Find Resorts & Hotels with Spas in Isle of Palms, SC

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Check availability on Isle of Palms Resorts & Hotels with Spas

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Compare Isle of Palms Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

4.0 star property
8.8 out of 10, Excellent, (1035)
"First time visitors and we look forward to returning, we loved the property and all the food choices were really good, thanks Wild Dunes!"
The price is AED 1,208
AED 1,646 total
includes taxes & fees
3 Apr - 4 Apr
Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

The Palms Oceanfront Hotel

3.5 star property
8.2 out of 10, Very Good, (1096)
"The room was comfortable, and I appreciated the outdoor restaurants. The food was good too. I know this is NO big deal, but the Oceanfront hotel of Ilse of palms charged us $6 fee, b/c we booked thru a 3rd party vendor. Distasteful."
The price is AED 841
AED 967 total
includes taxes & fees
3 Apr - 4 Apr
The Palms Oceanfront Hotel

Seaside Inn Oceanfront

2.5 star property
7.6 out of 10, Good, (1051)
"We enjoyed our girls weekend, we loved the porch area facing the beach, it was perfect for watching the sunrise every morning"
The price is AED 768
AED 884 total
includes taxes & fees
3 Apr - 4 Apr
Seaside Inn Oceanfront

OCEANFRONT / BELLA VISTA / POOL / SPA / ELEVATOR / ELEGANT HOME

9.6 out of 10, Exceptional, (133)
"Beautiful setting "
OCEANFRONT / BELLA VISTA / POOL / SPA / ELEVATOR / ELEGANT HOME

Oceanfront 1st Floor Condo!! Community Pool & Fishing Pier! Iin the Heart of IOP!

9.0 out of 10, Wonderful, (81)
"This was a great place for a quick weekend getaway. Very relaxing, and a lot of things within walking distance. "
The price is AED 594
AED 1,260 total
includes taxes & fees
13 Apr - 14 Apr
Oceanfront 1st Floor Condo!! Community Pool & Fishing Pier! Iin the Heart of IOP!

Cozy Oceanfront 1 Bedroom W/Balcony! Avail. April 7-9, 23rd, 27-30! 2nd floor

9.0 out of 10, Wonderful, (226)
"Thank you for opening your condo to my small family this week. It was a great location. Easy to walk to all things needed. Was able to dolphin watch off the patio too!"
The price is AED 584
AED 1,306 total
includes taxes & fees
7 Apr - 8 Apr
Cozy Oceanfront 1 Bedroom W/Balcony! Avail. April 7-9, 23rd, 27-30! 2nd floor

Port of Call on Isle of Palms ~ OCEAN FRONT, Pool, boardwalk, putting green

9.8 out of 10, Exceptional, (60)
"House is perfect for large groups. "
Port of Call on Isle of Palms ~ OCEAN FRONT, Pool, boardwalk, putting green

Oceanfront 1st Floor Condo!! Community Pool & Fishing Pier! In the Heart of IOP!

9.0 out of 10, Wonderful, (24)
"This property was perfect for our stay. My husband has some mobility issues and it was easy in and out, plus the tiled floor helped. It really had everything we needed and easy to get to the beach. We visit every year in Feb and would love to stay again. The only comment I would have was that since the weather was colder, we needed to use the quilt from the second bedroom on the bed also since the one in the master wasn’t quite warm enough in it’s own. I am sure it would have been fine in the...
The price is AED 738
AED 1,495 total
includes taxes & fees
21 Apr - 22 Apr
Oceanfront 1st Floor Condo!! Community Pool & Fishing Pier! In the Heart of IOP!

Hot tub, Private Pool, Pet Friendly, Sunset Views! - 600 Palm

8.0 out of 10, Very Good, (9)
"Love isle of Palms. It’s a great destination for friends and family."
Hot tub, Private Pool, Pet Friendly, Sunset Views! - 600 Palm

Oceanfront, Modern condo! Can't beat the combo of Location & Luxury! POOL & PIER

9.6 out of 10, Exceptional, (48)
"The unit was very nicely updated and we had everything we needed. One suggestion would be another comfy chair in the living room. The couch was the only place to sit. "
The price is AED 556
AED 1,210 total
includes taxes & fees
13 Apr - 14 Apr
Oceanfront, Modern condo! Can't beat the combo of Location & Luxury! POOL & PIER
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking to vacation at a spa hotel in Isle of Palms?
Forget the stress of everyday life and book yourself a hotel with a spa. Travelers love the beaches in Isle of Palms. Enjoy the live music and many popular restaurants during your vacation. Spa hotels are a great way to take a break from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Isle of Palms?
Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn is a top beach spa hotel featuring 5 pools, 8 restaurants, 9 bars, and a golf course. Enjoy a facial, body scrub, or detox wrap at The Spa at Sweetgrass. Another popular spa hotel in Isle of Palms is Wild Dunes Resort – Residences at Sweetgrass.
How many spa hotels will I find in Isle of Palms?
Among Expedia’s 2022 accommodation options in Isle of Palms, there are 2 spa hotels.
What's there to see and do in Isle of Palms?
Enjoy all that Isle of Palms has to offer and visit Isle of Palms Beach, Front Beach, and Wild Dunes Resort Golf Course. If you have some spare time during your trip, you might want to check out Dewees Island Beach and Isle of Palms County Park.
What is a Isle of Palms spa hotel?
Spa hotels in Isle of Palms provide lodging and have a full on-site spa which offers services like couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.