Mytilene Vacations

Book a Hotel + Flight together to unlock savings

  • Plan, book, travel with confidence

    • payments icon
    Better together
    Save up to AED 148 when you book a flight and hotel together*
    lob hotels icon
    Find the right fit
    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon
    Rest easy
    Plan, book, and manage your trip all in one place

Find the Best Mytilene Vacation Packages

Mytilene Hotel Deals

Theofilos Paradise Boutique Hotel
Theofilos Paradise Boutique Hotel
4 out of 5
7, Skra str, Hatzidimitriou Park, Mytilene, Lesvos
Fully refundableReserve now, pay when you stay
The price is AED 427 per night from Apr 27 to Apr 28
AED 427
AED 522 total
includes taxes & fees
27 Apr - 28 Apr
9.6/10 Exceptional! (136 reviews)
"Recommended for me by friends. Very comfortable and a warm and helpful receptio, which was welcome after a transatlantic flight. Staff were fluent in English. Breakfast had a good range of choices, and with a good but not overwhelming Greekpresence"

Reviewed on 23 October 2024

Theofilos Paradise Boutique Hotel
Heliotrope Hotels
Heliotrope Hotels
4 out of 5
Varia, Mytilene, Lesvos, Lesvos Island
Fully refundableReserve now, pay when you stay
The price is AED 320 per night from Apr 20 to Apr 21
AED 320
AED 392 total
includes taxes & fees
20 Apr - 21 Apr
8.4/10 Very Good! (173 reviews)
"The staff was very responsive to all requests. The breakfast buffet is abundant and good."

Reviewed on 18 October 2024

Heliotrope Hotels
Mythical Coast Wellness Retreat
Mythical Coast Wellness Retreat
5 out of 5
Agrilia, Lesvos
The price is AED 482 per night from Apr 20 to Apr 21
AED 482
AED 591 total
includes taxes & fees
20 Apr - 21 Apr
8.6/10 Excellent! (24 reviews)
"Great property with lovely views and friendly staff. Only issue is that the upper floors of some buildings are not handicapped accessible and you will have to carry luggage’s up the stairs. To avoid stay on one of the main buildings"

Reviewed on 2 August 2024

Mythical Coast Wellness Retreat
See all 155 properties in Mytilene
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Mytilene vacation package cost?
You can grab a vacation package to this top destination on Expedia. But how much your vacation to Mytilene costs will depend on the season, length of stay and hotel choice.
What are the cheapest months to go to Mytilene?
If you’re hoping to score a cheap Mytilene vacation package, consider visiting in February, March and December. You’re likely to find lower prices on flights and accommodations during these months — ideal for budget-conscious travelers.
How to find the best Mytilene package deals?
Use Expedia’s handy filters to help you find some fabulous Mytilene package deals. When you start your search, just set your maximum budget and then order the results by “Price: low to high.” If you want to save, plan your trip for midweek, or browse for Mytilene package deals in the off-season. Play around with your travel dates and you may score even better discounts. As a rule of thumb, it’s usually best to book your vacation package well in advance.
Is it cheaper to book a Mytilene vacation as a package?
An Expedia vacation package could land you great savings when compared to booking stays and flights separately. Better still, you can personalize your Mytilene escape to match your exact needs. Pick your preferred flight time, select the hotel type and add a car rental. Check out our great deals to see how much you can save.
When to book a vacation package to Mytilene?
Land incredible discounts by reserving your flights ahead of time with Expedia. If being spontaneous is more your thing, snap up one of our last-minute deals for an impromptu Mytilene escape.
How to plan a trip to Mytilene?

  1. Pick your dates: The things you want to do in Mytilene and your preferred season can help you decide when to go.
  2. Set your budget: Factor in costs such as flights, food and transportation when calculating how much to save for your trip to Mytilene. Then, choose a hotel that suits your budget, whether that’s a wallet-friendly stay or a high-end getaway.
  3. Decide your trip length: Think about how much time you’d like to spend discovering Mytilene. Plan your itinerary so you can get to all the experiences and attractions you’re interested in at a leisurely pace.
  4. Bundle your bookings: With your travel dates in place, you can combine your flights, car rental, hotels and more into a customized Mytilene vacation package.

Discover the most popular places to visit in Mytilene

Port of Mytilene

4.5/5(15 reviews)

Explore the waterfront in Mytilene with a trip to Port of Mytilene. While you're in the area, stroll along the seaside.

Port of Mytilene

Bus Station

4/5(1 review)

After visiting Bus Station, make a plan to see the other sights and activities in Mytilene. While you're in the area, stroll along the seaside.

Bus Station

Mytilini Castle

5/5(5 reviews)

Learn about the local history of Mytilene when you take a trip to Mytilini Castle. While you're in the area, stroll along the seaside.

Mytilini Castle