★ Deaconess Guesthouse – A Premier Historic Riverfront Estate in Louisville / Jeffersonville ★
Where Heritage Meets High-End Hospitality
Step into the timeless elegance of Deaconess Guesthouse, a fully restored 1800s landmark that once served as Jeffersonville’s first public hospital. Set along the scenic Ohio River, this luxurious estate blends historic charm with modern comforts, offering sweeping waterfront views and seamless access to downtown Louisville, the Bourbon Trail, and Jeffersonville’s lively riverfront district.
Designed for Elevated Gatherings
Accommodating up to 24 guests across four private units, the guesthouse features 8 thoughtfully appointed bedrooms and 6 full bathrooms. Ideal for family reunions, retreats, or special celebrations, it offers spacious living areas, gourmet kitchens, and versatile indoor-outdoor spaces that foster both connection and privacy.
Signature Amenities & Unique Touches
1. Private Hot Tub & Fire Pit – Unwind beneath the stars in a tranquil outdoor setting
2. Wraparound Porches & Riverfront Balconies – Enjoy morning coffee or sunset views over the Ohio
3. One-of-a-Kind Stargazing Dome – A magical evening retreat for kids and adults alike
4. Ample On-Site Parking – Convenient access for larger groups and hosted events
Prime Location – At the Crossroads of Culture & Nature
- Walkable Downtown Jeffersonville – Boutique shops, top-rated dining, and live music venues just steps away
- 2.5 Miles to Downtown Louisville – Explore distilleries, museums, and cultural landmarks
- Endless Outdoor Recreation – Scenic trails, riverside parks, kayaking, and more within easy reach
An Unforgettable Riverfront Experience
From peaceful mornings on the porch to evenings by the fire, Deaconess Guesthouse invites you to slow down, reconnect, and celebrate life’s most meaningful moments. Whether planning a weekend escape or a once-in-a-lifetime gathering, this exclusive estate delivers sophistication, warmth, and unforgettable hospitality.
Book your riverfront escape today and discover a stay that’s rich in history, comfort, and charm. Group discounts and event-friendly options available.
★ CONVENIENT LOCATION
The house is centrally located and is within a 10-15 minute Uber/Lyft drive to most locations:
- Big Four Walking Bridge (Connecting KY and IN) - 0.4 miles (2 mins)
- Downtown Louisville/ 4th Street Live - 2.4 miles (6 mins)
- Waterfront Park - 3.4 miles (9 mins)
- KFC Yum Center - 2.3 miles (7 mins)
- Churchill Downs (DERBY) - 7.7 miles (15 mins)
- Papa Johns Stadium (Cardinal Stadium) - 6.4 miles (11 mins)
- Kentucky Fairgrounds - 6.5 miles (10 min)
- University of Louisville - 6.5 miles (12 mins)
- Kentucky Exposition Center - 6.7 miles (11 mins)
- Louisville Airport - 8.6 miles (10 mins)
- Kentucky Kingdom - 7.4 miles (13 mins)
- Highland Festival Grounds - 8.5 miles (12 mins)
- Louisville Mega Cavern - 10.2 miles (19 mins)
- Waverly Hills Sanatorium - 17 miles (30 mins)
- Ford LAP Plant - 10.9 miles (16 mins)
- UPS Worldport - 11.2 miles (20 mins)
- Valhalla Golf Club - 19 miles (27 mins)
PROPERTY HIGHLIGHTS
★ Prime Location – Nestled in the heart of Jeffersonville, just steps from downtown and minutes to Louisville, New Albany, and Clarksville, with quick access to top dining, shopping, and entertainment.
★ Historic Elegance Meets Modern Luxury – Stay in a beautifully restored architectural gem where timeless charm blends seamlessly with upscale amenities for a one-of-a-kind experience.
★ Stunning River Views – Take in breathtaking vistas of the Ohio River from porches, balconies, and living spaces—perfect for morning coffee or sunset conversations.
★ Spacious & Sophisticated – Featuring 8 elegantly appointed bedrooms and 6 bathrooms, with open, light-filled living areas designed for comfort, style, and connection.
★ Chef’s Dream Kitchens – Two fully equipped gourmet kitchens offer high-end appliances and thoughtful details, ideal for preparing and sharing memorable meals.
★ Family & Pet Friendly – Designed with everyone in mind, offering welcoming spaces and amenities to ensure a comfortable stay for families and furry companions alike.
★ Private Backyard Oasis – Unwind in your own outdoor sanctuary with a Hyperdome, hot tub, fire pit, gazebo, BBQ grill, and lawn games—perfect for relaxing nights or joyful celebrations.
★ Entertainment for All Ages – Smart Roku TVs in every room, indoor and outdoor games, and a scenic gazebo ensure fun and relaxation throughout your stay.
★ Perfect for Extended Stays & Celebrations – With 4 washer/dryer sets, parking for 8 vehicles, and the comfort of home, this retreat is ideal for family reunions, group escapes, and special occasions.
Book Your Stay Today!
Experience the perfect blend of riverfront luxury, historic character, and modern convenience in Jeffersonville—your unforgettable getaway awaits.
★ TOP 2025 UPCOMING EVENTS
-Waterfront Park Fourth of July Festival: July 4th, 2025
-360 ALLSTARS: May 25th, 2025
-GHOST: World Tour 2025: July 25th, 2025
-Disney Descendants/Zombies: Worlds Collide Tour: Aug 6th, 2025
-2025 Kentucky State Fair: Aug 14-24th, 2025
-Kentucky Bourbon Festival 2025: Sep 5-7th, 2025
-Bourbon & Beyond: Sept 11-14th, 2025
-Louder than Life: Sept 18-21st, 2025
-Jack O’ Lantern Spectacular: Oct 2025
-Halloween Weekends Louisville South KOA Holiday: Oct 2025
★ OTHER 2025 UPCOMING EVENTS (Including TRADE SHOWS)
-The Big Stomp: July 25th to 26th, 2025
-Equipment Expo: Oct 21th to 24th, 2025
-North American International Livestock Exposition: Nov 6th to 20th, 2025
NOTE:
1) Must be 25 or older to book.
2) Please review house rules before booking. Rental Agreement & Security Hold: Guests must e-sign our rental agreement and Must submit a $500 off-platform security hold that will be collected upon signing rental agreement but it will not be placed until 2 days prior to arrival and released 7 days after departure, if no damages are reported. Please note we are API Connected to a hotel-style software called OwnerRez to safely and securely take off-platform security deposits.
3) ** STRICT CANCELLATION for DERBY/ Bourbon & Beyond **
4) Visitors are not permitted unless you make a special request to the host and receive approval.
5) We have exterior surveillance with voice and recording capabilities of the parking area and front door. They are in place for security of guests and the home. We do NOT have interior cameras nor camera in the backyard.
6) The Dome is not recommended for use during hot summer months. We suggest enjoying the other amenities during warmer months for optimal comfort.
7) We cannot accommodate early check-ins or late check-outs for same-day turnarounds.
8) For days without same-day turnarounds, we offer early check-ins and late check-outs at the following rates: $100 for up to 2 hours, $250 for 2 to 4 hours, and a full day's rate for more than 4 hours.
9) Please note that for cancellations of bookings made on platforms other than Airbnb, a Stripe card processing fee of 3% will be deducted from the total refund.
!! PLEASE REVIEW THE HOUSE RULES BEFORE BOOKING. THANK YOU !!
