Find 5 Star Hotels in Mendrisio from AED 328

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Check availability on Mendrisio 5 Star Hotels

Our top choices for Mendrisio 5-star hotels

Villa (Sola Cabiati) | Premium bedding, down comforters, minibar, in-room safe
Grand Hotel Tremezzo

Grand Hotel Tremezzo

Grand Hotel Tremezzo
5.0 star property
Tremezzina
9.8 out of 10, Exceptional, (87)
"Nicest hotel I’ve ever stayed in - unbelievable experience all around."
United States
Jordan
Grand Hotel Tremezzo
Indoor pool, open 8:00 AM to 8:00 PM, sun loungers
Hotel Splendide Royal

Hotel Splendide Royal

Hotel Splendide Royal
5.0 star property
Loreto
9.4 out of 10, Exceptional, (461)
"Great place to stay "
United States
carla
The price is AED 1,120
AED 1,206 total
includes taxes & fees
16 Dec - 17 Dec
Hotel Splendide Royal
2 restaurants, lunch served
Grand Hotel Villa Serbelloni

Grand Hotel Villa Serbelloni

Grand Hotel Villa Serbelloni
5.0 star property
Historic Center
9.2 out of 10, Wonderful, (550)
"The staff were wonderful and the hotel was impeccable. All amenities were extremely thoughtful."
United States
Brian
Grand Hotel Villa Serbelloni
Terrace/patio
Mandarin Oriental, Lago di Como

Mandarin Oriental, Lago di Como

Mandarin Oriental, Lago di Como
5.0 star property
Blevio
9.4 out of 10, Exceptional, (482)
"The staff was amazing "
United States
Maria
Mandarin Oriental, Lago di Como
Premium bedding, down comforters, minibar, in-room safe
Grand Hotel Villa Castagnola

Grand Hotel Villa Castagnola

Grand Hotel Villa Castagnola
5.0 star property
Cassarate
9.6 out of 10, Exceptional, (393)
"Amazing hotel and a truly special place."
United Kingdom
steve
The price is AED 1,963
AED 2,081 total
includes taxes & fees
3 Jan - 4 January 2026
Grand Hotel Villa Castagnola
Suite | Down comforters, in-room safe, laptop workspace, soundproofing
Grand Hotel Campione

Grand Hotel Campione

Grand Hotel Campione
5.0 star property
Campione d'Italia
9.0 out of 10, Wonderful, (166)
"Very good breakfast and welcoming atmosphere "
United Kingdom
Ehab
Grand Hotel Campione
Front of property
Villa Principe Leopoldo

Villa Principe Leopoldo

Villa Principe Leopoldo
5.0 star property
Loreto
9.2 out of 10, Wonderful, (342)
"The breakfast served in the dining room is amazing, excellent selection of any kind of food you may eat. The service and staff are exquisite. Only the building needs to be refreshed and the rooms to be equipped with USB plugs or international plugs fur foreign travelers. "
United States
Alessandra
Villa Principe Leopoldo
Junior Suite, Terrace, Lake View | Minibar, in-room safe, blackout drapes, free WiFi
Swiss Diamond Boutique Hotel La Romantica

Swiss Diamond Boutique Hotel La Romantica

Swiss Diamond Boutique Hotel La Romantica
5.0 star property
Melide
9.8 out of 10, Exceptional, (17)
"Beautiful location and friendly staffs are impressive. Would love to visit again. "
United States
Susan
The price is AED 1,388
AED 1,484 total
includes taxes & fees
14 Jan - 15 January 2026
Swiss Diamond Boutique Hotel La Romantica
Indoor pool, seasonal outdoor pool
Grand Hotel Victoria Concept & Spa, by R Collection Hotels

Grand Hotel Victoria Concept & Spa, by R Collection Hotels

Grand Hotel Victoria Concept & Spa, by R Collection Hotels
5.0 star property
Menaggio
9.8 out of 10, Exceptional, (95)
"Beautiful property with excellent service."
United States
Gabriel
Grand Hotel Victoria Concept & Spa, by R Collection Hotels
2 restaurants, breakfast served
Swiss Diamond Hotel & SPA

Swiss Diamond Hotel & SPA

Swiss Diamond Hotel & SPA
5.0 star property
Vico Morcote
9.0 out of 10, Wonderful, (435)
"Beautiful property, very friendly and helpful staff. The breakfast buffet was excellent! We had a wonderful time."
Canada
Sabrina
Swiss Diamond Hotel & SPA
Indoor pool, outdoor pool, sun loungers
ARIA Retreat & SPA - The Leading Hotels of the World, located within Parco San Marco Resort

ARIA Retreat & SPA - The Leading Hotels of the World, located within Parco San Marco Resort

ARIA Retreat & SPA - The Leading Hotels of the World, located within Parco San Marco Resort
5.0 star property
Porlezza
9.8 out of 10, Exceptional, (78)
"This was the nicest hotel that we have ever stayed at, and the food was out of this world."
United States
Jeremy
The price is AED 3,423
AED 3,765 total
includes taxes & fees
2 Jan - 3 January 2026
ARIA Retreat & SPA - The Leading Hotels of the World, located within Parco San Marco Resort
Rooftop bar
Palazzo Venezia

