Santa Ana Vacations

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Santa Ana Hotel Deals

Barceló Guatemala City
Barceló Guatemala City
4.5 out of 5
7 Avenida 15-45, Zona 9, Guatemala City, Guatemala
The price is AED 298 per night from Apr 20 to Apr 21
AED 298
AED 364 total
includes taxes & fees
20 Apr - 21 Apr
9/10 Wonderful! (2,777 reviews)
"What a grand hotel and so close to the airport!"

Reviewed on 31 March 2025

Barceló Guatemala City
Wyndham Garden Guatemala City
Wyndham Garden Guatemala City
4 out of 5
1a Avenida 12-46 Zona 10, Guatemala City, Guatemala
Fully refundableReserve now, pay when you stay
The price is AED 284 per night from Apr 20 to Apr 21
AED 284
AED 346 total
includes taxes & fees
20 Apr - 21 Apr
8.8/10 Excellent! (1,282 reviews)
"Cleaning services breakfast"

Reviewed on 31 March 2025

Wyndham Garden Guatemala City
Hotel Museo Spa Casa Santo Domingo
Hotel Museo Spa Casa Santo Domingo
4.5 out of 5
3a Calle Oriente No 28 A, Antigua Guatemala, Sacatepequez
Fully refundableReserve now, pay when you stay
The price is AED 805 per night from Apr 6 to Apr 7
AED 805
AED 1,027 total
includes taxes & fees
6 Apr - 7 Apr
9.2/10 Wonderful! (1,004 reviews)
"Great location with only a few block walk to museums, dining, entertainment and historic sites. Hotel itself is a great historic site with access to 6 museums on property. In addition, the food and bar were great locations on site with a very appealing atmosphere. We had an upgraded room which provided ..."

Reviewed on 1 April 2025

Hotel Museo Spa Casa Santo Domingo
See all 1,045 properties in Santa Ana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Ana vacation package cost?
You can pick up a vacation package to this destination on Expedia. However, how much your vacation to Santa Ana costs will depend on the season, hotel choice and length of stay.
What are the cheapest months to go to Santa Ana?
If you’d like to snag a cheap Santa Ana vacation package, consider visiting in June, September and October. You’ll usually find better prices on accommodations and flights during these months — perfect for a budget-friendly break.
How to find the best Santa Ana package deals?
Begin your search for a Santa Ana package deal by entering your destination and preferred trip dates under our “Packages” tab. Then apply some filters, like “Property type” and “Popular locations,” to tailor the results to your exact style. You can also sort by “Package discount” and discover offers that come with unbeatable savings. If you don’t find the ideal Santa Ana package deal straight away, just play around with your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santa Ana adventure underway.
Is it cheaper to book a Santa Ana vacation as a package?
An Expedia vacation package could land you great savings when compared to arranging hotels and flights individually. Better still, you can customize your Santa Ana trip to fit your exact style. Choose your preferred flight time, select the hotel type and add a car rental. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Santa Ana?
If you’re considering a spontaneous Santa Ana trip, check out our last-minute deals that can be booked up to a week before you take off. Don’t want to leave things to the last minute? You can score incredible deals on your flights and hotels by booking well in advance.
How to plan a trip to Santa Ana?

  1. Pick your travel dates: What you’d like to do in Santa Ana and your preferred season can help you decide when to travel.
  2. Work out your budget: Make sure you have enough money to cover everything from meals and transportation to flights and activities. Your hotel will probably be the largest expense during your trip to Santa Ana.
  3. Decide how long to go for: Now that you’re more familiar with Santa Ana, you can work out the ideal length of your break. Create a rough plan and give yourself enough time to get through everything on your must-do list.
  4. Bundle your accommodations and airfare: After you’ve nailed down your trip dates and duration, book the perfect Santa Ana vacation package for you.

Discover the most popular places to visit in Santa Ana

Ruins of Old Mayan Monastery destroyed during earthquake in 15th century !

Casa Santo Domingo Museum

4.5/5(223 reviews)

You can browse the exhibits at Casa Santo Domingo Museum, a museum with a story of its own, during your travels to Antigua Guatemala. Discover the volcano viewpoints and shops in this family-friendly area.

Casa Santo Domingo Museum
Central Park

Central Park

4.5/5(493 reviews)

Enjoy the volcano viewpoints and explore Central Park, a lovely green space in Antigua Guatemala. Discover the area's shops, or seek out its local tours.

Central Park
Vue du volcan de Fuego

Antigua Guatemala Cathedral

4.5/5(423 reviews)

You can find out about the history of Antigua Guatemala with a visit to Antigua Guatemala Cathedral. Discover the area's shops, or seek out its local tours.

Antigua Guatemala Cathedral