Find Resorts & Hotels with Spas in Isle of Palms, SC

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Pick from 960 Isle of Palms Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn
4.0 star property
8.8 out of 10, Excellent, (1008)
"We have visited this property multiple times a year for the last 13 years. It’s an amazing property and area. However I always have to spend time away from my vacation to address an error in my charges. And I mean every visit. This visit is no excpetion. I typically get it resolved but it takes time away from my visit and family and is stressful and aggravating to say the least."
The price is AED 764
AED 1,047 total
includes taxes & fees
1 Dec - 2 Dec
Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn
The Palms Oceanfront Hotel
3.5 star property
8.2 out of 10, Very Good, (1018)
"The guy that worked at the reception was in a horrible mood. Was not friendly and welcoming at all. It felt like we were a problem for him. The room was very neat, we loved that. "
The price is AED 439
AED 509 total
includes taxes & fees
10 Nov - 11 Nov
The Palms Oceanfront Hotel
Seaside Inn Oceanfront
2.5 star property
7.6 out of 10, Good, (1010)
"Very nice beachfront hotel, appreciate the toiletries, nicest staff, and great breakfast. "
The price is AED 437
AED 507 total
includes taxes & fees
6 Nov - 7 Nov
Seaside Inn Oceanfront
OCEANFRONT / BELLA VISTA / POOL / SPA / ELEVATOR / NEWLY REMODELED
9.6 out of 10, Exceptional, (128)
"Property was very nice and clean. Plenty of towels for all of our guests was great! Beds were super comfortable! View of the beach was spectacular! Sliding doors were a bit hard to open. Water pressure master bathroom sinks very low. Requested multiple times to try to check in early and was suppose to get a call or text when house was ready. That never happened. Overall beach house was great! Wish we would have had more time to actually stay at the house and enjoy the view and...
OCEANFRONT / BELLA VISTA / POOL / SPA / ELEVATOR / NEWLY REMODELED
Port of Call on Isle of Palms ~ OCEAN FRONT, Pool, boardwalk, putting green
9.8 out of 10, Exceptional, (59)
"Overall experience was great. Only issues we had were the main kitchen sink had a bad leak at one point during the week. And 1 of the 2 dishwashers shorts out and did not work. Other than those it was a beautiful house. Would recommend to others. "
Port of Call on Isle of Palms ~ OCEAN FRONT, Pool, boardwalk, putting green
Oceanfront 1st Floor Condo!! Community Pool & Fishing Pier! Iin the Heart of IOP!
9.0 out of 10, Wonderful, (80)
"We had a wonderful time. The property had beach access, pool and a pier. Great customer service. We would definitely stay here again."
The price is AED 386
AED 926 total
includes taxes & fees
6 Nov - 7 Nov
Oceanfront 1st Floor Condo!! Community Pool & Fishing Pier! Iin the Heart of IOP!
"Oceanfront 1BR & 1 Bath Villa. "OPEN Oct. 26 - Nov. 1." Great Rate!
9.0 out of 10, Wonderful, (217)
"Great location. Clean. Cool set up. Only knock is the walls and or floors aren’t insulated well and you can hear everyone walking up and down the stairs . "
"Oceanfront 1BR & 1 Bath Villa. "OPEN Oct. 26 - Nov. 1." Great Rate!
Stunning Designer Home, Fully Renovated, in Gated Community Near Beach.
10.0 out of 10, Exceptional, (51)
"Stayed here for a baseball tournament and the home was perfect for our family of 6! Clean and had everything we needed for a comfortable stay. Thank you! "
Stunning Designer Home, Fully Renovated, in Gated Community Near Beach.
Bea's Nest Historic Home on Isle of Palms, 5 BR with Pool steps to the ocean
9.6 out of 10, Exceptional, (8)
"We enjoyed this home and all the amenities. The large spaces inside were great for family time and the pool and outdoor sitting area with the fireplace and tv allowed us to enjoy lots of fun while watching ball games and relaxing all at the same time. The close walk (3-5 minutes) to the beach was awesome as we did that every day. A beautiful home and a great community to spend time in. So fun. "
Bea's Nest Historic Home on Isle of Palms, 5 BR with Pool steps to the ocean
Ocean Front - 3 Bedrooms, 3 Baths- Great View, Perfect Location!
9.6 out of 10, Exceptional, (187)
"The property is in a great location. The owner was very responsive to issues during our stay"
Ocean Front - 3 Bedrooms, 3 Baths- Great View, Perfect Location!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking to vacation at a spa hotel in Isle of Palms?
Forget the stress of everyday life and book yourself a hotel with a spa. Travelers love the beaches in Isle of Palms. Enjoy the live music and many popular restaurants during your vacation. Spa hotels are a great way to take a break from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Isle of Palms?
Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn is a top beach spa hotel featuring 5 pools, 8 restaurants, 9 bars, and a golf course. Enjoy a facial, body scrub, or detox wrap at The Spa at Sweetgrass. Another popular spa hotel in Isle of Palms is Wild Dunes Resort – Residences at Sweetgrass.
How many spa hotels will I find in Isle of Palms?
Among Expedia’s 1827 accommodation options in Isle of Palms, there are 2 spa hotels.
What's there to see and do in Isle of Palms?
Enjoy all that Isle of Palms has to offer and visit Isle of Palms Beach, Isle of Palms Marina, and Front Beach. If you have some spare time during your trip, you might want to check out Wild Dunes Resort Golf Course and Dewees Island Beach.
What is a Isle of Palms spa hotel?
Spa hotels in Isle of Palms provide lodging and have a full on-site spa which offers services like couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.