Find 5 Star Hotels in Downtown St. Louis, MO from AED 386

Experience top-class amenities and refined service at Four Seasons Hotel St Louis. Located around the St. Louis neighborhood of Downtown St. Louis, this 5-star hotel is a leading choice based on reviews by Expedia guests.

How much you pay for a 5-star hotel in Downtown St. Louis can vary depending on when you want to travel and how long you plan to be away, among several factors. Use our price per night filter and other search tools to land the best rate on an indulgent stay.

• Search for the lowest price per night from AED 386

In Downtown St. Louis, a hotel needs to provide a certain amount of upscale conveniences to earn a 5-star rating. These can include on-site gyms, spas and saunas, gourmet restaurants, luxury bathroom products, premium bedding and more. What also sets 5-star hotels apart is their guest-focused standard of service. You can look forward to things like in-room massages, nightly turn-down services and concierge services. Some may also offer additional touches like welcome gifts.

Our filter tool is the quickest way to narrow down what you want. Select “5-star” and “All inclusive” to see the most luxurious resorts in Downtown St. Louis where your meals, room, entertainment and activities are included in the upfront price. At these escapes, your vacation is pure leisure from the moment you check in.

Spend your next vacation being pampered and indulged at Four Seasons Hotel St Louis. This 5-star spa property in the Downtown St. Louis area offers a range of treatments and experiences that inspire rejuvenation, relaxation and self-care.

Our site doesn’t have any 5-star vacation rentals in Downtown St. Louis. However, you will still find a few top-rated retreats where the only thing on your agenda will be to kick back and enjoy yourself. View what’s available by searching through our vacation rentals in Downtown St. Louis.