The Best Business Hotels in Downtown Des Moines, IA from AED 334 in 2025

Check availability on Downtown Des Moines Business Hotels

Tonight

Tomorrow

This weekend

Next weekend

Compare Downtown Des Moines Business Hotels room rates, reviews, and availability. Most hotels are fully refundable.

"The staff and hotel are top notch"

AED 695 total

includes taxes & fees

31 Jan - 1 Feb

"Comfortable beds, clean, and convenient place to stay near hospitals in Des Moines"

AED 416 total

includes taxes & fees

7 Feb - 8 Feb

"Food options "

AED 486 total

includes taxes & fees

16 Feb - 17 Feb

"Lovely hotel and awesome breakfast!"

AED 504 total

includes taxes & fees

27 Feb - 28 Feb

"When I made the reservation I put in a request to see if we could get a higher floor because my son is really interested in skyscrapers. The lady at the front desk was very friendly and helpful. She talked to my son about the tallest buildings nearby and she put us on the highest floor she could find available. My son was really happy. It made the stay extra special. Thank you!"

AED 592 total

includes taxes & fees

16 Feb - 17 Feb

"I love how close it is to everything, room was extremely quiet! "

AED 374 total

includes taxes & fees

7 Feb - 8 Feb

"Loved the view of the river, how close it was to downtown and lots of day time options for exploring "

AED 451 total

includes taxes & fees

16 Feb - 17 Feb

"Beautiful room for a night in together. "

AED 514 total

includes taxes & fees

7 Feb - 8 Feb

Find out more about Downtown Des Moines

Recent reviews of Downtown Des Moines hotels

Embassy Suites Hotel Des Moines Downtown

5/5 Excellent

"Food options "

A verified traveler stayed at Embassy Suites Hotel Des Moines Downtown

Posted 3 days ago

Hampton Inn & Suites Des Moines Downtown

5/5 Excellent

"We enjoyed our stay at this Hampton Inn, primarily for its cleanliness and convenient walkable location. It was easy to get to downtown for New Year's Eve festivities. Some reviews said the parking garage charge is $15 -- this has now been updated to $20. But there is street parking that is only charged during business hours and free on holidays, so we made good use of that option. The breakfast had a few hot items, so it was better than just continental fare, but we were not that impressed. The eggs and sausage didn't seem like real food, unfortunately. Otherwise, it was a good spot and a lovely stay."

Find Business Hotels in Downtown Des Moines, IA

Plan, book, stay with confidence

Check availability on Downtown Des Moines Business Hotels

Compare Downtown Des Moines Business Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Des Lux Hotel

Comfort Inn & Suites Event Center

Embassy Suites Hotel Des Moines Downtown

Staybridge Suites Des Moines Downtown, an IHG Hotel

Des Moines Marriott Downtown

Hyatt Place Des Moines/Downtown

Hampton Inn & Suites Des Moines Downtown

Renaissance Des Moines Savery Hotel

Residence Inn Des Moines Downtown

Holiday Inn Downtown - Mercy Area, an IHG Hotel

Find out more about Downtown Des Moines

Recent reviews of Downtown Des Moines hotels

Embassy Suites Hotel Des Moines Downtown

Comfort Inn & Suites Event Center

Staybridge Suites Des Moines Downtown, an IHG Hotel

Des Lux Hotel

Holiday Inn Express & Suites Des Moines Downtown, an IHG Hotel

AC Hotel Des Moines East Village

Hyatt Place Des Moines/Downtown

Holiday Inn Downtown - Mercy Area, an IHG Hotel

Hampton Inn & Suites Des Moines Downtown

Explore a world of travel with Expedia

Find More Hotels near Downtown Des Moines

More Hotel Options in Downtown Des Moines

More Accommodation Types in Downtown Des Moines

Hotels near popular Des Moines Attractions

Downtown Des Moines Hotels by Star Rating

Explore more hotels