Find 5 Star Hotels in Key Largo, FL

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Check availability on Key Largo 5 Star Hotels

Compare Key Largo 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Baker's Cay Resort Key Largo, Curio Collection by Hilton

4.0 star property
8.6 out of 10, Excellent, (1004)
"Beautiful resort and beach. Was very clean and comfortable. "
The price is AED 1,372
AED 1,746 total
includes taxes & fees
29 Jan - 30 Jan
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Playa Largo Resort & Spa, Autograph Collection

4.5 star property
9.0 out of 10, Wonderful, (1001)
"We stayed at Playa Largo Resort & Spa for our 35th wedding anniversary. They left a gift of wine and macaroons/chocolates in our room! They also helped me to arrange for singers (Gaby & Milly) to sing our song for us! It couldn't have been more perfect. They do apparently have a daily resort fee that I was unaware of though..."
The price is AED 1,778
AED 2,202 total
includes taxes & fees
4 Feb - 5 Feb
Playa Largo Resort & Spa, Autograph Collection

Marina Del Mar Resort and Marina

2.5 star property
8.4 out of 10, Very Good, (1319)
"That’s hotel is awesome , clean,breakfast is good , near restaurant , and everything. I would like to come back soon. The staff fenomenal "
The price is AED 401
AED 451 total
includes taxes & fees
26 Jan - 27 Jan
Marina Del Mar Resort and Marina

Bayside Inn Key Largo

3.0 star property
8.6 out of 10, Excellent, (1402)
"I like the location. Every staff person was friendly and helpful."
The price is AED 621
AED 790 total
includes taxes & fees
23 Jan - 24 Jan
Bayside Inn Key Largo

Rock Reef Resort

2.5 star property
9.2 out of 10, Wonderful, (1010)
"Great location and staff"
The price is AED 820
AED 922 total
includes taxes & fees
23 Jan - 24 Jan
Rock Reef Resort

Reefhouse Resort & Marina

3.5 star property
9.2 out of 10, Wonderful, (1257)
"Excellent location, very clean, nice place and stay"
The price is AED 777
AED 1,021 total
includes taxes & fees
23 Jan - 24 Jan
Reefhouse Resort & Marina

The Pelican Key Largo Cottages

2.0 star property
8.6 out of 10, Excellent, (1001)
"We enjoyed our stay. Ice is not free though, so if you want it, bring your quarters. "
The price is AED 460
AED 517 total
includes taxes & fees
30 Jan - 31 Jan
The Pelican Key Largo Cottages

Waterside Suites & Marina

3.5 star property
8.6 out of 10, Excellent, (1005)
"Excellent accommodation with service to match!"
The price is AED 584
AED 657 total
includes taxes & fees
23 Jan - 24 Jan
Waterside Suites & Marina

Key Largo Inn

3.0 star property
6.4 out of 10, (1000)
"Very last minute overnight stay in the area. We took the chance and made a reservation as the price was right. Older motel and it was rundown but clean! Desk staff was accommodating to our last minute request/need. We would stay there again if needed. "
The price is AED 471
AED 530 total
includes taxes & fees
26 Jan - 27 Jan
Key Largo Inn

Holiday Inn Key Largo, an IHG Hotel

3.0 star property
8.4 out of 10, Very Good, (1005)
"The hotel was really nice, loved the outdoor heated pool at night! The beds were comfortable, and generally a clean room. The big disappointment was the cleanliness of the tile floor in our room. It was dirty and our feet needed to be washed before getting into bed. "
The price is AED 694
AED 781 total
includes taxes & fees
23 Jan - 24 Jan
Holiday Inn Key Largo, an IHG Hotel

Hampton Inn Key Largo Manatee Bay

2.5 star property
8.6 out of 10, Excellent, (1006)
"Nice beach. Great staff."
The price is AED 694
AED 781 total
includes taxes & fees
29 Jan - 30 Jan
Hampton Inn Key Largo Manatee Bay

Drift Hotel

2.5 star property
9.0 out of 10, Wonderful, (1001)
"Location"
The price is AED 657
AED 740 total
includes taxes & fees
29 Jan - 30 Jan
Drift Hotel

