Downtown Syracuse Vacations

Book a Hotel + Flight together to unlock savings

  • Plan, book, travel with confidence

    • payments icon
    Better together
    Save up to AED 148 when you book a flight and hotel together*
    lob hotels icon
    Find the right fit
    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon
    Rest easy
    Plan, book, and manage your trip all in one place

Where to stay in Downtown Syracuse

Find the best Downtown Syracuse areas and neighborhoods for the activities you enjoy most. Learn more about Downtown Syracuse
Default Image

Lakefront

1 out of top 10 points of interest in this area
4/5(60 area reviews)

Bordering Downtown Syracuse, Lakefront features the charming areas of Franklin Square and Inner Harbor. Explore the historic O.M. Edwards Building, listed on the National Register of Historic Places.

Find hotels in Lakefront

Downtown Syracuse Hotel Deals

Marriott Syracuse Downtown
Marriott Syracuse Downtown
4 out of 5
100 East Onondaga Street, Syracuse, NY
Fully refundableReserve now, pay when you stay
The price is AED 467 per night from Mar 23 to Mar 24
AED 467
AED 537 total
includes taxes & fees
23 Mar - 24 Mar
8.4/10 Very Good! (1,002 reviews)
"Great room. Great service. I would not recommend the room service. DoorDash instead. It’s probably faster."

Reviewed on 19 March 2025

Marriott Syracuse Downtown
Best Western Syracuse Downtown Hotel and Suites
Best Western Syracuse Downtown Hotel and Suites
3 out of 5
416 S Clinton St, Syracuse, NY
Fully refundableReserve now, pay when you stay
The price is AED 482 per night from Mar 26 to Mar 27
AED 482
AED 554 total
includes taxes & fees
26 Mar - 27 Mar
8.2/10 Very Good! (432 reviews)
"We turn on the a/c because it was very warm in the room, it ran all night but it never got under 74 degrees. It was difficult to sleep. On a good note, the water pressure was amazing, the towels were soft, and the shampoo/conditioner/body wash was terrific as well."

Reviewed on 20 March 2025

Best Western Syracuse Downtown Hotel and Suites
Courtyard Syracuse Downtown At Armory Square
Courtyard Syracuse Downtown At Armory Square
3 out of 5
300 West Fayette Street, Syracuse, NY
Fully refundableReserve now, pay when you stay
The price is AED 492 per night from Apr 6 to Apr 7
AED 492
AED 566 total
includes taxes & fees
6 Apr - 7 Apr
8.6/10 Excellent! (588 reviews)
"Nice place and very nice staff"

Reviewed on 20 March 2025

Courtyard Syracuse Downtown At Armory Square
See all 526 properties in Downtown Syracuse
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Downtown Syracuse

Landmark Theatre showing interior views and heritage elements

Landmark Theatre

4/5(71 reviews)

Get tickets for a show at Landmark Theatre, a storied theater in Syracuse. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Landmark Theatre
Armory Square featuring a city

Armory Square

4.5/5(177 reviews)

You can find out about the history of Syracuse when you stop by Armory Square. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Armory Square
Museum of Science and Technology featuring interior views

Museum of Science and Technology

4/5(64 reviews)

You can spend time browsing the exhibits at Museum of Science and Technology during your travels in Syracuse. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Museum of Science and Technology