Southern Illinois Vacations
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Where to stay in Southern Illinois
Find the best Southern Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southern Illinois
Eastport
If you're spending some time in Eastport, Gateway Conference Center and Splash City Family Waterpark are top sights worth seeing.
Find the Best Southern Illinois Vacation Packages
Southern Illinois Hotel Deals
Drury Plaza Hotel Mt. Vernon
145 North 44th Street , Mount Vernon, IL
Fully refundableReserve now, pay when you stay
The price is AED 380 per night from Apr 6 to Apr 7
AED 380
AED 429 total
includes taxes & fees
6 Apr - 7 Apr
9.6/10 Exceptional! (1,253 reviews)
"I often stay at this location when traveling for work. It is always exceptionally the clean, the staff is friendly, and I have never had anything less than a wonderful experience. When I am in Mt Vernon, I will never stay anywhere else!"
Reviewed on 7 March 2025
Super 8 by Wyndham O'Fallon
1100 Eastgate Dr, O'Fallon, IL
Fully refundableReserve now, pay when you stay
The price is AED 190 per night from Mar 16 to Mar 17
AED 190
AED 219 total
includes taxes & fees
16 Mar - 17 Mar
7.6/10 Good! (1,003 reviews)
"Nice big bed with lots of pillows, good shower pressure and a quiet nite except for the fridge which I had to unplug to sleep"
Reviewed on 7 March 2025
Drury Inn & Suites St. Louis O'Fallon, IL
1118 Central Park Drive, O'Fallon, IL
Fully refundableReserve now, pay when you stay
The price is AED 413 per night from Mar 16 to Mar 17
AED 413
AED 479 total
includes taxes & fees
16 Mar - 17 Mar
9.4/10 Exceptional! (1,011 reviews)
"The lady at the front desk was very rude from the start. Would not use the credit card on file due to my husband not being there to sign. I’ve never had this issue before."
Reviewed on 7 March 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Southern Illinois
Southern Illinois University
4.5/5(173 reviews)
Take a campus tour or just explore the area of Southern Illinois University, during your trip to Carbondale. Check out the shops and top-notch restaurants in this family-friendly area.
Garden of the Gods Recreation Area
5/5(6 reviews)
Explore the great outdoors at Garden of the Gods Recreation Area, a lovely green space in Equality. While you're in the area, stroll along the riverfront.
Superman Statue
4.5/5(104 reviews)
You can learn about the history of Metropolis when you stop by Superman Statue. Check out the casinos and top-notch restaurants in this family-friendly area.