and spacious room/ clean room. Breakfast was delicious and pool area was great. Staff was very accommodating. Highly recommend this hotel. "
The price is AED 705
AED 860 total
includes taxes & fees
15 Apr - 16 Apr
Esperas Santorini

Santorini Kastelli Resort

5.0 star property
9.4 out of 10, Exceptional, (280)
"This stay was the best that I've had in any country that I have been to. One of my favorite parts about my stay was Kasjan. he was absolutely amazing. I would stay here again only if Kasjan comes back for the season. He really made our GUYS trip. "
Santorini Kastelli Resort

Canaves Epitome - Small Luxury Hotels of the World

5.0 star property
9.8 out of 10, Exceptional, (138)
"The service was great and the staff was so helpful, amenities and all extras stupendous!"
The price is AED 2,049
AED 2,387 total
includes taxes & fees
25 Apr - 26 Apr
Canaves Epitome - Small Luxury Hotels of the World

Aqua Luxury Suites

5.0 star property
9.2 out of 10, Wonderful, (195)
"Great Suit !"
The price is AED 579
AED 660 total
includes taxes & fees
26 Mar - 27 Mar
Aqua Luxury Suites

Grace Hotel, Auberge Resorts Collection

5.0 star property
9.8 out of 10, Exceptional, (111)
"Gorgeous property, exceptional service, delicious food. Imerovigli was a perfect location for us. "
Grace Hotel, Auberge Resorts Collection

Andronis Boutique Hotel

5.0 star property
10.0 out of 10, Exceptional, (243)
"Great hotel"
The price is AED 1,543
AED 1,812 total
includes taxes & fees
19 Apr - 20 Apr
Andronis Boutique Hotel

North Santorini - A Luxury Spa Hotel

5.0 star property
9.8 out of 10, Exceptional, (61)
"I had an amazing time at the North Santorini Spa hotel! Not only is this hotel beautiful but it is very clean. The staff at the hotel are friendly, helpful and always made themselves available whenever I needed them. If you’re looking for a peaceful and luxury getaway this is the place for you!"
North Santorini - A Luxury Spa Hotel

Katikies Santorini - The Leading Hotels Of The World

5.0 star property
9.6 out of 10, Exceptional, (325)
"This hotel exceeded all our expectations! Our suite was tastefully decorated and exceptionally comfortable, with a breathtaking view that made each morning unforgettable. The breakfast spread was outstanding, offering a variety of fresh, delicious options to start the day right. The staff were incredibly welcoming and attentive, always ready to help with a smile. Every detail was thoughtfully designed to make guests feel special. I highly recommend this hotel to anyone looking for a luxurious,...
The price is AED 1,859
AED 2,127 total
includes taxes & fees
26 Mar - 27 Mar
Katikies Santorini - The Leading Hotels Of The World

Canaves Oia Suites - Small Luxury Hotels of the World

5.0 star property
9.8 out of 10, Exceptional, (116)
"Absolutely breathtaking stay Fantastic complimentary breakfast with incredible views Staff is lovely Great location "
The price is AED 2,096
AED 2,440 total
includes taxes & fees
2 Apr - 3 Apr
Canaves Oia Suites - Small Luxury Hotels of the World

The Saint Hotel

5.0 star property
9.8 out of 10, Exceptional, (136)
"My wife and I loved staying here! The staff were incredibly nice and always willing to help. The views you can’t beat. We stayed in the majestic suite which had a smaller balcony but the biggest size room space. We will definitely be coming back! "
The price is AED 2,460
AED 2,853 total
includes taxes & fees
15 Apr - 16 Apr
The Saint Hotel

Aeifos Boutique Hotel

5.0 star property
9.8 out of 10, Exceptional, (74)
"Beautiful hotel! Very accessible for my dad who had a bad knee, and such lovely & accomodating staff! We felt very looked after here, the view from this hotel of the sunset over the caldera was unbelievable. They catered to my allergies very well also. 10/10 no complaints! "
The price is AED 596
AED 737 total
includes taxes & fees
13 Apr - 14 Apr
Aeifos Boutique Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santorini

Blissful weather and postcard-perfect villages atop soaring cliffs: This Greek island is a scenic spot for a peaceful getaway.

Santorini showing general coastal views and a bay or harbor

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Santorini?
There are many different pricing options for 5-star hotels in Santorini on Expedia. The amount you pay will depend on your vacation dates, trip length and other factors. Compare all of the available accommodations for your preferred dates and use our pricing and other filters to score the perfect upscale stay.

  • Search for the lowest price per night from AED 321

What makes a hotel 5 stars in Santorini?
From fine dining restaurants and fitness centers to pools and dreamy bedding, the 5-star experience in Santorini is all about comfort and luxury. But it calls for more than just top-notch conveniences to receive a 5-star rating. Hotels also have to deliver exceptional guest-centric services like in-room beauty treatments, dry cleaning and laundry and 24-hour concierge services.
Are there any 5-star all-inclusive resorts in Santorini?
Find an indulgent retreat that includes your lodging, meals, bar and entertainment in Santorini with Expedia’s filters. Search for resorts rated 5 stars and select the “All inclusive” filter. Make sure you check what’s included in the price. That way, you can take full advantage of the premium perks on offer from the moment you arrive.
Are there any 5-star vacation rentals in Santorini?
Although you won’t find any 5-star vacation rentals in Santorini on our site, we have a range of stays that promise a fabulous getaway. Find one that matches your needs by searching our vacation rentals in Santorini.
What are the top 5-star hotels near Santorini National Airport (JTR)?
On your next visit to Santorini, have a look at Smy Mediterranean White Santorini. Around 2 kilometers east from Santorini National Airport (JTR), this 5-star hotel offers both convenience plus loads of luxury.