East Prairie, MO
Travel Guide
Visit East Prairie
Pear Tree Inn Sikeston
2602 E Malone Avenue, Sikeston, MO
The price is AED 314 per night from Apr 24 to Apr 25
AED 314
AED 361 total
includes taxes & fees
24 Apr - 25 Apr
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,000 reviews)
Quiet area
"Quiet and comfortable enough to get a good days sleep before working a night shift"
Reviewed on 14 April 2025
Best Western Plus Sikeston
120 S Interstate Drive, Sikeston, MO
The price is AED 331 per night from Apr 24 to Apr 25
AED 331
AED 377 total
includes taxes & fees
24 Apr - 25 Apr
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,000 reviews)
Nice place to stay , quiet and clean
"The gentleman at the front desk was super nice , friendly and just fun when we checked in , we had a quick overnight stay in town ! Pool was clean nice and warm , the next morning breakfast was nice clean and stocked and the young lady cleaning and keeping it full was very friendly also , plus we ..."
Reviewed on 30 March 2025
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner, Sikeston, MO
The price is AED 364 per night from May 18 to May 19
AED 364
AED 418 total
includes taxes & fees
18 May - 19 May
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,000 reviews)
"Wonder stay! Excellent hotel."
Reviewed on 13 April 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Dancing Diamonds Waterfront Retreat
Tiptonville
Stay at this vacation home in Tiptonville. Enjoy free WiFi, patios, and an in-room coffeemaker. Popular attractions Reelfoot Lake State Park and Campbell's Point ...
10/10 Exceptional! (84 reviews)
Great property
"Very quiet. Comfortable beds, Great location."
Reviewed on 15 February 2025
Lake House scales and duck
Hornbeak
Stay at this vacation home in Hornbeak. Enjoy free WiFi, a garden, and patios. Popular attractions Willow Towhead and Reelfoot Lake are located nearby.
9.8/10 Exceptional! (65 reviews)
True Hospitality
"The real gem here is the owners and maintenance team. In touch throughout the stay to make sure we had what we needed. Communication even after we left on a ‘valuable’ we left behind. Picked a terrible weather week but they checked on us multiple times to be sure we were safe. Clean, comfortable ..."
Reviewed on 8 April 2025
Duck Hunting, Fishing or Relaxing Family Vacation
Hornbeak
Stay at this vacation home in Hornbeak. Enjoy a garden, patios, and in-room washers/dryers. Popular attractions Willow Towhead and Reelfoot Lake are located ...
9.8/10 Exceptional! (188 reviews)
Good Stay
"The place was nice. Instructions were clear. Owner was in touch with us. We had very bad weather while we were there. Went for fishing, only got a bit in due to weather."
Reviewed on 9 April 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Big Oak Tree State Park
4.5/5(3 reviews)
You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.
- Big Oak Tree State Park
- Mississippi River
- Ohio River
- Reelfoot Lake
- Reelfoot Lake State Park
- Discovery Park of America
- Columbus-Belmont State Park
- Union City Masquerade Theatre
- Marston Community Center
- Campbell's Point
- The Book Bug
- Central Park
- Graham Park
- Sikeston Depot Museum
- New Madrid Historical Museum
- Fort Defiance State Park
- River Ridge Winery
- Boot Heel Golf Club
- Hunter-Dawson State Historic Site
- Front Street Studio & Art Gallery