Find Family Hotels in Perryville, MO

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Check availability on Perryville Family Hotels

Tonight
24 Feb - 25 Feb
Tomorrow
25 Feb - 26 Feb
This weekend
27 Feb - 1 Mar
Next weekend
6 Mar - 8 Mar

Our top choices for Perryville family-friendly hotels

Exterior

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
2.5 star property
Perryville
9.2 out of 10, Wonderful, (561 reviews)
"Staff was friendly and the place is clean. Our stay was in late January and the air was so very dry and the static electricity from blankets & sheets was off the charts."
United States
Roger
The price is AED 335
AED 383 total
includes taxes & fees
26 Feb - 27 Feb
Holiday Inn Express & Suites Perryville by IHG
Free buffet breakfast

Holiday Inn Express Hotel & Suites Sparta by IHG

Holiday Inn Express Hotel & Suites Sparta by IHG
2.5 star property
Sparta
9.2 out of 10, Wonderful, (382 reviews)
"Great place! And excellent stay! "
United States
Casey
The price is AED 306
AED 339 total
includes taxes & fees
15 Mar - 16 Mar
Holiday Inn Express Hotel & Suites Sparta by IHG
Exterior

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (710 reviews)
"Conveniently located, clean, friendly staff."
United States
Philip
The price is AED 309
AED 335 total
includes taxes & fees
1 Mar - 2 Mar
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Lobby

Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
2.5 star property
Jackson
8.2 out of 10, Very Good, (745 reviews)
"Clean and comfortable every time. This is a “go to” hotel "
United States
Jacqulyn
The price is AED 315
AED 341 total
includes taxes & fees
26 Feb - 27 Feb
Comfort Suites Jackson-Cape Girardeau
Interior

Charming Secluded Getaway Cabin within minutes of amenities

Charming Secluded Getaway Cabin within minutes of amenities
Cape girardeau
10.0 out of 10, Exceptional, (18 reviews)
"We had a great time at Blair and her family's property. The cabin was very comfortable and as advertised. I would be happy to recommend it to others "
United States
Tammy M.
The price is AED 569
AED 1,073 total
includes taxes & fees
25 Feb - 26 Feb
Charming Secluded Getaway Cabin within minutes of amenities
Outdoor dining

Beautiful location in the secluded woods

Beautiful location in the secluded woods
Pomona
10.0 out of 10, Exceptional, (64 reviews)
"It was very nice and clean. We really enjoyed staying there. We would love to rent this place again. "
United States
susan B.
The price is AED 325
AED 617 total
includes taxes & fees
25 Feb - 26 Feb
Beautiful location in the secluded woods
Children's area

Newly remodeled house minutes away from downtown, golf courses + BIG back yard

Newly remodeled house minutes away from downtown, golf courses + BIG back yard
Farmington
10.0 out of 10, Exceptional, (24 reviews)
"Everything about this property was amazing and perfect for our family! They were so helpful with everything and our kids loved it here!!"
United States
Heaven B.
The price is AED 382
AED 805 total
includes taxes & fees
3 Mar - 4 Mar
Newly remodeled house minutes away from downtown, golf courses + BIG back yard
Beach

Your home away from home in downtown, historic Farmington!

Your home away from home in downtown, historic Farmington!
Farmington
10.0 out of 10, Exceptional, (39 reviews)
"The kitchen was fully equipped and clean. Great place to stay when visiting Farmington!"
United States
Linda B.
The price is AED 474
AED 911 total
includes taxes & fees
25 Feb - 26 Feb
Your home away from home in downtown, historic Farmington!
Interior

Cozy Haven Little Hidden Gem Sleeps 4

Cozy Haven Little Hidden Gem Sleeps 4
Ste.Genevieve
9.8 out of 10, Exceptional, (58 reviews)
"Everything was perfect!! The cutest little cottage! So cozy!! "
United States
Jo J.
The price is AED 364
AED 767 total
includes taxes & fees
28 Feb - 1 Mar
Cozy Haven Little Hidden Gem Sleeps 4
Exterior

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
2.5 star property
Murphysboro
9.4 out of 10, Exceptional, (526 reviews)
"Yes, very clean and service was great."
United States
allen
The price is AED 422
AED 469 total
includes taxes & fees
1 Mar - 2 Mar
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at family-friendly hotels in Perryville

Breakfast included
Pool

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Top Perryville Hotel Reviews

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

10/10 Excellent
"Clean and spacious room. Staff was very friendly and helpful. "
Dina 1-night trip
Posted 10 days ago
Drury Inn & Suites Jackson MO

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Frequently asked questions

What's Perryville like for family-friendly vacations?
If you've been thinking about a vacation with your kids, Perryville is a good choice. The excursions, parks, and swimming spots are just some of the things that make this a good place for family vacations. Fly into Cape Girardeau, MO (CGI-Cape Girardeau Municipal), which is located 38.3 mi (61.7 km) from the city center.
When's the best time to book a family-friendly vacation in Perryville?
The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 39°F. Average annual precipitation for Perryville is 48 inches.
What's there to see and do with your family in Perryville?
While you and the family are vacationing in Perryville, you might want to check out some of the attractions here such as Popeye Museum, Mark Twain National Forest, and Mississippi River. Make sure you have lots of time for activities like Feltz Street Park and Saint Marys Lake.