Midtown Vacations

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Where to stay in Midtown

Find the best Midtown areas and neighborhoods for the activities you enjoy most. Learn more about Midtown
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

2 out of top 10 points of interest in this area
4/5(4,004 area reviews)

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Find hotels in Downtown St. Louis

Midtown Hotel Deals

Residence Inn by Marriott St Louis Downtown
Residence Inn by Marriott St Louis Downtown
3 out of 5
525 S Jefferson Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is AED 466 per night from Apr 6 to Apr 7
AED 466
AED 555 total
includes taxes & fees
6 Apr - 7 Apr
7.8/10 Good! (1,000 reviews)
"Our check-in was very easy and smooth. The room was clean, and very convenient with the sofa bed for our 14 yr old. The area surrounding the hotel is rather industrial but we did not feel unsafe. Conveniently located for our trip to the Arch and City Museum."

Reviewed on 24 March 2025

Residence Inn by Marriott St Louis Downtown
Element St. Louis Midtown
Element St. Louis Midtown
3 out of 5
3763 Forest Park Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is AED 514 per night from Apr 6 to Apr 7
AED 514
AED 601 total
includes taxes & fees
6 Apr - 7 Apr
9/10 Wonderful! (469 reviews)
"Beautiful hotel with professional and friendly staff. Hotel was very clean, breakfast was delicious with a variety of food choices. Within 10minutes to the majority of the activities we went to. Our room was nice, big enough for our family of 6. Only complaint was housekeeping didn’t tidy up our ..."

Reviewed on 20 March 2025

Element St. Louis Midtown
Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch
4 out of 5
315 Chestnut St, St. Louis, MO
The price is AED 386 per night from Apr 18 to Apr 19
AED 386
AED 455 total
includes taxes & fees
18 Apr - 19 Apr
8.4/10 Very Good! (3,537 reviews)
"Great stay!"

Reviewed on 23 March 2025

Hyatt Regency St. Louis at The Arch
See all 1,817 properties in Midtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Midtown

St. Louis University

St. Louis University

4.5/5(292 reviews)

Explore the campus of St. Louis University as part of your travels around St. Louis. Wander around the area's picturesque gardens or experience its great live music.

St. Louis University
The Joplin Homestead

Scott Joplin House State Historic Site

Learn about the local history of St. Louis when you spend time at Scott Joplin House State Historic Site. Experience the area's great live music or attend a baseball game.

Scott Joplin House State Historic Site
Busch Stadium

Busch Stadium

4.5/5(1,469 reviews)

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game.

Busch Stadium