Midtown Vacations

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Where to stay in Midtown

Find the best Midtown areas and neighborhoods for the activities you enjoy most. Learn more about Midtown
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

2 out of top 10 points of interest in this area
4/5(4,004 area reviews)

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Find hotels in Downtown St. Louis

Midtown Hotel Deals

Residence Inn by Marriott St Louis Downtown
Residence Inn by Marriott St Louis Downtown
3 out of 5
525 S Jefferson Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is AED 433 per night from Apr 27 to Apr 28
AED 433
AED 515 total
includes taxes & fees
27 Apr - 28 Apr
7.8/10 Good! (1,001 reviews)
"Nice area"

Reviewed on 13 April 2025

Residence Inn by Marriott St Louis Downtown
Element St. Louis Midtown
Element St. Louis Midtown
3 out of 5
3763 Forest Park Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is AED 580 per night from Apr 28 to Apr 29
AED 580
AED 679 total
includes taxes & fees
28 Apr - 29 Apr
9/10 Wonderful! (476 reviews)
Those beds though!
"Pretty nice hotel. The lobby was nice. Good sitting area. The outside patio was tight too. The breakfast was fire. The staff was pretty friendly. The bed was my favorite part. Soooooo comfortable."

Reviewed on 7 April 2025

Element St. Louis Midtown
Drury Plaza Hotel St. Louis at the Arch
Drury Plaza Hotel St. Louis at the Arch
3 out of 5
2 South 4th Street, St. Louis, MO
The price is AED 441 per night from Apr 20 to Apr 21
AED 441
AED 515 total
includes taxes & fees
20 Apr - 21 Apr
9.4/10 Exceptional! (2,447 reviews)
"EVERYTHING FROM BEGINNING TO END WAS PERFECT! THE MANAGER JOE, THE LADY WHO SERVES DRINKS DURING THE KICK BACK KITCHEN STAFF FRONT DESK EVERYONE WAS SO KIND AND HELPFUL ❤️❤️❤️ I WAS ON A SOLO TRIP FROM PITTSBURGH I WILL BE BACK"

Reviewed on 14 April 2025

Drury Plaza Hotel St. Louis at the Arch
See all 1,806 properties in Midtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Midtown

St. Louis University

St. Louis University

4.5/5(292 reviews)

Explore the campus of St. Louis University as part of your travels around St. Louis. Wander around the area's picturesque gardens or experience its fascinating museums.

St. Louis University
The Joplin Homestead

Scott Joplin House State Historic Site

Learn about the local history of St. Louis when you spend time at Scott Joplin House State Historic Site. Experience the area's great live music or attend a baseball game.

Scott Joplin House State Historic Site
Busch Stadium

Busch Stadium

4.5/5(1,469 reviews)

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed theater scene or attend a baseball game.

Busch Stadium