
Santa Ana Vacations
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Where to stay in Santa Ana
Find the best Santa Ana areas and neighborhoods for the activities you enjoy most. Learn more about Santa Ana

Casco Viejo
4.5/5(178 area reviews)
Unique features of Casco Viejo include the historic sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.
Santa Ana Hotel Deals

Casco View Apartments
C. 16 Oeste, Panama City, Provincia de Panamá
The price is AED 210 per night from Apr 10 to Apr 11
AED 210
AED 323 total
includes taxes & fees
10 Apr - 11 Apr
9.6/10 Exceptional! (16 reviews)
"Great accommodations. Great view. Great host."
Reviewed on 21 March 2025

Hotel Riu Plaza Panama
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is AED 437 per night from Apr 21 to Apr 22
AED 437
AED 481 total
includes taxes & fees
21 Apr - 22 Apr
9/10 Wonderful! (3,805 reviews)
Nice Hotel
"Nice hotel and recommended"
Reviewed on 31 March 2025

Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
Fully refundable
The price is AED 433 per night from May 4 to May 5
AED 433
AED 537 total
includes taxes & fees
4 May - 5 May
8.4/10 Very Good! (2,092 reviews)
"Very close to airport, friendly staff and a great resource to travelers"
Reviewed on 30 March 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Santa Ana

Multiplaza Pacific Mall
4.5/5(634 reviews)
During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Cinta Costera
4.5/5(456 reviews)
Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.

Avenida Balboa
4/5(554 reviews)
You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.