Find 5 Star Hotels in Downtown St. Louis, MO from AED 400

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Compare Downtown St. Louis 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Four Seasons Hotel St Louis
Terrace/patio

Four Seasons Hotel St Louis

5.0 star property
9.4 out of 10, Exceptional, (979)
"Nice staff, amazing room"
The price is AED 1,377
AED 1,611 total
includes taxes & fees
25 Jan - 26 Jan
Four Seasons Hotel St Louis
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Downtown St. Louis.
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

315 Chestnut St, St. Louis, MO
The price is AED 400 per night from Jan 12 to Jan 13
AED 400
AED 472 total
includes taxes & fees
12 Jan - 13 Jan
8.4/10 Very Good! (3,536 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the best 5-star hotels in Downtown St. Louis?
Experience top-class amenities and refined service at Four Seasons Hotel St Louis. Located around the St. Louis neighborhood of Downtown St. Louis, this 5-star hotel is a leading choice based on reviews by Expedia guests.
How much does it cost to stay in a 5-star hotel in Downtown St. Louis?
How much you pay for a 5-star hotel in Downtown St. Louis can vary depending on when you want to travel and how long you plan to be away, among several factors. Use our price per night filter and other search tools to land the best rate on an indulgent stay.

  • Search for the lowest price per night from AED 400

What makes a hotel 5 stars in Downtown St. Louis?
In Downtown St. Louis, a hotel needs to provide a certain amount of upscale conveniences to earn a 5-star rating. These can include on-site gyms, spas and saunas, gourmet restaurants, luxury bathroom products, premium bedding and more. What also sets 5-star hotels apart is their guest-focused standard of service. You can look forward to things like in-room massages, nightly turn-down services and concierge services. Some may also offer additional touches like welcome gifts.
Are there any 5-star all-inclusive resorts in Downtown St. Louis?
Our filter tool is the quickest way to narrow down what you want. Select “5-star” and “All inclusive” to see the most luxurious resorts in Downtown St. Louis where your meals, room, entertainment and activities are included in the upfront price. At these escapes, your vacation is pure leisure from the moment you check in.
What are the top 5-star spa hotels in Downtown St. Louis?
Spend your next vacation being pampered and indulged at Four Seasons Hotel St Louis. This 5-star spa property in the Downtown St. Louis area offers a range of treatments and experiences that inspire rejuvenation, relaxation and self-care.
Are there any 5-star vacation rentals in Downtown St. Louis?
Our site doesn’t have any 5-star vacation rentals in Downtown St. Louis. However, you will still find a few top-rated retreats where the only thing on your agenda will be to kick back and enjoy yourself. View what’s available by searching through our vacation rentals in Downtown St. Louis.