Gilbert's Resort

2.0 star property
8.6 out of 10, Excellent, (1002)
"Gilbert’s is always a fun stop when you are entering or leaving the Keys! The staff is very nice. The rooms are clean and the first floor rooms with decks are always a bonus. The drinks are pretty good but restaurant leaves a lot to be desired so I would stick with the basics. "
The price is AED 1,062
AED 1,194 total
includes taxes & fees
23 Jan - 24 Jan
Gilbert's Resort

Sunset Cove Beach Resort

2.5 star property
8.8 out of 10, Excellent, (1001)
"Nice and quaint little units. Very clean and safe."
The price is AED 764
AED 859 total
includes taxes & fees
26 Jan - 27 Jan
Sunset Cove Beach Resort

Dove Creek Resort & Marina, Trademark Collection by Wyndham

3.0 star property
7.6 out of 10, Good, (1003)
"The property was nice. Room was super clean and a great view. The only bad thing to say is the parking is inadequate but I would stay again"
The price is AED 621
AED 815 total
includes taxes & fees
28 Jan - 29 Jan
Dove Creek Resort & Marina, Trademark Collection by Wyndham

Amoray Dive Resort

2.0 star property
9.0 out of 10, Wonderful, (1000)
"Great overall "
The price is AED 621
AED 698 total
includes taxes & fees
27 Jan - 28 Jan
Amoray Dive Resort

Courtyard by Marriott Key Largo

3.0 star property
8.0 out of 10, Very Good, (1000)
"Decent hotel "
The price is AED 621
AED 699 total
includes taxes & fees
26 Jan - 27 Jan
Courtyard by Marriott Key Largo

Bay Harbor Lodge

3.0 star property
9.2 out of 10, Wonderful, (619)
"Great place to stay"
The price is AED 826
AED 930 total
includes taxes & fees
23 Jan - 24 Jan
Bay Harbor Lodge

Azul del Mar

3.5 star property
9.0 out of 10, Wonderful, (656)
"The staff was ABSOLUTELY amazing. Kim and Miguel were beyond helpful and so friendly. The room view was incredible, the amenities were great. The location was in a great convenient to other activities. The room was very spacious, yet somewhat outdated. We loved our stay and highly recommend to other guests. It is tucked away so you feel like you are in your own secluded private resort. "
The price is AED 951
AED 1,070 total
includes taxes & fees
29 Jan - 30 Jan
Azul del Mar

Kona Kai Resort and Gallery - Adults Only

2.5 star property
9.8 out of 10, Exceptional, (225)
"I felt like I was in paradise, Kathy is an incredible host, but everyone is very friendly. "
The price is AED 1,245
AED 1,504 total
includes taxes & fees
3 Feb - 4 Feb
Kona Kai Resort and Gallery - Adults Only
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Frequently asked questions

How much does it cost to stay in a 5-star hotel in Key Largo?
You’ll find a variety of pricing options for a 5-star hotel in Key Largo on Expedia. How much you’ll pay will depend on when you travel, trip length and other factors. Compare all of the available properties for your desired dates and make use of our pricing and other filters to find the perfect high-end stay.

  • Search for the lowest price per night

What makes a hotel 5 stars in Key Largo?
Flawless guest service is the foundation of every 5-star hotel in Key Largo. From the moment you arrive, staff attend to your every need, whether arranging customized tours or providing in-room beauty treatments. Additionally, hotels must feature upscale amenities to qualify for a 5-star rating. These can include luxury baths, a wellness center, pools, gastronomic restaurants and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Key Largo?
Our filter tool is the quickest way to search for exactly what you’re looking for. Select “5-star” and “All inclusive” to see the most upscale resorts in Key Largo where your meals, lodging, activities and entertainment are included in the upfront price. At these escapes, your trip is absolute indulgence from the moment you arrive.
Are there any 5-star vacation rentals in Key Largo?
Although there aren’t any 5-star vacation rentals in Key Largo on our site, we have a range of properties that promise an awesome getaway. Discover one that matches your needs by checking out our vacation rentals in Key Largo.