Cape Girardeau Vacations

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Find the Best Cape Girardeau Vacation Packages

Cape Girardeau Hotel Deals

The Riverview
The Riverview
3.5 out of 5
777 Main St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is AED 354 per night from Mar 18 to Mar 19
AED 354
AED 399 total
includes taxes & fees
18 Mar - 19 Mar
9.2/10 Wonderful! (165 reviews)
"Very clean,big comfortable bed, coffee maker was nespresso and nasty need a regular coffee maker and nice bathroom but shower only had a half door so water went everywhere in the floor. But overall very nice hotel."

Reviewed on 27 February 2025

The Riverview
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
3 out of 5
3351 Percy Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is AED 364 per night from Mar 9 to Mar 10
AED 364
AED 410 total
includes taxes & fees
9 Mar - 10 Mar
9.4/10 Exceptional! (1,004 reviews)
"The staff from check-in to check-out was very friendly! The greeted everyone at the social and at breakfast! Thank you for the wonderful stay!"

Reviewed on 2 March 2025

Drury Plaza Hotel Cape Girardeau Conference Center
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
2.5 out of 5
3253 William Street, Cape Girardeau, MO
Fully refundable
The price is AED 364 per night from Mar 16 to Mar 17
AED 364
AED 410 total
includes taxes & fees
16 Mar - 17 Mar
9.4/10 Exceptional! (1,004 reviews)
"We enjoyed our stay and would recommend"

Reviewed on 3 March 2025

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
See all 153 properties in Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Cape Girardeau vacation package cost?
Offering excellent value package deals on Expedia, you’ll be pleasantly surprised at how much a vacation to Cape Girardeau costs! Expedia’s packages make travel planning easier and save you more.
What are the cheapest months to go to Cape Girardeau?
December, January and February are great times to look for cheap Cape Girardeau vacation packages. Traveling in less busy months means you’ll typically find better prices on hotels and flights.
How to find the best Cape Girardeau package deals?
Start your search for a Cape Girardeau package deal by entering your preferred travel dates and destination under our “Packages” tab. Then select some filters, like “Popular locations” and “Property type,” to fine-tune the results to your exact style. You can also sort by “Package discount” and discover offers that come with unbeatable savings. If you don’t find the perfect Cape Girardeau package deal right away, simply change your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Cape Girardeau adventure underway.
Is it cheaper to book a Cape Girardeau vacation as a package?
You can enjoy significant savings on your Cape Girardeau retreat by booking a tailored vacation package. Click on the “Package” heading, then enter your destination and travel dates to view the best flight and hotel prices. Bundling can save travelers hundreds of dollars. Consider adding a car rental and you may land a better deal.
When to book a vacation package to Cape Girardeau?
If you’re planning a spontaneous Cape Girardeau trip, browse our last-minute deals that can be booked up to one week before you go. Prefer not to wait until the last minute? You can land awesome deals on your flights and hotels by booking well in advance.
How to plan a trip to Cape Girardeau?

  1. Pick the best time to travel: Your schedule, preferred season and the type of weather you like can all impact your decision on when to visit Cape Girardeau.
  2. Plan your budget wisely: On top of the price of your stay, you should consider other expenses. These include food, transportation and flights. Also, set aside some extra funds for unexpected costs that may come up during your trip to Cape Girardeau.
  3. Decide how many days away: Start by listing all the attractions and activities you want to get to in Cape Girardeau. Then, estimate how long you’ll need for each, as well as any travel time.
  4. Combine your accommodations and airfare: Once you’ve nailed down your travel dates and duration, book the perfect Cape Girardeau vacation package for you.

Discover the most popular places to visit in Cape Girardeau

Southeast Missouri State University

4.5/5(76 reviews)

Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.

Southeast Missouri State University

Isle Casino Cape Girardeau

4.5/5(48 reviews)

Why not roll the dice with a visit to Isle Casino Cape Girardeau during your travels in Cape Girardeau? While in this family-friendly area, you can savor the top-notch restaurants.

Isle Casino Cape Girardeau

Saint Francis Medical Center

Though Saint Francis Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of Cape Girardeau while you are here.

Saint Francis Medical Center