Palazzo Venezia

Palazzo Venezia
5.0 star property
Como City Centre
9.8 out of 10, Exceptional, (119)
"The hotel was in a perfect location. Next to the lake. Nice rooftop bar and dinner at the hotel restaurant was absolutely delicious. Super friendly staff. Easy access to ferries. Would definitely stay here again. "
United States
Susana
Palazzo Venezia
Outdoor dining
Passalacqua

Passalacqua

Passalacqua
5.0 star property
Moltrasio
10.0 out of 10, Exceptional, (18)
"Entire hotel is a 12/10 but add in that they have ALL the Dyson products in each room!!! "
United States
bernard
Passalacqua
Front of property
Bianca Relais - by R Collection Hotels

Bianca Relais - by R Collection Hotels

Bianca Relais - by R Collection Hotels
5.0 star property
Oggiono
9.8 out of 10, Exceptional, (50)
"simple n modern design beautiful lakeview"
Hong Kong SAR China
Po Mei
The price is AED 1,716
AED 1,888 total
includes taxes & fees
19 Dec - 20 Dec
Bianca Relais - by R Collection Hotels
Indoor pool
The View Lugano

The View Lugano

The View Lugano
5.0 star property
Paradiso
9.6 out of 10, Exceptional, (157)
"Wonderful hotel, can’t praise it enough. Look forward to our next stay! "
United States
Jonathan
The price is AED 2,413
AED 2,547 total
includes taxes & fees
21 Dec - 22 Dec
The View Lugano
3 restaurants, breakfast, lunch, dinner served; Italian cuisine
Nuvole Garden Hotel

Nuvole Garden Hotel

Nuvole Garden Hotel
5.0 star property
Brunate
8.4 out of 10, Very Good, (8)
"Excellent service and environment. Such a resort on top of lake Como with full view. Highly recommended. "
Hong Kong SAR China
Tsun
The price is AED 1,852
AED 2,081 total
includes taxes & fees
15 Dec - 16 Dec
Nuvole Garden Hotel
Terrace/patio
Hotel Eden Roc

Hotel Eden Roc

Hotel Eden Roc
5.0 star property
Ascona
9.4 out of 10, Exceptional, (129)
"Super Hotel! "
Germany
Stephan
Hotel Eden Roc
Junior Suite, Lake View, Annex Building (in grotta) | Lake view
Villa Lario Resort Mandello

Villa Lario Resort Mandello

Villa Lario Resort Mandello
5.0 star property
Mandello del Lario
9.8 out of 10, Exceptional, (38)
"Great well run resort"
United States
gordon
Villa Lario Resort Mandello
Exterior
Resort Collina d'Oro

Resort Collina d'Oro

Resort Collina d'Oro
5.0 star property
Collina d'Oro
9.2 out of 10, Wonderful, (163)
"Excellent resort"
United States
Gregory
Resort Collina d'Oro
Exterior
Giardino Ascona

Giardino Ascona

Giardino Ascona
5.0 star property
Ascona
9.6 out of 10, Exceptional, (75)
"We loved being there and being taken care of by amazing staff."
United States
Karin
Giardino Ascona
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mendrisio.
First Hotel Malpensa

First Hotel Malpensa

Via Baracca 34 Somma Lombardo VA
The price is AED 314 per night from Dec 15 to Dec 16
AED 314
AED 363 total
15 Dec - 16 Dec
includes taxes & fees
8.6/10 Excellent! (1,008 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Mendrisio

Tucked between Lake Lugano and Generoso Mount, this charming town invites you to explore its cultural treasures at Museum d'Art and Galleria Baumgartner. Bargain hunters flock to FoxTown Factory Stores while nature lovers can discover the UNESCO-listed Monte San Giorgio with its remarkable fossil deposits.

See all hotels in Mendrisio
Panoramic aerial view of a Swiss city. Mendrisio with to the right the church of Saints Cosmas and Damian, Switzerland

Top Mendrisio Hotel Reviews

Grand Hotel Villa Serbelloni

Grand Hotel Villa Serbelloni

10/10 Excellent
"The staff were wonderful and the hotel was impeccable. All amenities were extremely thoughtful."
Brian 1-night trip
Posted 2 months ago
Grand Hotel Villa Serbelloni

Frequently asked questions

What are the best 5-star hotels in Mendrisio?
According to Expedia guest reviews, Swiss Diamond Hotel & SPA, Resort Collina dOro and The View Lugano are some of the top 5-star hotels in Mendrisio. Featuring top-of-the-line amenities and excellent service, you'll enjoy a luxurious and comfortable stay.
How much does it cost to stay in a 5-star hotel in Mendrisio?
How much you pay for a 5-star hotel in Mendrisio depends on factors such as when you plan to go and the length of your getaway. A top tip for landing an awesome deal? Use our pricing filters to compare all of the available accommodations for your selected dates.

  • Search for the lowest price per night from AED 328

What makes a hotel 5 stars in Mendrisio?
Faultless guest service is the defining feature of every 5-star hotel in Mendrisio. From the second you arrive, staff ensure your every need is met, whether recommending activities and tours or providing a turn-down service. On top of that, hotels have to offer upscale conveniences to be considered for a 5-star rating. These can include luxury baths, an on-site spa, swimming pools, fine dining kitchens and knowledgeable concierge.

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