Search Vacation Homes in Murphysboro
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check prices for these dates
Next weekend
In two weeks
In one month
In two months
Compare 97 Vacation Homes in Murphysboro with updated reviews, rates, and availability.

Notting Hill Cottage
Notting Hill Cottage
9.6 out of 10, Exceptional, (311)

Beautiful location in the secluded woods
Beautiful location in the secluded woods
9.8 out of 10, Exceptional, (27)
The price is AED 422
AED 683 total
includes taxes & fees
6 May - 7 May

* On the Wine Trail * Hot Tub * Wi-Fi *
* On the Wine Trail * Hot Tub * Wi-Fi *
9.8 out of 10, Exceptional, (227)

Wine Trail, Cozy Cabin plus hot tub
Wine Trail, Cozy Cabin plus hot tub
9.8 out of 10, Exceptional, (94)

* Best Location on the Wine Trail! * Hiking Trail 1 min away * Wi-Fi *
* Best Location on the Wine Trail! * Hiking Trail 1 min away * Wi-Fi *
10.0 out of 10, Exceptional, (93)

Minutes from WineTrail, Giant City, Shawnee Forest - Daily Deer Viewing - Rural
Minutes from WineTrail, Giant City, Shawnee Forest - Daily Deer Viewing - Rural
10.0 out of 10, Exceptional, (115)

Paradise On The Lake ~ Luxurious Peninsula Property ~ Best View On The Lake!
Paradise On The Lake ~ Luxurious Peninsula Property ~ Best View On The Lake!
10.0 out of 10, Exceptional, (115)

Brick Estate with pool in Quiet Carbondale Neighborhood
Brick Estate with pool in Quiet Carbondale Neighborhood
9.4 out of 10, Exceptional, (85)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Other property types in Murphysboro

Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery
Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery
10.0 out of 10, Exceptional, (126)

Beautiful location in the secluded woods
Beautiful location in the secluded woods
9.8 out of 10, Exceptional, (27)
The price is AED 422
AED 683 total
includes taxes & fees
6 May - 7 May

Hot Tub - Minutes from Winetrail, SIU, Giant City, Cedar Lake, Shawnee Forest!
Hot Tub - Minutes from Winetrail, SIU, Giant City, Cedar Lake, Shawnee Forest!
10.0 out of 10, Exceptional, (37)
The price is AED 801
AED 995 total
includes taxes & fees
12 May - 13 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent reviews of Murphysboro hotels
Recent reviews of Murphysboro hotels

Drury Inn & Suites Marion
5/5 Excellent
Great time
"Amazing service and the hotel was clean. Great food for dinner and breakfast. "
A verified traveler stayed at Drury Inn & Suites Marion
Posted 1 day ago