
Seneca Vacations
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Where to stay in Seneca
Find the best Seneca areas and neighborhoods for the activities you enjoy most. Learn more about Seneca

Serenity Bay
Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.
Find the Best Seneca Vacation Packages
Seneca Hotel Deals

Lakeside Lodge Clemson
13500 Clemson Blvd, Seneca, SC
Fully refundableReserve now, pay when you stay
The price is AED 400 per night from Mar 24 to Mar 25
AED 400
AED 494 total
includes taxes & fees
24 Mar - 25 Mar
8.8/10 Excellent! (815 reviews)
"Thx"
Reviewed on 19 March 2025

Hampton Inn & Suites Seneca-Clemson Area
1011 East North 1st Street, Seneca, SC
Fully refundableReserve now, pay when you stay
The price is AED 445 per night from Mar 30 to Mar 31
AED 445
AED 490 total
includes taxes & fees
30 Mar - 31 Mar
9.2/10 Wonderful! (585 reviews)
"Very clean and the staff is very helpful"
Reviewed on 12 March 2025

Tru by Hilton Seneca Clemson
13050 Clemson Blvd, Seneca, SC
Fully refundableReserve now, pay when you stay
The price is AED 403 per night from Mar 31 to Apr 1
AED 403
AED 443 total
includes taxes & fees
31 Mar - 1 Apr
9.2/10 Wonderful! (682 reviews)
Nice
"Mac was awesome! Breakfast has a large selection and it was good."
Reviewed on 18 March 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Discover the most popular places to visit in Seneca
Applewood Shopping Center
You can do some window-shopping at Applewood Shopping Center during your visit to Seneca. Amble around this family-friendly area's lakeside or attend a sporting event.